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MLE > USMLE Micro virology > Flashcards

USMLE Micro virology Flashcards

1
Q

Questions

A

Answers

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2
Q

only ssDNA virus

A

parvovirus (par one)

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3
Q

only dsRNA virus

A

reovirus (REpeatOvirus)

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4
Q

Naked RNA viruses

A

NAKED CPR

Calicivirus, Picornavirus, Reovirus

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5
Q

Which virus acquires its envelop from nuclear membrane

A

Herpesvirus

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6
Q

which virus is diploid

A

retrovirus has 2 identical copies of ssRNA

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7
Q
  1. Where do DNA viruses replication

2. Exception

A
  1. nucleus

2. poxvirus (carries its own DNA-dependent RNA pol)

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8
Q
  1. Where do RNA viruses replication

2. exception

A
  1. cytoplasm

2. influenza, retrovirus

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9
Q

DNA viruses

A

HHAPPPy
Hepadna, Herpes
Adeno
Pox, Pavo, Papova

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10
Q

All DNA viruses are linear except…

A

Papovavirus (circular, supercoiled)

Hepadena (circular, incomplete)

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11
Q

All DNA viruses are ichosahedra except…

A

POX IN A BOX

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12
Q

Naked DNA viruses

A

You need to be naked for a PAP

Papova
Adeno
Parvo

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13
Q

Enveloped DNA

A

HPH

Hepadna
Pox
Herpes

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14
Q
  1. What type of immunity do live attenuated vaccines confer?

2. Why can’t they be given to immunocompromised patients

A

Humoral and cell-mediated

may revert to virulence

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15
Q

Immunity conferred by killed vaccines

A

humoral

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16
Q

Which vaccines are live attenuated?

A 
MMR
Sabin 
VZV
yellow fever
smallpox
adeno
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17
Q

Which vaccines are killed?

A

RIP Always: Rabies, Infulenza, salk Polio, HAV

SalK = Killed

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18
Q

Egg-based

A

FRY an egg: Flu, MMR, Yellow fever

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19
Q

Recombinant vaccine

A

HBV

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20
Q

Negative stranded viruses

A 
Always Bring Polymerase or Fail Replication
Arenavirus
Bunyavirus
Paramyxovirus
Orthomysovirus
Filovirus
Rhabdovirus
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21
Q

Segmented Viruses

A

BOAR

Bunya
Orthomyo
arena
reo

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22
Q

Picornavirus

A

PERCH on a “peak”

Polio
Echo
Rhino
Coxsachie
HAV
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23
Q

MCC infantile gastroenteritis

A

Rota

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24
Q

MCC common cold

A

rhino

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25
Q

Name the 4 paramyxoviruses

A 
PaRaMyxovirus:
Parainfluenza - croup
RSV - bronchiolitis in babies
Measles
Mumps
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26
Q

Mumps: Virus, symptoms

A
  1. paramyovirus w/ 1 serotype

2. Parotitis, orchitis, aspetic Meningitis

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27
Q

Koplik spots

A

measles

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28
Q

Measles symptoms

A

3C’s: cough, coryza, conjunctivitis

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29
Q

Measles describe rash

A

head to toe spread

30
Q

Measles complications

A

subacute sclerosing panencephalitis SSPE
encephalitis
giant cell pneumonia

31
Q

Influenza prophylaxis and tx

A

Influenza A prophylaxis: Amantadine and rimantadine

A and B: Zanamivir and osteltamivir

32
Q

negri bodies

A

rabies

33
Q

bullet-shaped capsid

A

rabies

34
Q

HSV-1: diseases

A

Gingivostomatitis
Keratoconjunctivitis
oral (and some gential) lesions
temporal lobe encephalitis

35
Q

heterophilic + mono

A

EBV

36
Q

roseola (exanthem subitum)

A

HHV-6

37
Q

adenovirus: diseases

A 
pharyngitis & pneumonia
ARD
PCF
Keratoconjunctivitis
GU infections
enteric infections
38
Q

fifth disease

A

B19 parvovirus

39
Q

parvovirus: diseases

A

fifth disease - erythema infectiosum
hydrops fetalis
aplastic crises in sickle cell disease

40
Q

HHV8

A

kaposi sarcoma

41
Q

papova: diseases

A

HPV
JC - progressive multifocal leukoencephalopathy
BK

42
Q

Pox: diseases

A

small pox
vaccinia - cowpox
molluscum contagiosum

43
Q

coxsackie: diseases

A

aspeptic meningitis
herpangina
hand/foot/mouth disease
myocarditis

44
Q

calicivirus: diseases

A

HEV

norwalk - gastroenteritis

45
Q

Reo: diseases

A

Reo - colorado tick fever

rota

46
Q

1 cause of fatal diarrhea in children

A

rotavirus (reovirus)

47
Q

Flavi: diseases

A 
HCV
Yellow fever
dengue
st. louis encephalitis
west nile
48
Q

Togavirus: diseases

A

Rubella (germal measles)
WEE
EEE

49
Q

Retro: diseases

A

HIV - AIDS

HTLV - T cell leukemia

50
Q

Cornonavirus: diseases

A

corona

SARS

51
Q

Paramyxovirus: diseases

A

Parainfluenza - croup
RSV - bronchioliltis in babies
Measles
Mumps

52
Q

Filo: diseases

A

Ebola/marburg hemorrhagic fever

53
Q

arena: diseases

A

LCV - lymphocytic choriomeningitis

Meningitis - spread by mice

54
Q

Bunyavirus: diseases

A

California encephalitis
sandfly/rift valley fever
crimean-congo hemorrhagic fever
hantavirus - hemorrhagic fever, pneumonia

55
Q

mechanism of antigenic shift and drift

A

shift - genetic reassortment
drift - mutations

Sudden Shift is more deadly than a graDual Drift

56
Q

Arbovirusus

A

Borne virus: flavi, toga, bunyavirus

transmitted by arthropods

57
Q

high fever, black vomitus, jaundice, councilman bodies (acidophilic inclusions)

A

Yellow fever (flavi)

58
Q

Atypical lymphocytes

A

mono caused by EBV

59
Q

Diagnosis of HSV

A

Tzanck test - look for multinucleated giant cells

Tzanck heavens I do not have herpes

60
Q

Hepatitis serologic markers: best test to detect active HAV

A

IgM HAV Ab

61
Q

Hepatitis serologic markers: continued presence indicates carrier state

A

HBsAg

62
Q

Hepatitis serologic markers: immunity to HBV

A

HBsAb

63
Q

Hepatitis serologic markers: core of HBV

A

HBcAg

64
Q

Hepatitis serologic markers: Ab + during window phase

A

HBc Ab

IgM is an indicator of recent disease

65
Q

Hepatitis serologic markers: indicator of transmissibility

A

HBeAg

66
Q

Hepatitis serologic markers: low transmissibility

A

HBeAb

67
Q

Hepatitis serologic markers: + during Acute Disease

A 
HBsAg
HBcAB (IgM = acute, IgG = chronic)
68
Q

Hepatitis serologic markers: + during complete recovery

A

HBsAb

HBcAb

69
Q

Where are gp41 and gp120 found

A

envelop proteins of HIV

70
Q

DOC for Onchocerciasis

A

rIVER blindness is treated with IVERmectin

MLE (11 decks)

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