urogyn Flashcards
prevalence of bladder pain syndrome
2.3-6.5%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
ratio of BPS in women vs men
2-5x more common in women
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: voiding relieves in pain in ___%
57-73%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: stress aggravates pain in ___%
61%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: sex aggravates pain in ___%
50%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: constrictive clothing aggravates pain in ___%
49%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: foods that aggravate pain and percentages
Acidic beverages 54%
Coffee 51%
Spicy foods 46%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: overall, pain worsened with certain food or drink, bladder filling and improved with voiding in ___% of patients
97%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: 12% of women have history of ____
chlamydia
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: detrusor overactivity present in ____% of BPS patients
14%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS management: dietary modification improved ___%
87.6%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS management: relaxation improved
7 6.4%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: 2nd line management
AFTER FAILED PRIMARY CARE
PO amitryptiline 10-100mg over 4 months
PO cimetidine 400mg over 3 months
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: 3rd line management
6 main points
AFTER MDT
1) Lidocaine - 5 day course 200mg, 30% improvement
2) Hyaluronic acid 4-10 weeks
3) Botox
4) DMSO two sessions per week x 2 weeks
5) 10 000 units heparin x 3 months
6) 2% chondroitin sulfate
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: % of women requiring ISC after botox treatment
7%
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: 4th line management
5 main points
- cystoscopic fluguration
- neuromodulaiton
- oral cyclosporin A
- cystoscopy +/- hydrodistention
- major surgery
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
BPS: do not do
- PO Hydroxyzine
- PO pentosan polysulfate
- Longterm abx
- Intravesical resinferation
- Intravesical BCG
- High pressure/long duration hydrodistention
- long-term PO steroids
RCOG GTG 70. Management of bladder pain syndrome. BJOG 2016; 124: e46–e72.
incidence of vault prolapse
0.2-43%
incidence of vault prolapse requiring surgical repair
6-8%
Prolapse stage: most distal point >cm above hymen
stage 1
prolapse stage: most distal point between 1cm above and 1 cm below hymen
stage 2
prolapse stage: most distal point >1cm below hymen by <2cm of TVL
stage 3
prolapse stage: leading edge equal or greater than TVL; or <2cm still above hymen
stage 4
prevention of vault prolapse during VH
McCall culdoplasty or SSF
prevention of vault prolapse during TAH or VH
suturing of cardinal and uterosacral ligaments to cuff
prevention of vault prolapse at VH if vault descends to introitus
SSF
primary POP repair: at 6y, what % will have leakage
41%
primary POP repair: at 6y, what % will have bulge
18%
primary POP repair, at 6y what % will have fecal incontinence
15%
PHVP - first line management for stage I-II
pelvic floor muscle training
PVHP - first line management for stage III-IV
vaginal pessaries
PVHP - when to offer surgical treatment
if symptomatic
PVHP - first line surgical option
abdominal sacrocolpoplexy (78-100%)
PVHP - recurrent vault prolapse
MDT
PVHP - risk of sexual dysfunction and short vaginal length
SSF
urinary incontinence overall prevalence
25% of women
after menopause, 50%
urinary incontinence: breakdown of types
49% stress
29% mixed
22% OAB
pelvic floor training for UI
3 months, 8 contractions 3x per day
pelvic floor training for prolapse
16 weeks
OAB: follow-up schedule if starting anitcholinergics
4 weeks
then 12/12 at GP if established
or 6/12 if >75yo
anticholinergics contraindicated in:
myasthenia gravis UC toxic megacolin GI or bladder obstruction Dementia
SUI: surgical options
ALL MUST BE AGREED AT MDT
1) colposuspension = gold standard
2) autologous rectus fascial sling
3) intramural bulking agents
SUI: medication option
duloxetine (SNRI):
increases urethral sphincter tone
56% reduction in incontinence
17-22% discontinuation rate (usually due to nausea, but resolves 1 month in 88%)
OAB: botox options
1) 100 units
2) review in 12 weeks
3) increase to 200 units if inadequate
anticholinergics for OAB:
oxybutinin
tolteridone
darifenacin
trospium
do not use these anticholinergics for OAB
flavoxate
propantheline
imipramine
colposuspension: urge or urge UI
up to 17%
colposuspension: exacerbation of recto-enterocele
14%
colposuspension: dyspareunia
1/20-25
symptomatic women with + leukocytes and + nitrites
prescribe abx
symptomatic women with - leukocytes/nitrites
consider abx
asymptomatic women with + leukocytes and nitrites
do not give abx, await C+S
OAB first line
bladder retraining 6 weeks