UROLOGY Chap 537-547 Flashcards
Embryonic devt:
Collecting system completely formed
7th week
*30% of nephrons formed
Embryonic devt:
Nephrogenesis complete by..
36th week
Fetal GFR
25 ml/min/1.73m²
*triples 3mos post term
Rate of urine production of fetal kidneys
50ml/hr
Syndrome associated with bilateral renal agenesis
Incompatible with life
POTTER syndrome
P - pulmonary hypoplasia (cause of death) O - oligohydramnios T - twisted face (potter facie) T - twisted skin (wrinkly skin) E - extermity defect R - renal agenesis (bilateral)
Absent kidney development secondary to defect of the Wolffian duct, ureteric bud, or metanephric blastema
Increased in newborns with SINGLE umbilical ARTERY
Renal agenesis
Maldevelopment of the kidneys
Renal dysgenesis
*types: dysplasi, hypoplasia, cystic
Congenital
Kidney is replaced by cysts, and does not fynction
Usually unilateral
MCC of an abdominal mass in the newborn
Multicystic Dysplastic Kidney (MCDK)
*bilateral - incompatible with life
Small, nondysplastic kidney with fewer than normal number of calyces and nephrons
Renal hypoplasia
- unilateral - incudental finding
- bilateral - leading cause of ESRD in 1st decade of life (polyuria and polydipsia)
Small kidneys (weight not more than 35g)
1 or more deep grooves on the lateral convexity
Parenchyma consists of tubules resembling those in THYROID GLANDS
Severe hypertension by 10yrs old
Ask - Upmark kidney (segmental hypoplasia)
*Nephrectomy controls hypertension
Lower poles of the kidneys fuse
*associated with TURNER SYNDROME
Horseshoe kidney
*high risk for developing Wilms tumor
Abdomina/flank pain, fever, malaise, nausea, vomiting
Pyelonephritis
Renal mass caused by acute focal infecyion without liquefaction
Acute lobar nephronia
UTI with bladder involvement
Sx: dysuria, urgency, frequency, suprapubic pain, incontinence, malodorous urine
Cystitis
Cystitis more common in boys
Self limiting
(+) hematuria lasting for 4 days
Adenovirus cystitis