Urinary Flashcards
What are indications for renal u/s?
- UTI
- palpable mass
- elevated creatinine & or BUN
- severe flank pain
- hematuria
- decrease urine output
- assessment for renal mass seen on CT/IVP
- non visualized kidney
- trauma
- post surgical complications
- biopsy/drainage
- hypertension
- diabetes
Symptoms of a renal infection or disease process:
- flank pain
- hematuria
- polyuria
- oliguria
- fever
- urgency
- weightloss
- general edema
What is urinalysis essential for detecting?
urinary tract disorders in pts. whose renal function is impaired or absent
Hematuria is
RBC in the urine
Pyuria is
Pus in urine
Urine pH is important in managing
diseases such as bacteriauria and renal calculi
pH referes to what?
strength of urine as partly acidic or alkaline solution
The abundance of hydrogen ions in the urine is called:
pH
When is urine acidic?
if it contains an increased concentration of hydrogen ions
The formation of renal calculi partly depends on :
pH of urine
What are associated with alkaline urine?
Renal tubular acidosis and chronic renal failure
What is specific gravity?
measurement of the kidney’s ability to concentrate urine (concentration factor depends on the amount of dissolved waste products)
Specific gravity is esp. low in cases of:
renal failure
glomerulonephritis
pylonephritis
(these cause renal tubular damage, affecting kidney’s ability to concentrate urine)
What can hematuria be associated with?
early renal disease
An abundance of RBC in the urine may suggest:
- renal trauma
- neoplasm
- calculi
- pyelonephritis
- glomerular inflammatory process
- vascular inflammatory process
When may leukocytes present?
with inflammation, infection or tissue necrosis originating from anywhere in the urinary tract
What is hematocrit?
relative ratio of plasma to packed cell volume in blood.
Decreased hematocrit occurs with
acute hemorrhagic processes secondary to disease or blunt trauma
When is hemoglobin present in urine?
When there is extensive damage or destruction of the functioning erythrocytes (injures the kidney and can cause acute renal failure)
Albuminuria is commonly found with
benign and malignant neoplasms, calculi, chronic infections, pyelonephritis
Measurements of creatinine are an index for determining what?
glomerular filtrations rate
T/F: blood serum creatinine levels are said to be more specific and more senstive
T
Creatinine is a byproduct of
muscle energy metabolism
A decreased creatinine clearance indicates
renal dysfunction because creatinine blood levels are constant and only decreased renal function prevents normal excretion of creatine
Creatinine elevated with
- diabetes
- renal function
- acute tubular nephrosis
- pylonephritis
Creatinine decreased with
- debilitation
- starvation
- hyperthyroidism
What is Blood Urea Nitrogen (BUN)?
the concentration of urea nitrogen in blood and is the end product of cellular metabolism (relative to the degree of renal impairment and rate of urea excreted by kidneys)
BUN elevated with:
- renal damage
- renal failure
- dehydration
- chronic or acute renal disease
- urinary obstruction
- GI bleed
- CHF
- shock
BUN decreased with:
- overhydration
- pregnancy
- liver failure
- secondary to smoking
- decrease protein intake
Types of Renal Cystic Disease
- simple renal cyst
- polycystic renal disease
- multicystic dysplastic kidney
- medullary sponge kidney
How often do simple renal cysts occur?
common, 50% of adults over 50 years
Where may simple renal cysts be found?
anywhere in the kidney
When are simple renal cysts clinically significant?
when they distort the adjacent calyces or produce hydronephrosis or pain
Son findings of simple renal cysts:
cystic properties
no septations
cyst may have a cyst or mass within it
Polycystic renal disease may present in two forms:
- autosomal-recessive form
- autosomal-dominant form
What is autosomal-recessive polycystic kidney disease (ARPKD)?
- fairly rare
- dilation of the renal collecting tubules which causes renal failure and in the later forms there is also liver involvement
Four forms of ARPKD?
-perinatal
-neonatal
-infantile
-juvenile
(the earler the symptoms manifest, the less the kidneys are functioning)
Son. findings of perinatal form of ARPKD?
- oligohydramnios
- enlarged echogenic kidneys
Son. findings of later forms of ARPKD?
- enlarged kidneys
- echogenic cortex and medulla
- lack of coritocmedullary differentiation
- may be macroscopic cysts (1-2mm) located in the medulla
- in children there may be also hepatic fibrosis and splenomegaly
What is Autosomal-dominant polycystic kidney disease (ADPKD)?
- common genetic disease in women and men
- bilateral disease characterized by multiple cysts located in the renal cortex and medulla
T/F: ADPKD cysts vary in size and may be asymmetrical?
T
When does ADPKD manifest?
- not until 4th or 5th decade of life
- by age 60, 50% will have end stage renal disease
Symptoms of ADPKD: 7
- pain
- hypertension
- palpable mass
- hematuria
- headache
- UTI
- renal insufficiency
Complications of ADPKD:
- infection
- hemorrhage
- stone formation
- rupture of cysts
- renal obstruction
Associated abnormalities of ADPKD:
- cysts in liver, spleen, pancreas, thyroid, ovary, testes, breast
- cerebral berry aneurysm (Circle of Willis) cerebral arteries
- increased incidence of renal cell carcinoma
- AAA
Statistics of Cerebral Berry Aneurysm
16% have it, 9% die from rupture
Sonographic findings of ADPKD in the fetus:
- moderately enlarged hyperchoic kidneys
- increased corticomedullary differentiation
- further screening necessary
- not compatible with life
Sonographic findings of ADPKD in adults:
- bilateral renal enlargement
- multiple cysts in both cortex and medulla
- advanced cases-normal parenchyma replaced with multiple cysts and kidneys lose shape
- cysts may grow large enough to obliterate renal sinus
- internal debris in cysts
- Walls of cysts may calcify, stones may form within cysts
- complicated cysts may result in spontaneous bleeding
What is multicystic dysplastic kidney?
non hereditary renal dysplasia that usually occurs unilaterally
What is the most common form of cystic disease in neonates?
multicystic dysplastic kidney
T/F: bilateral disease of multicystic dysplastic kidney is incompatible with life?
True
Complications of multicystic dysplastic kidney:
- hypertension
- hematuria
- infection
- flank pain
Son. finding of multicystic dysplastic kidney in neonates and children:
-kidneys appear enlarged
Son findings of multicystic dysplastic kidney in adults:
- kidneys small and calcified
- multiple cysts varying in size with no normal renal parenchyma
What is medullary sponge kidney?
- rare, non-hereditary benign renal disease
- congenital but may not be diagnosed until adulthood
What is medullary sponge kidney associated with?
dilated collecting tubules and cysts that form in the medulla
Son findings of of medullary sponge kidney:
- medulla is very echogenic
- may have associated calcium stones (nephrocalcinosis)
What is medullary nephrocalcinosis?
- calcium that forms in the medullary pyramids
- hyperechoic medullary pyramids with or without shadowing
What is medullary nephrocalcinosis associated with?
- medullary sponge
- hyperparathyroidism
- cushing syndrome
- adrenal gland tumors
- oral pharmocological doses of vitamin E, calcium, steroid use and malignant neoplasms
T/F: sonographic appearance of renal masses is specific
False, nonspecific
What is the first finding suggesting a mass may be present?
abnormal contour
List malignant renal masses:
- renal cell carcinoma
- transitional cell carcinoma
- Wilm’s tumor
- renal lymphoma