Urinary Tract Infection Flashcards
urinary tract infeciton:
what is it called if the kidney is effected?
Acute Pyelonephritis
Chronic Pyelonephritis
urinary tract infeciton:
what is it called if the bladder is effected?
Cystitis
urinary tract infeciton:
what is it called if the urethra is effected?
Urethritis
urinary tract infeciton:
what is it called if the prostate is effected?
Prostatitis
urinary tract infeciton:
what is it called if the Epididymis/Testis is effected?
Epididymo-orchitis
is it more common in males or femaled?
Female:male 3:1
Affects 30% women at some time
Adults – rarely causes CRF
Children - less common but important cause of CRF
what are general predisposing factors?
General factors which make an individual more susceptible to UTI (or other infection) include:
Immunosuppression
Steroids
Malnutrition
Diabetes
What are some Predisposing Factors Specific to the Urinary Tract?
Female sex (short urethra)
Sexual intercourse and poor voiding habits
Congenital abnormalities e.g. duplex kidney
Stasis of urine e.g. due to poor bladder emptying
Foreign bodies eg catheters, stones
Oestrogen deficiency in postmenopausal women
Fistula between bladder & bowel
what is the pathogenesis?
• Usually bowel organisms - E coli, Proteus, Klebsiella, Enterococcus
Transfer:
- Transurethral route
- Perurethral area contaminated - Recurrent UTIs, diaphragms, ? bubble baths
- Urethra to bladder - Intercourse, catheterisation
- Bladder (and up ureters)
- Bloodstream
- Lymphatics
what are the clinical features in a child?
- Diarrhoea
- Excessive crying
- Fever
- Nausea and vomiting
- Not eating
what are the clinical featues in an adult?
- Flank pain
- Dysuria (“like passing broken glass”)
- Cloudy offensive urine
- Urgency
- Chills
- Strangury
- Confusion (very old people)
What are the Clinical features of acute pyelonephritis?
- Pyrexia
- Poor localisation
- Loin tenderness (renal angle)
- Signs of dehydration
- Turbid urine
what investigations may be done?
- Mid-stream sample of urine
- Urinalysis In ward - Blood, leucocytes, protein and nitrites
- Microbiology In laboratory
- Microscopy and Gram staining
- Bacteruria >105 CFU /ml
Culture and sensitivity
what is the management?
The principles of management are:
- Identify the infecting organism & institute appropriate treatment
- Identify predisposing factors and treat if possible
what is the treatment?
- Fluids
- Antibiotics:
Amoxicillin (3-5 day course or 3g x 2), cephalosporin
Trimethoprim
•Severe infections - Intravenous antibiotics