sepsis and antibiotics

Question 1

mastitis: MSSA strep - allergy

Answer 1

vanc + clindamycin

Question 2

sepsis mixed ScvO2 target

Answer 2

> 65%

Question 3

vanc/teic/linezolid/daptomycin DO cover

Answer 3

anaerobes, MRSA, gram positives (staph, GAS, GBS)

Question 4

mastitis: MSSA streptococci

Answer 4

fluclox + clindamycin

Question 5

sepsis indications for ICU: neuro

Answer 5

reduced consciousness

Question 6

co-amox does not cover

Answer 6

MRSA, pseudomonas

Question 7

TSSS - MRSA

Answer 7

vanc + clindamycin + gentamicin stat

Question 8

gram positives

Answer 8

MRSA, staph aureus, GAS, GBS

Question 9

anaerobes

Answer 9

clostridia, bacteroides, peptostreptococci

Question 10

sepsis indications for ICU: renal

Answer 10

dialysis

Question 11

Carbapenems do not cover

Answer 11

MRSA

Question 12

c/s wound infection: MSSA strep - allergy

Answer 12

vancy + clindamycin

Question 13

endometritis

Answer 13

gentamicin stat + cefotaxime + metronidazole

Question 14

STSS (strep) criteria

Answer 14

A - isolation of GAS from sterile or non-sterile site

B - clinical case definition: multi-organ involvement, including hypotension

Question 15

breast abscess in untreated mastitis

Answer 15

3%

Question 16

c/s wound infection: MRSA strep

Answer 16

vanc + clindamycin

Question 17

first sign of sepsis

Answer 17

tachypnea

Question 18

mastitis: MRSA strep - allergy

Answer 18

clindamycin/teicoplanin

Question 19

sepsis indications for ICU: cardiovascular

Answer 19

decreased BP or increased lactate despite fluids

Question 20

sepsis glucose target

Answer 20

<8.3

Question 21

incidence of rash in STSS

Answer 21

10%

Question 22

endometritis - allergy

Answer 22

gentamicin + clindamycin + ciprofloxacin

Question 23

pyelonephritis

Answer 23

cefotaxime + gentamicin stat

Question 24

pyelonephritis - allergy

Answer 24

gentamicin + ciprofloxacin

Question 25

severe sepsis - no focus - allergy

Answer 25

clindamycin + gentmicin + metronidazole + ciprofloxacirn

Question 26

c/s wound infection: MRSA strep - allergy

Answer 26

clindamycin/teicoplanin

Question 27

vanc/teic/linezolid/daptomycin do not cover

Answer 27

gram negatives (coliform, pseudomonas)

Question 28

sepsis indications for ICU: other

Answer 28

multi-organ failure
uncorrected acidosis
hypothermia

Question 29

incidence endometritis

Answer 29

30% c/s;

1-3% NVD

Question 30

sepsis indications for ICU: resp

Answer 30

pulmonary edema
mechanical ventilation
airway protection

Question 31

metronidazole covers

Answer 31

anaerobes (clostridia, bacteroides, peptostrep)

Question 32

sepsis central ScvO2 target

Answer 32

> 70%

Question 33

mastitis: MRSA strep

Answer 33

vanc + clindamycin

Question 34

probably STSS

Answer 34

meets clinical case definition plus isolation from NON-sterile site

Question 35

incidence GAS

Answer 35

3.3/100 000

Question 36

abx that switches off exotoxin

Answer 36

clindamycin

Question 37

c/s wound infection: MSSA strep

Answer 37

fluclox + clindamycin

Question 38

gram negatives

Answer 38

coliforms, pseudomonas

Question 39

criteria for TSS (staph)

Answer 39

1. fever >39.9
2. rash: diffuse macular edema
3. desquamation, 10-14 days after illness, especially palms and soles
4. hypotension
5. multisystem involvement (>3; ex. conjunctival hyperemia)

Question 40

sepsis CVP target

Answer 40

> 8

Question 41

pyelonephritis - ESBL

Answer 41

gentamicin + meropenem

Question 42

severe sepsis - no focus

Answer 42

meropenem + clindamicin + gentamicin stat

Question 43

definite STSS

Answer 43

meets clinical case definition plus isolation from STERILE site

Question 44

TSSS

Answer 44

fluclox + clindamycin + gentamicin stat

Question 45

TSSS - allergy

Answer 45

vanc + clindamycin + gentamicin stat
OR
linezolid + gentamicin stat

Question 46

% GAS in pharyngitis

Answer 46

10%