Urology: Urinary Stones/Renal Colic Flashcards

1
Q

what is urolithiasis?

A

the formation of stony things within the urinary tract

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2
Q

metabolic cause of urolithiasis

A
  • hyperparathyroidism
  • idiopathic hypercalcuria
  • disseminated malignancy
  • hypervitaminosis D
  • sarcoidosis
  • hyperthyroidism
  • cystinuria
  • hyperoxaluria
  • xanthinuria
  • hyperuricuria
  • renal tubular acidosis
  • primary kidney disease
  • drugs
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3
Q

what type of calculous disease is common in developed countries?

A

upper urinary tract calculi

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4
Q

aetiology of calculous disease

A
  • secondary to dehydration
  • infection
  • anatomical malformations
  • metabolic disorders
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5
Q

types of calculi

A
  • calcium oxalate
  • phosphate
  • urate
  • cystine
  • xanthine and pruvate
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6
Q

why are calcium oxalate stones important?

A
  • they are the most common type of stone
  • they have sharp projections
  • cause bleeding and they themselves are black due to altered blood on their surface
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7
Q

which type of stone causes staghorn stones?

A

phosphate/struvite stones

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8
Q

signs and symptoms of renal stones

A
  • continuous loin pain
  • colic (if the stone becomes lodged at the PUJ)
  • microscopic haematuria
  • might have associated infection
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9
Q

signs and symptoms of ureteric stones

A
  • colicky pain radiating from loin to groin
  • sweatiness
  • restlessness
  • naseous
  • vomiting
  • microscopic haematuria
  • might have associated infection
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10
Q

investigations for calculous disease

A
  • urine dipstick: microscopic haematuria and possible infection
  • MSSU for C&S
  • U&E
  • FBC
  • CRP
  • CTKUB w/o contrast
  • KUB radiograph
  • USS (hydronephrosis)
  • IVU
  • serum Ca, phosphate, uric acid
  • 24h urine for Ca, phosphate, oxalate, urate, cystine and xanthine
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11
Q

treatment of an acute episode of renal calculi

A
  • analgesia (may require opiates)
  • antiemetic
  • increased fluids
  • collect and sieve out calculi for analysis
  • IV antibiotics, if infection
  • decompression if obstruction is present - done by percutaneous nephrostomy or ureteral stent
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12
Q

how can you remove a stone?

A
  • it can be passed through urine if the stone is <4mm, maybe if <6mm
  • > 6mm have to be removed
  • medical explusive therapy: nifedipine or beta-blockers
  • ureteroscopy and fragmentation done by lase, ultraspound or electro-hydraulic intracorporeal lithotripsy
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13
Q

how to prevent recurrent renal/bladder calculi?

A
  • good fluid intake: 2-3L/day
  • reduced Ca intake
  • treat UTI promptly
  • using Na2CO3 to alkalinise the urine in case of cystine and urate stone
  • if there is uric stone: allopurinol
  • oxalate stone: reduce oxalate intake
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14
Q

where are bladder calculi common?

A

developing countries

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15
Q

symptoms of bladder calculi

A
  • dull suprapubic discomfort
  • dysuria
  • difficulty initiating urination
  • strangury
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16
Q

treatment of bladder calculi

A
  • always intervene
  • <5cm: removed cystoscopically after crushing/fragmenting them
  • > 5cm: suprapubic cystoscopy
17
Q

where are the calculi more likely to lodge?

A
  • pelviureteric junction
  • pelvic brim
  • vesicoureteric junction
18
Q

what is calculous disease associated to?

A
  • ESKD
  • bone diseases
  • hypertension
  • myocardial infarction
19
Q

causes of hypercalcaemia

A
  • primary hyperparathyroidism
  • vitamin D ingestion
  • sarcoidosis
20
Q

causes of hypercalcuria

A
  • hypercalcaemia
  • excessive dietary intake of Ca
  • excessive resorption of Ca from the skeleton, such as occurs with prolonged immobilisation or weightlessness
  • idiopathic hypercalcuria
21
Q

causes of hyperoxaluria

A
  • genetic (alanine-glyoxylate aminotransferase deficiency and gloxylate reductase hydroxypyruvate reductase deficiency) - in these cases, CKD develops early on and a liver transplant is needed to cure the metabolic defect
  • excess ingestion high in oxalate
  • dietary calcium restriction
  • GI disease and increased absorption of oxalate in the colon
22
Q

causes of hyperuricaemia

A
  • idiopathic gout
  • myeloproliferative disorders
  • dehydration can cause these to form stones
23
Q

drugs associated with stone formation

A
  • loop diuretics
  • antacids
  • glucocorticoids
  • theophylline
  • vitamin C and D
  • acetazolamide
  • thiazide
  • salicylates
24
Q

differential diagnosis to renal stones

A
  • acute appendicitis
  • diverticulitis
  • salpingitis
25
Q

complications of renal stones

A
  • obstructing urinary flow
  • infection
  • local tissue damage
  • decreased renal function
  • renal failure
26
Q

what should you look for in a general inspection for renal calculi?

A
  • corneal or conjunctival calcification
  • gouty tophi
  • arthritis
  • features of sarcoidosis
27
Q

indications for urgent stone removal

A
  • obstruction
  • infection
  • persistent and recurrent pain
  • urosepsis
28
Q

differential diagnosi of calcification on plain AXR

A
  • renal stones
  • calcified mesenteric glands
  • gallstones
  • faecolith
  • aortic aneurysm