Upper Motor Neurones and Control of Movement Flashcards
describe the system which allows smooth walking action without input from upper motor neurones or motor cortex
2 adjacent excitatory pacemaker interneurons
- 1 involved in extension, 1 flexion
pacemaker interneurone excites efferent nerve to flexor muscle but also excited another inhibitory neurone which inhibits other pacemaker interneurone involved with extension, therefore flexion is excited and extension is inhibited
after a brief time delay, the inhibited pacemaker interneurone involved with extension then fires an AP which excites an inhibitory interneurone which inhibits the pacemaker interneurone involved with flexion, therefore extension is excited and flexion is inhibited
this cycle continues to allow smooth walking
there are 3 levels of hierarchy of motor control, what is the highest level?
highest level is involved with strategy of movement
structures involved = neocrotical association areas and basal ganglia
middle level of motor control?
tactical (how you will perform the plan made by higher level - what sequence of muscle contractions etc)
structures = motor cortex and cerebellum
(tactics must be stored in memory for a time)
low level of motor control?
involved in execution (activation of motor pools and interneuron pools that command the movement and make essential postural adjustments - to prevent falling while performing movement etc)
structures = brain stem and spinal cord
descending spinal tracts arise from where?
cerebral cortex (area concerned with motor comman - precentral gyrus - brodmann areas 6 and 4)
descending spinal tracts are concerned with what?
control of movement muscle tone spinal reflexes spinal autonomic functions modulation of sensory transmission to higher centres
2 divisions of descending pathways?
lateral pathways - lateral corticospinal tract - rubrospinal tract ventromedial pathways - pontine reticulospinal tract - meduallry reticulospinal tract - lateral vestibulospinal tract - tectospinal tract - ventral corticospinal tract
features and functions of lateral descending pathways?
under control from the cerebral cortex
important for voluntary movement of distal muscles (particularly discrete, skilled movements - e.g fractioned movement of arms - hands - fingers)
damage to what pathways can cause the loss of fractionated movement?
lateral pathways
- couldn’t move fingers and other joints independently, everything would move as one when trying to perform a task
functions of ventromedial pathways?
not under direct control of motor cortex
under control from nuclei in the brainstem
important for control of posture and locomotion (not so much involved in in fine, skilled or fractioned movement)
what is the major lateral pathway and describe its path?
corticospinal tract
cell bodies in motor cortex (BAs 4 and 6) and somatosensory areas of parietal cortex
axons course to the base of the medulla forming a tract (medullary pyramid)
85% of fibres cross here at the decussation of pyramids to form the lateral corticospinal tract (most important)
other 15% stay ipsilateral and form the ventral corticospinal tract and decussate more caudally
where do axons of the corticospinal tract terminate?
dorsolateral region of the ventral horn of the spinal cord
- area of LMNs and interneurons controlling distal muscles (particularly flexors)
describe the more minor lateral pathway
rubrospinal tract
cell bodies located in red nucleus (receives input from motor cortex and cerebellum)
axons decussate at the ventral tegmental decussation and descend the spinal cord ventrolateral to the lateral corticospinal tract, terminating in the ventral horn
functions of rubrospinal tract?
exerts control over limb flexors by exciting LMNs of these muscles
lesions of the lateral pathways is associated with what symptoms?
loss of fractionated movement
slowing and impairment of accuracy of voluntary movements
little effect on normal posture (sitting, standing etc)