Gastric Motility

Question 1

How to fill stomach

Answer 1

relaxation of muscles when food enters stomach

NT: VIP, NO

stretch receptors: dorsal vagal complex

ACh → relaxation

Question 2

Gastroileal reflex

Answer 2

ileocecal valve opens

small → large bowel movement

Question 3

Gastrocolic reflex

Answer 3

induces need to deficate after meal

Question 4

Mechanical movements in stomach

Answer 4

emulsification of fats

→ increase surface area

reducing solid side

Question 5

Absorption in stomach

Answer 5

lipid soluble substances

ASA

EtOH

**high levels of ASA and EtOH absorption associated with gastritis

Question 6

Food size into sm intestine

Answer 6

< 2 mm

retrograde movements to break up larger pieces

Question 7

Housekeeping gastric hormone

Answer 7

motilin

Question 8

Motilin actions

Answer 8

Occur during fasting:

quiescence period

irregular contractions

intense contractions

Question 9

Inhibitors of gastric emptying

Answer 9

acid in intestine

→ secretin and somatostatin

→ fat in duodenum via CCK

Question 10

Pyloric stenosis

Answer 10

congenital

Tx: surgical myotomy

Question 11

Gastroparesis causes

Answer 11

neuropathy of vagus and enteric nerves

DM, cancer Tx, drugs

Question 12

Dumping syndrome

Answer 12

rapid entry of gastric contests into duodenum

osmotic movements into lumen

hypovolemia and diarrhea

Question 13

Tears due to emesis

Answer 13

Mallory-Weiss tear

self-limiting hematemesis