Urinary System - Module 16 Flashcards
Urinary System
Organs of Urinary System
Kidney
Ureter
Urinary Bladder
Urethra
Vein that carries cleaned blood from kidney back to heart
Renal Vein
Main Artery that brings blood with waste from heart
Renal Artery
Functions of Kidney
- Regulation of Ionic composition
- Regulation of Blood pH, Osmolarity, Glucose
- Regulation of Blood Volume
- Regulation of Blood Pressure
- Release of Erythropoietin
- Waste excretion
Organization of Kidney Parenchyma
Cortex and Medulla, Lobe and Lobules
Structural and Functional unit of the kidney
Nephron
5 parts of Nephron
- Renal Corpuscle
- Proximal (Straight and Convoluted)
- Loop of Henle
- Distal (Straight and Convoluted)
- Collecting Duct
What comprises the Renal Corpuscle
Glomerulus and Bowman’s Capsule
This is a cluster of Blood Vessels in Renal Corpuscle
Glomerulus
Is a double walled envelope structure of Renal Corpuscle
Bowman’s Capsule
What is produced by the Renal Corpuscle
Glomerular Ultrafiltrate
Efferent arterioles leaves the glomerulus at _____________
Vascular Pole
Ultra filtrate leaves corpuscle at _____________
Renal Pole
True or False, capillaries forming glomerulus are not fenestrated
False, it is fenestrated
Bowman’s capsule is comprised of Visceral and Parietal layers, what is the lining of Parietal layers
Simple Squamous Cells
Bowman’s capsule is comprised of Visceral and Parietal layers, what makes up the lining of Visceral layers
Podocytes
What constitutes the connective tissue stroma of the glomerulus
Mesangial Cells
This part of the nephron reabsorbs water, nutrients and solids
Proximal Convoluted Tubules
Lining of Proximal Convoluted Tubules
Simple Cuboidal Epithelium
True or False, Tubule cells have villi on their luminal surfaces
False, they have Microvilli
True or False, Tubule cells appear STRIATED due to numerous basal infoldings and mitochondria
True
This functions as a counter current multiplier system that determines osmolarity of urine
Loop of Henle
Segments of Loop of Henle/Medullary Loop
Descending Limb
Thin Segment
Ascending Limb
What is the epithelia lining of the thin segment of Medullary loop
Simple Squamous Epithelium
This part’s reabsorption is regulated by ADH and Aldosterone
Distal Convoluted Tubule
Epithelia lining of Distal Convoluted Tubule
Simple Cuboidal Epithelium
True or False, Distal convoluted tubules lacks microvilli and is non striated
False, they are striated
Formed where the ascending loop of Henle/DCT contacts the afferent arteriole of Renal Corpuscle
Juxtaglomerular Apparatus
Cells of the Juxtaglomerular Apparatus
- Macula densa cells of DCT
- Juxtaglomerular cells of afferent arteriole
- Extraglomerular Mesangial Cells
What is produced by the Juxtaglomerular Apparatus that converts angiotensinogen to angiotensin
Renin
What structure drains urine from Nephron to Renal Pelvis
Collecting Duct
2 cells types of Collecting Duct
Cuboidal in Cortical Part, Columnar in Medullary
Epithelium lining of Ascending limb of Loop of Henle
Simple Cuboidal
Epithelium lining of Descending Limb of Loop of Henle
Simple Squamous
Total pressure that promotes filtration
Net Filtration Pressure
Glomerular Blood Hydrostatic Pressure (GBHP)
55 mmHg
Capsular Hydrostatic Pressure (CHP)
15 mmHg
Blood Colloid Osmotic Pressure
30 mmHg
Net Filtration Pressure
10 mmHg
True or False, Changes in net filtration doesn’t affect Glomerular Filtration Rate
False, it affects GFR
Filtration stops if arterial pressure drops to _____ mmHg
45 mmHg
GFR functions normally at _____ mmHg arterial pressure
80 to 180 mmHg
These are Cells that senses Sodium levels located at Distal Convoluted Tubules
Macula densa
Forms Connections via actin and microtubules for selective vasoconstriction and vasodilation
Extraglomerular Mesangial Cells
Other term for Extraglomerular Mesangial Cells
Lacis Cells
Functions of Juxtaglomerular Apparatus
Afferent and Efferent Arteriolar Feedback Mechanism
Angiotensinogen from liver catalyzed by renin to become ________________
Angiotensin I
What constricts the Blood Vessels all over the body to increase systemic blood pressure and maintain blood pressure in Glomerulus to maintain GFR
a. Angiotensinogen
b. Angiotensin I
c. Angiotensin II
C. Angiotensin II
What hormone counteracts the Renin-Angiotensin-Aldosterone System (RAAS)
Atrial Natriuretic Peptide
What structure conducts urine from kidney to urinary bladder
Ureter
3 layers of Ureter
T. mucosa, T. muscularis, T serosa/adventitia
Layer of ureter that is lined by 5-6 cell layer of transitional epithelium
T. mucosa
4 layers of Urinary Bladder and Urethra
T. mucosa, T. submucosa, T. muscularis, T. serosa/adventitia
What epithelium lines the external urethral orifice
Stratified Squamous