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GI--Wk 2 > Upper GI Micro > Flashcards

Upper GI Micro Flashcards

1
Q

Major bacteria causing caries

A

S. mutans

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2
Q

S. mutans virulence factors

A

AgI/II: adhesion-like surface-associated proteins

GTFs: extracellular glucosyltransferases

⇒ glucans from sucrose ⇒ glycocalyx formation for biofilm formation

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3
Q

Keystone pathogens

A

red group

important in remodelling flora

Porphyromonas gingivalis

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4
Q

Aggregatibacter actinomycetemcomitans

A

important in severe disease

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5
Q

Flouride effects

A

remineralization in low pH

inhibit bacterial glycolysis + pH maintenance enzymes

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6
Q

Sugarfree gum

A

increases salivary flow

creates more buffer

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7
Q

S. mutans

classification

A

Gram +

catalase -

facultative anaerobe

alpha-hemolytic

optichin-resistant

S. mutans

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8
Q

P. gingivalis

classification

A

Gram -

bacillus

anaerobic

asaccharolytic

black-pigmented colonies on blood agar plates

bacitracin-resistant

P. gingivalis

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9
Q

Gingivitis and peridontal disease due to

A

inflammation of bacterial colonization

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10
Q

DM and gingivitis inflammation

A

DM → increases inflammation

inflammation → poorer glycemic control

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11
Q

S. mitis

S. sanguinis

A

neutral bacteria

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12
Q

Ludwig’s angina

organisms

A

alpha-hemolytic strep

rash on chest

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13
Q

Esophageal candiditis

A

dangerous

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14
Q

Important enzyme in H. pylori

A

urease

makes NH3

makes more basic

chemotaxis to basic areas

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15
Q

H. pylori

virulence factors

A

VacA: pore forming cytotoxin, leakage of Ca2+ from epithelial cells

CagA: type 4 secretion system, highly proinflammatory

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16
Q

Dx of H. pylori

endoscopy

breath test

stool test

blood test

A

Dx of H. pylori

endoscopy: gold standard

breath test: radioactive CO2 from urease

stool test: active infection, direct antigen

blood test: only exposure

17
Q

Gastric carcionoma increased risk from

A

increased acid

GI--Wk 2 (11 decks)

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