sepsis and antibiotics Flashcards

1
Q

mastitis: MSSA strep - allergy

A

vanc + clindamycin

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2
Q

sepsis mixed ScvO2 target

A

> 65%

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3
Q

vanc/teic/linezolid/daptomycin DO cover

A

anaerobes, MRSA, gram positives (staph, GAS, GBS)

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4
Q

mastitis: MSSA streptococci

A

fluclox + clindamycin

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5
Q

sepsis indications for ICU: neuro

A

reduced consciousness

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6
Q

co-amox does not cover

A

MRSA, pseudomonas

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7
Q

TSSS - MRSA

A

vanc + clindamycin + gentamicin stat

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8
Q

gram positives

A

MRSA, staph aureus, GAS, GBS

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9
Q

anaerobes

A

clostridia, bacteroides, peptostreptococci

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10
Q

sepsis indications for ICU: renal

A

dialysis

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11
Q

Carbapenems do not cover

A

MRSA

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12
Q

c/s wound infection: MSSA strep - allergy

A

vancy + clindamycin

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13
Q

endometritis

A

gentamicin stat + cefotaxime + metronidazole

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14
Q

STSS (strep) criteria

A

A - isolation of GAS from sterile or non-sterile site

B - clinical case definition: multi-organ involvement, including hypotension

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15
Q

breast abscess in untreated mastitis

A

3%

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16
Q

c/s wound infection: MRSA strep

A

vanc + clindamycin

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17
Q

first sign of sepsis

A

tachypnea

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18
Q

mastitis: MRSA strep - allergy

A

clindamycin/teicoplanin

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19
Q

sepsis indications for ICU: cardiovascular

A

decreased BP or increased lactate despite fluids

20
Q

sepsis glucose target

A

<8.3

21
Q

incidence of rash in STSS

A

10%

22
Q

endometritis - allergy

A

gentamicin + clindamycin + ciprofloxacin

23
Q

pyelonephritis

A

cefotaxime + gentamicin stat

24
Q

pyelonephritis - allergy

A

gentamicin + ciprofloxacin

25
Q

severe sepsis - no focus - allergy

A

clindamycin + gentmicin + metronidazole + ciprofloxacirn

26
Q

c/s wound infection: MRSA strep - allergy

A

clindamycin/teicoplanin

27
Q

vanc/teic/linezolid/daptomycin do not cover

A

gram negatives (coliform, pseudomonas)

28
Q

sepsis indications for ICU: other

A

multi-organ failure
uncorrected acidosis
hypothermia

29
Q

incidence endometritis

A

30% c/s;

1-3% NVD

30
Q

sepsis indications for ICU: resp

A

pulmonary edema
mechanical ventilation
airway protection

31
Q

metronidazole covers

A

anaerobes (clostridia, bacteroides, peptostrep)

32
Q

sepsis central ScvO2 target

A

> 70%

33
Q

mastitis: MRSA strep

A

vanc + clindamycin

34
Q

probably STSS

A

meets clinical case definition plus isolation from NON-sterile site

35
Q

incidence GAS

A

3.3/100 000

36
Q

abx that switches off exotoxin

A

clindamycin

37
Q

c/s wound infection: MSSA strep

A

fluclox + clindamycin

38
Q

gram negatives

A

coliforms, pseudomonas

39
Q

criteria for TSS (staph)

A
  1. fever >39.9
  2. rash: diffuse macular edema
  3. desquamation, 10-14 days after illness, especially palms and soles
  4. hypotension
  5. multisystem involvement (>3; ex. conjunctival hyperemia)
40
Q

sepsis CVP target

A

> 8

41
Q

pyelonephritis - ESBL

A

gentamicin + meropenem

42
Q

severe sepsis - no focus

A

meropenem + clindamicin + gentamicin stat

43
Q

definite STSS

A

meets clinical case definition plus isolation from STERILE site

44
Q

TSSS

A

fluclox + clindamycin + gentamicin stat

45
Q

TSSS - allergy

A

vanc + clindamycin + gentamicin stat
OR
linezolid + gentamicin stat

46
Q

% GAS in pharyngitis

A

10%