Hypotension

Question 1

Midodrine

Answer 1

• Mechanism of Action: alpha-1 agonist –> vasoconstriction
• Contraindication: AKI
• Side effects, Adverse reactions:
  
  • Urinary retention (BPH)
  • Supine HTN (HTN associated with lying supine, check BP & administer while patient in supine position)
• Medication Administration: PO, IV

Question 2

Symptomatic Hypotension

Answer 2

• Usually treated with:
  
  • Crystalloid (NS)
  • Colloid volume expander (albumin) if edematous
• During hypovolemic shock (medical emergency)
  - Vasopressin (Pitressin)=ADH
  
  • Dobutamine (Dobutrex) (beta-1 agonist) see HF slides
  • Emergency drugs, used for shock and cardiopulmonary resuscitation (discussed in Endocrine)