Passmedicine Mix Flashcards

1
Q

upper and lower spinal levels of spinal cord?

A

begins at level of medulla oblongata

terminates at L1/L2

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2
Q

what anchors the spinal cord to the first coccygeal vertebra?

A

filum terminale

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3
Q

what divides the spinal cord into two hemispheres?

A

dorsal median sulcus

ventral median fissure

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4
Q

grey/white matter in spinal cord?

A

grey matter on the outside

white matter in the middle, continuous with the ventricular system in brain

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5
Q

how is the grey matter in the spinal chord organised?

A

cytoarchitecturally into laminae of rexed

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6
Q

features of temporal lobe seizure?

A
epigastric rising sensation
hallucinations (olfactory, gustatory, auditory)
automatisms (lip smacking, grabbing
,plucking)
de ja vu/dysphasia
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7
Q

features of frontal lobe seizure?

A
mainly motor
head/leg movements
posturing
post-ictal weakness
jacksonian march
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8
Q

features of parietal lobe seizure?

A

mainly sensory

paraesthesia

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9
Q

features of occipital lobe seizure?

A

mainly visual
floaters
flashing lights etc

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10
Q

what does the telencephalon become?

A

cerebral cortex
lateral ventricles
basal ganglia

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11
Q

what does the deincephalon become?

A

thalamus
hypothalamus
optic nerve
3rd ventricle

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12
Q

what does the mesencephalon become?

A

midbrain

cerebral aqueduct

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13
Q

what does the metencephalon become?

A

pons
cerebellum
superior part of 4th ventricle

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14
Q

what does the myelencephalon become?

A

medulla

inferior part of 4th ventricle

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15
Q

does wernicke’s encephalopathy cause cerebellar syndrome?

A

no
alcohol causes it but not wernickes
- wernickes is a thiamine deficiency

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16
Q

features of cerebellar syndrome?

A

DANISH

  • dysdiadokinesia
  • ataxia
  • nystagmus
  • intention tremor
  • slurred staccato speech
  • hypotonia
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17
Q

what causes chorea?

A

damage to basal ganglia (especially caudate nucleus)

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18
Q

what passes through the optic canal?

A

optic nerve

ophthalmic artery

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19
Q

what passes through the superior orbital fissure?

A
superior and inferior ophthalmic vein
CN III
CN IV
CN V1
CN VI
20
Q

what passes through foramen rotundum?

A

CN V2

21
Q

what passes through foramen ovale?

A

CN V3

22
Q

what passes through the jugular foramen?

A

internal jugular vein
CN IX
CN X
CN XI

23
Q

effects of anterior cerebral artery stroke?

A

contralateral hemiparesis and sensory loss

lower limbs more than upper limbs

24
Q

effects of middle cerebral artery stroke?

A

contralateral hemiparesis and sensory loss
upper limbs more than lower limbs
contralateral homonymous hemianopia
aphasia

25
Q

effects of a posterior cerebral artery stroke?

A

contralateral homonymous hemianopia with macular sparing

visual agnosia

26
Q

what is webers syndrome?

A

stroke of branches of posterior cerebral arteries which supply midbrain
causes ipsilateral CN III palsy and contralateral weakness of upper and lower extremity

27
Q

what is lateral medullary syndrome?

A

stroke of posterior inferior cerebellar artery
causes ipsilateral facial pain and temp loss and contralateral limb/torso pain and temp loss
ataxia and nystagmus

28
Q

what is lateral pontine syndrome?

A

stroke of anterior inferior cerebellar artery

causes symptoms similar to lateral medullary syndrome but with ipsilateral facial paralysis and deafness

29
Q

how does a lacunar stroke present?

A

either isolated hemiparesis, hemisensory loss of hemiparesis with limb ataxia
strong association with hypertension
common sites = basal ganglia, thalamus and internal capsule

30
Q

at what level does the spinal cord terminate?

A

around L1

31
Q

describe the function of A gamma fibres?

A

transmit fast pain (myelinated)

mainly mechanical pain

32
Q

function of C fibres?

A

transmit slow pain

mechanical and thermal pain

33
Q

which gene is the most likely cause of early onset alzheimers disease in downs syndrome patients?

A

amyloid precursor protein

located on chromosome 21

34
Q

lumbar puncture is performed at which vertebral level?

A

L3/L4

35
Q

function of A delta fibres?

A

temp and sharp pain

36
Q

function of A alpha fibres?

A

motor function - skeletal muscle

37
Q

function of A gamma fibres?

A

proprioception

38
Q

function of B fibres?

A

autonomic acitivty

39
Q

function of C fibres?

A

slow, dull, diffuse, poorly localised pain

thermal, mechanical and chemical pain

40
Q

features of a parietal lobe lesion?

A
sensory inattention
apraxia
gerstmann's syndrome
inferior homonymous quadrantanopia 
astereognosis
41
Q

what is gerstmann’s syndrome?

A

Inability to write (dysgraphia or agraphia)
the loss of the ability to do mathematics (acalculia)
the inability to identify one’s own or another’s fingers (finger agnosia)
inability to make the distinction between left and right

42
Q

features of occipital lobe lesion?

A

homonymous hemianopia with macular sparing
cortical blindness
visual agnosia

43
Q

features of temporal lobe lesion?

A

wernicke’s aphasia (cant comprehend speech)
superior quadrantanopia
auditory agnosia
prosopagnosia (cant recognise faces)

44
Q

features of frontal lobe lesion?

A
brocas aphasia (cant produce speech)
disinhibition
perserveration
anosmia
inability to generate a list
45
Q

features of cerebellum lesion?

A
midline = gait and trunk ataxia
hemispheres = nystagmus, dysdiadokinesia, intention tremor, past pointing