Urinary Flashcards

1
Q

What are indications for renal u/s?

A
  • UTI
  • palpable mass
  • elevated creatinine & or BUN
  • severe flank pain
  • hematuria
  • decrease urine output
  • assessment for renal mass seen on CT/IVP
  • non visualized kidney
  • trauma
  • post surgical complications
  • biopsy/drainage
  • hypertension
  • diabetes
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2
Q

Symptoms of a renal infection or disease process:

A
  • flank pain
  • hematuria
  • polyuria
  • oliguria
  • fever
  • urgency
  • weightloss
  • general edema
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3
Q

What is urinalysis essential for detecting?

A

urinary tract disorders in pts. whose renal function is impaired or absent

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4
Q

Hematuria is

A

RBC in the urine

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5
Q

Pyuria is

A

Pus in urine

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6
Q

Urine pH is important in managing

A

diseases such as bacteriauria and renal calculi

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7
Q

pH referes to what?

A

strength of urine as partly acidic or alkaline solution

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8
Q

The abundance of hydrogen ions in the urine is called:

A

pH

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9
Q

When is urine acidic?

A

if it contains an increased concentration of hydrogen ions

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10
Q

The formation of renal calculi partly depends on :

A

pH of urine

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11
Q

What are associated with alkaline urine?

A

Renal tubular acidosis and chronic renal failure

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12
Q

What is specific gravity?

A

measurement of the kidney’s ability to concentrate urine (concentration factor depends on the amount of dissolved waste products)

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13
Q

Specific gravity is esp. low in cases of:

A

renal failure
glomerulonephritis
pylonephritis
(these cause renal tubular damage, affecting kidney’s ability to concentrate urine)

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14
Q

What can hematuria be associated with?

A

early renal disease

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15
Q

An abundance of RBC in the urine may suggest:

A
  • renal trauma
  • neoplasm
  • calculi
  • pyelonephritis
  • glomerular inflammatory process
  • vascular inflammatory process
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16
Q

When may leukocytes present?

A

with inflammation, infection or tissue necrosis originating from anywhere in the urinary tract

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17
Q

What is hematocrit?

A

relative ratio of plasma to packed cell volume in blood.

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18
Q

Decreased hematocrit occurs with

A

acute hemorrhagic processes secondary to disease or blunt trauma

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19
Q

When is hemoglobin present in urine?

A

When there is extensive damage or destruction of the functioning erythrocytes (injures the kidney and can cause acute renal failure)

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20
Q

Albuminuria is commonly found with

A

benign and malignant neoplasms, calculi, chronic infections, pyelonephritis

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21
Q

Measurements of creatinine are an index for determining what?

A

glomerular filtrations rate

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22
Q

T/F: blood serum creatinine levels are said to be more specific and more senstive

A

T

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23
Q

Creatinine is a byproduct of

A

muscle energy metabolism

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24
Q

A decreased creatinine clearance indicates

A

renal dysfunction because creatinine blood levels are constant and only decreased renal function prevents normal excretion of creatine

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25
Q

Creatinine elevated with

A
  • diabetes
  • renal function
  • acute tubular nephrosis
  • pylonephritis
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26
Q

Creatinine decreased with

A
  • debilitation
  • starvation
  • hyperthyroidism
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27
Q

What is Blood Urea Nitrogen (BUN)?

A

the concentration of urea nitrogen in blood and is the end product of cellular metabolism (relative to the degree of renal impairment and rate of urea excreted by kidneys)

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28
Q

BUN elevated with:

A
  • renal damage
  • renal failure
  • dehydration
  • chronic or acute renal disease
  • urinary obstruction
  • GI bleed
  • CHF
  • shock
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29
Q

BUN decreased with:

A
  • overhydration
  • pregnancy
  • liver failure
  • secondary to smoking
  • decrease protein intake
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30
Q

Types of Renal Cystic Disease

A
  • simple renal cyst
  • polycystic renal disease
  • multicystic dysplastic kidney
  • medullary sponge kidney
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31
Q

How often do simple renal cysts occur?

A

common, 50% of adults over 50 years

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32
Q

Where may simple renal cysts be found?

A

anywhere in the kidney

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33
Q

When are simple renal cysts clinically significant?

A

when they distort the adjacent calyces or produce hydronephrosis or pain

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34
Q

Son findings of simple renal cysts:

A

cystic properties
no septations
cyst may have a cyst or mass within it

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35
Q

Polycystic renal disease may present in two forms:

A
  • autosomal-recessive form

- autosomal-dominant form

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36
Q

What is autosomal-recessive polycystic kidney disease (ARPKD)?

A
  • fairly rare
  • dilation of the renal collecting tubules which causes renal failure and in the later forms there is also liver involvement
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37
Q

Four forms of ARPKD?

A

-perinatal
-neonatal
-infantile
-juvenile
(the earler the symptoms manifest, the less the kidneys are functioning)

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38
Q

Son. findings of perinatal form of ARPKD?

A
  • oligohydramnios

- enlarged echogenic kidneys

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39
Q

Son. findings of later forms of ARPKD?

A
  • enlarged kidneys
  • echogenic cortex and medulla
  • lack of coritocmedullary differentiation
  • may be macroscopic cysts (1-2mm) located in the medulla
  • in children there may be also hepatic fibrosis and splenomegaly
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40
Q

What is Autosomal-dominant polycystic kidney disease (ADPKD)?

A
  • common genetic disease in women and men

- bilateral disease characterized by multiple cysts located in the renal cortex and medulla

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41
Q

T/F: ADPKD cysts vary in size and may be asymmetrical?

A

T

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42
Q

When does ADPKD manifest?

A
  • not until 4th or 5th decade of life

- by age 60, 50% will have end stage renal disease

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43
Q

Symptoms of ADPKD: 7

A
  • pain
  • hypertension
  • palpable mass
  • hematuria
  • headache
  • UTI
  • renal insufficiency
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44
Q

Complications of ADPKD:

A
  • infection
  • hemorrhage
  • stone formation
  • rupture of cysts
  • renal obstruction
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45
Q

Associated abnormalities of ADPKD:

A
  • cysts in liver, spleen, pancreas, thyroid, ovary, testes, breast
  • cerebral berry aneurysm (Circle of Willis) cerebral arteries
  • increased incidence of renal cell carcinoma
  • AAA
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46
Q

Statistics of Cerebral Berry Aneurysm

A

16% have it, 9% die from rupture

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47
Q

Sonographic findings of ADPKD in the fetus:

A
  • moderately enlarged hyperchoic kidneys
  • increased corticomedullary differentiation
  • further screening necessary
  • not compatible with life
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48
Q

Sonographic findings of ADPKD in adults:

A
  • bilateral renal enlargement
  • multiple cysts in both cortex and medulla
  • advanced cases-normal parenchyma replaced with multiple cysts and kidneys lose shape
  • cysts may grow large enough to obliterate renal sinus
  • internal debris in cysts
  • Walls of cysts may calcify, stones may form within cysts
  • complicated cysts may result in spontaneous bleeding
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49
Q

What is multicystic dysplastic kidney?

A

non hereditary renal dysplasia that usually occurs unilaterally

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50
Q

What is the most common form of cystic disease in neonates?

A

multicystic dysplastic kidney

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51
Q

T/F: bilateral disease of multicystic dysplastic kidney is incompatible with life?

A

True

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52
Q

Complications of multicystic dysplastic kidney:

A
  • hypertension
  • hematuria
  • infection
  • flank pain
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53
Q

Son. finding of multicystic dysplastic kidney in neonates and children:

A

-kidneys appear enlarged

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54
Q

Son findings of multicystic dysplastic kidney in adults:

A
  • kidneys small and calcified

- multiple cysts varying in size with no normal renal parenchyma

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55
Q

What is medullary sponge kidney?

A
  • rare, non-hereditary benign renal disease

- congenital but may not be diagnosed until adulthood

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56
Q

What is medullary sponge kidney associated with?

A

dilated collecting tubules and cysts that form in the medulla

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57
Q

Son findings of of medullary sponge kidney:

A
  • medulla is very echogenic

- may have associated calcium stones (nephrocalcinosis)

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58
Q

What is medullary nephrocalcinosis?

A
  • calcium that forms in the medullary pyramids

- hyperechoic medullary pyramids with or without shadowing

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59
Q

What is medullary nephrocalcinosis associated with?

A
  • medullary sponge
  • hyperparathyroidism
  • cushing syndrome
  • adrenal gland tumors
  • oral pharmocological doses of vitamin E, calcium, steroid use and malignant neoplasms
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60
Q

T/F: sonographic appearance of renal masses is specific

A

False, nonspecific

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61
Q

What is the first finding suggesting a mass may be present?

A

abnormal contour

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62
Q

List malignant renal masses:

A
  • renal cell carcinoma
  • transitional cell carcinoma
  • Wilm’s tumor
  • renal lymphoma
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63
Q

What is most common of all renal tumors, (85%)?

A

renal cell carcinoma

64
Q

Renal cell carcinoma, AKA:

A

adenocarcinoma or hypernephroma

65
Q

Who is renal cell carcinoma likely to affect?

A
  • twice as common in males as females

- 6th decade of life

66
Q

T/F: If caught early, prognosis for renal cell carcinoma is good?

A

True

67
Q

Clinical symptoms of renal cell carcinoma:

A
  • nonspecific
  • hematuria
  • flank pain
  • palpable mass
68
Q

Staging of renal cancer uses the

A

Robson system

69
Q

Sonographic findings of renal cell carcinoma

A
  • most are unilateral
  • isoechoic, hypoechoic solid mass
  • may be complex due to areas of necrosis
70
Q

Stage 1 of renal cell carcinoma

A

confined to the kidney

71
Q

Stage 2 of renal cell carcinoma

A

spread to the perinephric fat but within Gerota’s fascia

72
Q

Stage 3 A of renal cell carcinoma

A

perinephric involvement with spread to renal vein and or IVC

73
Q

Stage 3 B of renal cell carcinoma

A

perinephric with regional lymph node enlargement

74
Q

Stage 3 C of renal cell carcinoma

A

perinephric involvement with venous and lymph node involvement

75
Q

Stage 4 of renal cell carcinoma

A

invasion of adjacent structures, distal metastasis

76
Q

Where does transitional cell carcinoma originate from?

A

the transitional epithelial lining of the urinary tract system

77
Q

Transitional cell carcinoma is more common in

A

males, usually after 60 years old

78
Q

Symptoms of transitional cell carcinoma

A
  • painless hematuria

- blood clots

79
Q

Son. findings of transitional cell carcinoma:

A
  • most commonly seen in the bladder, but can be anywhere in urinary system
  • bladder tumors found in trigone area and the lateral borders of bladder
  • bladder tumors are focal non mobile masses within the bladder lumen
  • masses in renal pelvis are more easily ID’d than those in the renal sinus
80
Q

What is squamous cell carcinoma?

A
  • rare, highly invasive tumor

- poor prognosis

81
Q

Clinical symptoms of squamous cell carcinoma:

A

hx of chronic irritation and gross hematuria

-palpable kidney secondary to severe hydronephrosis

82
Q

Son findings of squamous cell carcinoma

A
  • large mass in the renal pelvis

- obstruction from kidney stones

83
Q

What is renal lymphoma?

A
  • usually a secondary process due to lymphoma

- large renal masses that can be numerous and bilateral

84
Q

Renal lymphoma is more common in

A

non-Hodgkin’s lymphoma

85
Q

Clinical symptoms of renal lymphoma

A
  • uncommon
  • hematuria
  • fever
  • flank pain
  • palpable mass
86
Q

Sonographic findings of renal lymphoma

A
  • variety of appearances, depends on location
  • hypoechoic structures with poor acoustic enhancement
  • may exhibit numerous thin septa
  • renal parenchyma may exhibit a diffuse hypoechoic pattern because of diffuse infiltration
87
Q

Wilms’ tumor AKA

A

nephroblastoma

88
Q

What is the most common solid renal mass of childhood?

A

Wilms’ tumor/ nephroblastoma

89
Q

When is Wilm’s tumor common?

A

rare in newborn, peaks in second year of life

90
Q

Clinical symptoms of Wilms’ tumor?

A
  • palpable mass
  • pain
  • anorexia
  • nausea
  • vomiting
  • fever
  • gross hematuria
91
Q

Son findings of Wilms’ tumor

A
  • large flank masses
  • well circumscribed
  • homogenous
  • hypoechoic
  • may be complex due to necrosis
  • hypertension
92
Q

Son findngs of angiomyolipoma

A
  • brightly echogenic, may have posterior enhancement
  • found in cortex
  • tendency to hemorrhage (highly vascular)
93
Q

What do lipomas consist of?

A

fat cells

94
Q

Are lipomas more common in females or males?

A

females

95
Q

Clinical symptoms of lipoma

A
  • asymptomatic

- may cause hematuria

96
Q

Son findings of lipomas

A

well defined echogenic mass

97
Q

What do oncocytomas consist of?

A

large epithelial cells

98
Q

Oncocytomas are found most often in

A

older men, occur in the parathyroid glands, thyroid and adrenal glands

99
Q

Symptoms of oncocytomas:

A

typically asymptomatic, but tumor may cause pain and hematuria

100
Q

Son findings of oncocytomas

A

“spoke-wheel” pattern

101
Q

Mesoblastic nephroma AKA

A

fetal renal hematoma, a benign counterpart of Wilms tumor

102
Q

What is the most common solid neoplasm in the neonate?

A

mesoblastic nephroma

103
Q

Is mesoblastic nephroma found more often in men or women?

A

men

104
Q

What two abnormalities are associated with mesoblastic nephroma?

A

large flank mass, hypertension

105
Q

Issues associated with renal disease

A
  • generalized increase in cortical echoes which are a result of deposits of collagen and fibrous tissues
  • interstitial nephritis
  • acute tubular necrosis
  • amyloidosis
  • diabetic nephropathy
  • systemic lupus erythematosus
  • myeloma
  • loss of normal anatomic detail
  • chronic pyelonephritis
  • tubular ectasia
  • acute bacterial nephritis
106
Q

Endstage renal disease often results in

A

renal atrophy (seen on u/s by measuring renal length and cortical thickness

107
Q

What acute diseases can produce renal enlargement and decreased parenchymal echogenicity?

A
  • renal vein thrombosis
  • pyelonephritis
  • renal transplant rejection
108
Q

What is acute pyelonephritis?

A

Upper UTI, resulting from ascending infection through the ureters

109
Q

Acute pyelonephritis most affects women of what age?

A

of childbearing age

110
Q

Symptoms of pyelonephritis include:

A
  • sudden onset of flank pain
  • fever
  • frequency
  • hematuria
  • dysuria
111
Q

When can a clinical diagnosis for acute pyelonephritis be made?

A

when urinalysis indicates abnormal bacteria, leukocytes, and RBC

112
Q

Son findings of acute pyelonephritis

A
  • difficult to diagnose son.
  • kidneys may be completely normal or slightly enlarged
  • dilated blunt calyx
  • loss of corticomedullary differentiation
113
Q

What does chronic pyelonephritis result from?

A

recurrent or untreated UTI’s (more common in women)

114
Q

Chronic pyelonephritis may result in

A

loss of kidney function over time (renal dialysis or transplant may be warranted.)

115
Q

Clinical symptoms of chronic pyelonephritis include:

A
  • fatigue
  • hypertension
  • flank pain
  • hematuria
116
Q

Son findings of chronic pyelonephritis:

A
  • dilated blunt calyces
  • cortical thinning
  • if disease is unilateral , the contralateral kidney may enlarge to compensate
117
Q

What does renal failure disallow?

A

normal removal of accumulated metabolites from blood

118
Q

Pre nenal causes of renal failure:

A
  • loss of profusion due to thrombosis
  • shock
  • sepsis
  • embolization
  • heart failure
119
Q

Intra renal causes of renal failure:

A
  • parenchymal disease
  • chronic infections
  • renal ischemia
  • AIDS
  • Exposure to toxins
120
Q

Post renal causes of renal failure:

A
  • obstructive uropathy
  • increase incidence with uncontrolled diabetes
  • uncontrolled hypertension
121
Q

Lab tests that find renal failure:

A
  • Elevated BUN creatinine
  • Decrease serum calcium
  • low urinary specific gravity
  • proteinurea
  • RBC and WBC in urine
  • anemia
122
Q

Son findings of renal failure

A
  • decrease renal size

- increase parenchymal echogenicity-fibrosis and scarring

123
Q

What are renal stones made of?

A
  • calcium
  • uric acid
  • xanthine
  • cystine
124
Q

Renal stones AKA:

A

urolithiasis

125
Q

Majority of renal stones are made with

A

Calcium

126
Q

T/F: Renal stones may be found anywhere in the urinary system?

A

True

127
Q

What demographics have higher instances of renal stones?

A
  • men

- U.S.

128
Q

Staghorn calculi:

A

when stones fill the entire collecting system and become a solid mass

129
Q

As stones pass thru the ureter they usually become lodged where?

A

at the renal pelvis and ureterovesicle junction causing excruciating pain

130
Q

If pain is localized in the flank area, where is the stone likely located?

A

the kidney or proximal ureter

131
Q

Clinical symptoms of renal stones

A
  • hematuria
  • RBC in urine
  • WBC in urine
  • bacteria in urine
132
Q

Treatment for renal stones depends on size and location:

A
  • lithotripsy
  • percutaneous nephrolithotomy
  • ureteroscopic stone removal
133
Q

If stones cause obstruction there will be :

A

hydronephrosis and depending on the location the ureter may be dilated superiour to the level of obstruction

134
Q

Son findings of renal stones

A
  • very echogenic

- sharp, marginated, clean shadows

135
Q

What is hydronephrosis?

A

dilation of the renal pelvis and calyces caused by an obstruction of the urinary tract..if obstruction is at the level of the urethra then bilateral hydronephrosis will occur

136
Q

Causes of bilateral hydronephrosis:

A
  • stones lodged in urethra
  • enlarged prostate
  • bladder tumors
  • posterior urethral valve syndrome in infants and young boys
137
Q

Causes of unilateral hydronephrosis

A
  • congenital disorders
  • acquired syndromes
  • tumors
  • inflammatory disorders
  • blood clots
  • pregnancy
  • stones
138
Q

With hydronephrosis, if obstruction is not corrected, severe deterioration of what may occur?

A

renal cortex

139
Q

Hydronephrosis clinical symptoms:

A
  • flank pain
  • nausea
  • vomiting
  • elevated BUN and creatinine
140
Q

Sonographic findings for hydronephrosis:

A

-hypoechoic /cystic area within the renal sinus

141
Q

Grade 1 of hydronephrosis:

A

small separation of calyceal pattern

142
Q

Grade 2 of hydronephrosis

A

bear-claw effect, with fluid extending into the major and minor calyceal system and thinning of the renal parenchyma

143
Q

Grade 3 of hydronephrosis

A

massive dilation of the renal pelvis with loss of renal parenchyma

144
Q

Trauma in the kidneys:

A

linear absence of echoes in area of traumatized kidney

145
Q

Renal infarction is usually caused by:

A

RA obstruction

146
Q

Results of renal infarction:

A
  • kidney reduced in size

- complete occlusion/multiple infarcts results in small hyperechoic endstage appearing kidney

147
Q

Renal abscess AKA:

A

renal carbuncle

148
Q

Clinical symptoms of abscess:

A
  • fever
  • leukocystosis
  • flank pain
149
Q

Perforation of renal abscess in surrounding area

A
  • marked fever

- abdomen board-like rigidity with flank pain

150
Q

Where does a renal transplant go?

A

right side of pelvis within retroperitoneum

151
Q

Indications for renal transplant:

A
  • vascular compromise
  • renal failure
  • infection
152
Q

Lymphocele

A
  • predominantly anechoic mass 4-8 weeks post transplant
  • can contain septations/debris
  • can cause obstruction when large
  • can be drained, may reoccur
153
Q

Urinoma:

A

post-op complication with in first 2 weeks-ureter anastimosis leak

154
Q

Hematoma for renal transplant

A

arise soon after surgery

  • new-anechoic
  • old-hyperechoic
  • contain debris
155
Q

Son findings of acute rejection of renal transplant:

A
  • enlarged kidney
  • decreased cortical echogenicity
  • indistinct corticomedullary boundaries
  • prominent hypoechoic pyramids
  • peri-transplant fluid collections
156
Q

Severe rejection of renal transplant result in :

A
  • marked hemorrhage in parenchyma
  • high-resistive waveforms, decreased, absent, or reversed end diastolic flow, >0.7
  • Acute tubular necrosis
  • renal artery thrombosis
  • RV thrombosis
  • Urinary obstruction
  • cyclosporing toxicity