Urinary Drugs

Question 1

Phenazopyridine

Answer 1

• PO use only
• MOA: local anesthetic of mucosa of urinary tract, relives pain, burning, frequency/urgency secondary to cystitis
• Side effects/adverse reactions: red/orange urine, nephrotoxicity, hepatotoxicity, hemolysis

Question 2

Bethanechol

Answer 2

• Urinary stimulant
• Group: direct acting parasympthomimetic
• Indication: hypotonic bladder, urinary retention, neurogenic bladder
• MOA: increase tone of detrusor muscle
• Contraindication: peptic ulcer
• Side effects: GI distress, dizziness, fainting
• Must take on an empty stomach

Question 3

Oxybutynin

Answer 3

• Urinary antispasmodic
• MOA: anticholinergic, relaxes detrusor muscle to relieve bladder spasms
• Indication: overactive bladder, neurogenic bladder
• Contraindication: glaucoma, prostate problems (BPH)
• Side effects: dry mouth, tachy, dizziness, fainting, blurred vision, constipation