Cardio: Aneurysms Flashcards
what is an aneurysm?
an abnormal dilatation of an artery
classification of aneurysms
- true aneurysm
- false aneurysm
what is a true aneurysm?
this contains all layers of the vessel wall; appears as either a fusiform or a saccular dilatation
what is a false aneurysm?
these do not contain all layers of the arterial wall; usually involves only a collection of blood in the adventitia
causes of true aneurysm
- congenital: berry aneurysm of circle of Willis, aneursymal varices associated with AV fistula, connective tissue disorders (Marfan’s, Ehlers-Danlos), inflammatory (Takayasu’s aortitis)
- acquired: trauma (irradiation) infection (syphilis, mycotic aneurysm), degeneration (arteriosclerosis, cystic medical necrosis), atheroma
- the bigger the aneurysm, the quicker it will expand
causes of false aneurysm
trauma
common sites of aneurysm
- aorta (more commonly, infrarenal)
- iliac artery
- femoral artery
- popliteal artery
complications of an aneurysm
- rupture
- thrombosis
- distal emboli
- fistula
- pressure on other structures
types of aortic aneurysms
- thoracic
- thoracoabdominal
- abdominal
where can the aorta dilate
from the ascending aorta to the aortic bifurcation
why do aneurysms occur?
degeneration of the elastic lamellae and smooth muscle loss
from when is aorta considered to have an aneurysm?
greater than 3cm across
risk factors for aneurysms
- elastic degeneration due to increased levels of metalloproteinases
- flow dynamics
- hypertension (involved in formation and rate of expansion)
- atherosclerosis
- collagen defects
- genetic association
- smoking (associated with a more rapid expansion)
- associated with emphysema and inguinal hernias
symptoms of aneurysms
- mainly asymptomatic
- backache (pressure on the vertebral bodies)
- sign: pulsatile abdominal mass just above the umbilicus
investigation of aneurysms
- ultrasound (assess the diameter)
- CT scan
- pre-op investigations: FBC, U&E, clotting studies, ECG, CXR, lung function tests, ABGs, echo
where can aneurysm bleed into?
retroperitoneal or intraperitoneal or into the IVC (AV fistula)
management of aortic aneurysm
- depends on the size
- <5cm: monitored annually if <4.5cm or biannually if >4.5cm
- > 5cm: investigated to check whether he is fit for surgery
- only aneurysms >5.5cm (>5cm in women) are considered for surgery or if the patient is symptomatic
treatment options of aortic aneurysm
- EVAR (endovascular repair - stenting)
- open surgery
risk factors for aortic dissection
- hypertension
- smoking
- female
- strong family history
- COPD
- shape of aneurysm (saccular>cylindral)