pancreas Flashcards
which enzyme parallels in elevation to amylase?
lipase
when will pancreatitis occur?
when pancreatic tissue becomes damaged as a result of increased secretion and blockage of ducts
4 causes of pancreatitis
alcoholism, trauma, peptic ulcer disease, biliary tract disease
what are the 5 B’s?
booze, blood, bile, bug, birth
what causes acute pancreatitis?
release of pancreatic enzymes into the surrounding tissue
what is the most common cause of pancreatitis in the US?
biliary tract disease
5 acute pancreatits symptoms
nausea, abdominal pain, fever, malaise, jaundice
5 clinical signs of acute pancreatitis
pleural effusion, pancreatic ascites, gallstones, lipase and amylase elevation
5 complications of acute pancreatitis
pseudocyst, phlegmon, abscess, hemorrhage, duodenal obstruction
sonographic findings of acute pancreatitis
swelling/enlargement, hypoechoic or anechoic, borders may be indistinct, compression of IVC
what is hemorrhagic pancreatitis?
rapid progression of acute pancreatitis with rupture of vessels and hemorrhage
what may cause focal areas of necrosis?
hemorrhagic pancreatitis
5 sonographic findings of hemorrhagic pancreatitis
enlarged pancreas, decreased echogenicity, depends on age of hemorrhage, well defined homogeneous mass, areas of necrosis
what is Grey Turner’s sign?
discoloration of glands due to necrosis of vessels resulting in hemorrhage
5 sonographic findings of chronic pancreatitis
increased echogenicity, decreased size, irregular borders, calcifications, dilated pancreatic duct
what causes a pseudocyst to develop?
enzymes that escape and break down tissue somewhere in the abdomen
what is the most common primary neoplasm of the pancreas?
adenocarcinoma
T or F? adenocarcinoma is the 4th most common cause of cancer related deaths
true
most common site for adenocarcinoma
pancreatic head
3 symptoms of adenocarcinoma
unexplained weight loss, palpable gallbladder, epigastric pain
how does cystadenoma appear and what may it be confused with?
thick walls, septa, cystic appearance
may be confused with pseudocyst
what is the malignant counterpart to cystadenomas?
cystadenocarcinoma
2 types of islet cell tumors
functioning–do produce hormones
nonfunctioning–do not produce hormones
how does the most common islet cell tumor appear?
B-cell tumor appears as numerous small lesions in body and tail
What are acinar cells?
the cells of the pancreas that carry out the exocrine function and therefore produce amylase, lipase, and sodium bicarbonate
What is acute pancreatitis?
inflammation of the pancreas secondary to the leakage of the pancreatic enzymes from the acinar cells into the parenchyma of the organ
What is the ampulla of Vater?
the merging point of the pancreatic duct and CBD just before the sphincter of Oddi, AKA hepatopancreatic ampulla
What is chronic pancreatitis?
the recurring destruction of the pancreatic tissue that results in atrophy, fibrosis, scarring, and the development of calcification within the gland
What is chyme?
partially digested food
Double-duct sign
co-existing enlargement of the cbd and pancreatic duct
What is duct of Santorini?
the accessory duct of the pancreas
What is the duct of Wirsung?
the main pancreatic duct
What is gastrinoma?
an islet cell tumor found within the pancreas