Urinary System Flashcards

1
Q

Adult male kidney weight
Blood volume filtered
Kidney failure&raquo_space;
Nerve of kidney

A

125g
200L or 125ml/min
Dialysis
Renal plexus

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2
Q

Tube from kidney

A

Ureter

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3
Q

Structure and function unit of kidney

A

Nephrons

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4
Q

Afferent vs efferent

A

Afferent towards bowmans capsule(vascular pole)
Efferent towards body(renal pole)

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5
Q

Renal corpuscle is formed of

A

Glomerulus (blood vessels)
Bowmans capsule( double walled envelope)

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6
Q

Capillaries in glomerulus are..

A

Fenestrated
Rest on thick basal lamina (filtration slits and pedicles of podocytes)

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7
Q

Bowmans capsule epithelium

A

Inner visceral» podocytes
Outer parietal&raquo_space; simpla swuamous

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8
Q

Connective tissue of kidney is

A

Mesangial cells
Fix arterioles and support

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9
Q

What stimulates absorption in distal convoluted tubules

A

ADH
Aldosterone

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10
Q

Has microvilli and many mitochondria and straited

A

Proximal convoluted tubule
Both are striated due to basal foldings

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11
Q

Drain urine from nephron to renal pelvis

A

Collecting tubule

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12
Q

Many collecting tubules»…»

A

Papillary duct
Renal pelvis

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13
Q

Urine formation steps

A

1 glomerular filtration (GFR)
2 tubular reabsorption
3 tubular secretion

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14
Q

GFR
High
Low

A

Glomerular filtration rate
No proper reabsorption, in urine
Toxic accumulation

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15
Q

Tubular secretion

A

Branch from efferent arteriole to collecting duct with toxic chemicals to prevent harm to nephron

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16
Q

Creatinine vs creatine
Amount

A

Creatine&raquo_space; beneficial , high energy phosphate storage
Creatinine» toxic byproduct
Healthy kidney = 0.6-1.2 mg/dl

17
Q

Amyloidosis symptoms

A

Enlarged kidney
Thickened cortex with amyloid deposits
Blurred medulla

18
Q

What is amyloidosis

A

2ndry structure of protein instead of alpha&raquo_space; beta
Resist digestion
Accumulate as inclusion

19
Q

Inclusions of amyloidosis staining

A

Iodine&raquo_space; brown
Congo red» pink (white light)&raquo_space; green(polarised light)

20
Q

Amyloidosis chemical nature

A

AL&raquo_space; light chain, immunoglobins with light chain, synthesised from plasma cell
AA»fibril, chronic inflammation, synthesised in liver