urinary system Flashcards

1
Q

what are the functions of the urinary system

A
  • Filter blood
  • Regulate blood volume
  • Regulate concentration of blood solutes
  • Regulate pH of extracellular fluid
  • Regulate blood cell synthesis
  • Synthesis in the active form of vitamin D
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2
Q

what is the external anatomy of the kidney

A

renal capsule, perirenal fat, renal fascia, hilum

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3
Q

what is the internal anatomy of the kidney

A

cortex, medulla, calyces, renal pelvis, ureter

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4
Q

what is the functional unit of the kidney

A

nephron

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5
Q

what are the parts of the nephron

A

i. Renal corpuscle
ii. Proximal convoluted tubule
iii. Loop of henle
iv. Distal convoluted tubule
v. Collecting ducts

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6
Q

What is the order of urine formation in the nephron?

A

Nephron, renal pelvis, ureters, urinary bladder, urethra

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7
Q

Name the 3 processes by which urine formation is categorized

A

1.golumlar Filtration
2.Tubular reabsorption
3.Tubular secretion

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8
Q

What is filtrate

A

it is the pre form of urine, but when it exists the body it is called urine

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9
Q
  1. Filtration pressure determines
A

the amount of filtrate formed

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10
Q

What is the glomerular filtration rate

A

The volume of filtrate formed by both kidneys per min

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11
Q

what is the bowmans capsule

A
  • Enlarged end of the nephron
  • Indented to form a double-walled chamber
  • Surround glomerulus
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12
Q

what is the glomerular capillary

A
  • Network of capillaries
  • Blood enters afferent arteriole
  • Exits efferent arteriole
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13
Q

what is a podocyte

A

these wrap around the glomerular capillaries

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14
Q

what is the main function of the juxtaglomerular apparatus

A

Releases renin which regulates blood pressure
- main site of renin production

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15
Q

Juxtaglomerular cells

A

ring of smooth muscle that lines the afferent arteriole entering bowmans capsule, Secretes renin which is important in regulation of blood pressure

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16
Q

Macular densa

A

specialized tubule cells of the distal convoluted tubule, responds to changes in the sodium chloride levels in the distal convoluted tubule

17
Q

Which part of the nephron is involved during tubular reabsorption

A

Peritubular capillaries

18
Q

Major site of reabsorption

A

proximal convoluted tubule

19
Q

How do solutes transport through the nephron during the reabsorption

A

Solutes are transported by active transport and co transport

20
Q

how is water get transported

A

through osmosis

21
Q

ascending loop of Henle in tubular reabsorption

A

impermeable to water but still permeable to solutes
- The water stays in the filtrate
- Not allowing water or solute to pass through

22
Q

descending loop of Henle in tubular reabsorption

A

water exits osmosis and solutes enter
- Permeable to water (squamous cells)
- Additional 15% of filtrate volume is reabsorbed

23
Q

How does diabetes impact filtrate volume? In other words, do diabetes patients produce higher volume of filtrate or lower volume of filtrate?

A
  • People with diabetes cannot reabsorb 100% of glucose because the concentration of glucose in the filtrate exceeds the capacity of transporters. Not enough transport proteins to take enough glucose back
  • Glucose in the filtrate draws water into the convoluted tubule which increases filtrate volumes
24
Q

What is tubular secretion

A

Solutes are secreted from the blood into the filtrate

25
Q

where does tubular secretion take place in the nephron

A

distal convoluted tubule

26
Q

Give examples on what types of solutes or substances can be secreted directly into filtrate?

A

Urea, creatinine, sulfates, phosphates and nitrates

27
Q

Renin-angiotensin-aldosterone

A

Stimulated by low blood pressure. Changes of the blood pressure will send signal to juxtaglomerular cells to secrete an enzyme aldosterone.

28
Q

ADH

A

Stimulated by decreased blood pressure or increased blood osmolality.

29
Q

What are the 2 common substances that can affect ADH release? What happens if ADH is blocked?

A

Caffeine and alcohol

30
Q

glomerular filtration

A

movement of substances from the blood within the glomerelus into the capsular space

31
Q

tubular reabsorption

A
32
Q

tubular secretion

A