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Repro > Urinary Tract Infections > Flashcards

Urinary Tract Infections Flashcards

1
Q

Bacteriuria?

A

Bacteria in the urine

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2
Q

Pyuria?

A

Pus in the urine

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3
Q

“Significant” Bacteriuria

A

10^5 bacteria in the urine

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4
Q

Dysuria?

A

Pain/buring on urination

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5
Q

Lower UTI?

A

Bladder infections

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6
Q

Urethritis?

A

inflammation of urethra

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7
Q

Pyelonephritis?

A

infection of upper collecting system and kidney

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8
Q

Most common bacterial infection?

A

Urinary Tract Infection

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9
Q

Most common cause of UTI?

A

95% from G.I. Tract –> E. Coli most common

also Staph. saprophyticus

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10
Q

Which sex is more likely to have UTIs as an infant? Why?

A

Males > females

-urinary tract still developing

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11
Q

Which sex is more likely to have UTIs after age 3?

A

Females&raquo_space;» males

Short urethra

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12
Q

Does intercourse lead to higher incidence of bacteriuria?

A

Yes

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13
Q

Does pregnancy increaes the incidence of bacteriuria?

A

Yes

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14
Q

Route of infection?

A 
Ascending Route - >95%
- Urethral trauma
- Intercourse
- Instrumentation
- Diaphragm use
Hematogenous Route - <5%
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15
Q

Mechanisms of infection?

A
  1. Adhesion
  2. Colonization
  3. Invasion
  4. Phase variation
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16
Q

Virulence factors of E. Coli?

A

Adhesions on fimbriae

  • Type 1 fimbriae –> bind to mannose receptors
  • P Fimbraie –> will cause pyelonephritis
17
Q

Give an example of phase variation in E. Coli?

A

After adhering to the uroepithelial wall, E. Coli will shut off Type 1 fimbriae to protect it from PMNs

18
Q

Host defense mechanisms?

A

Bacterial growth inhibition –> High Na+ conc. in urine
Urine Flow –> washes out bacteria
Epithelial Cell Turnover
Antibodies –> IgA

19
Q

Predisposing host factors to UTI?

A 
Urine flow obstruction
Female Factors
Abnormal urine flow
Urethral trauma
Vesiculo-ureteral reflux
instrumentation
General Health

Repro (15 decks)

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