Upper GI Ch 40 Flashcards
HCI = Hydrochloric acid is a substance that
<p>aid in the initial digestive process</p>
Problems of the upper GI occurs when
<p>Tissue damage and Ulcers</p>
Drugs that neutralize HCL and protect the mucosal singing are called
<p>Ant-acids </p>
Drugs that reduce the production of HCL include
<p>H2 Antagonist , Proton Pump Inhibitors and Misc. acide reducing agents. </p>
Proton pump inhibitors are particularly important in the treatment of
<p>H. Pylori with active duodenal ulcers</p>
GI stimulants facilitate
Emptying of the stomach contents into the Small Intestine
GI stimulants are used to treat both
<p>Ulcer Treatments and Antiemetics </p>
Action of ant-acids
- Neutralized/Reduce acid of the stomach and duodenal activity. 2.Acids are reduced by commingling HCL and increasing the PH of stomach acid
Do Ant-Acids coat the stomach
NO
Examples of Antacids
Aluminum, magaldrate and magnesium
What would I used to treat hyperacidity
Ant-acids
Hyperacidity is caused by
Heart burn Acid indigestion Sour Stomach GERD Peptic Ulcer
Aluminum Cabonate may be used in treating
Non-Antacid action
Hyperphosphatemia (Chronic Renal Failure)
Calcium may be used to treat (Non-Ant-acid action)
Calcium deficiencies in menopausal osteoporosis
Magnesium may be used to treat (Non Antiacid action)
Treating deficiencies or depletions from malnutrition, restricted diet or alcoholism .
What kind of adverse effect does magnesium and sodium containing antacids have
Laxative/Diarrhea
What kind of adverse effect does calcium havce
Constipations
Antacids are contraditcted in patients with
Patients with severe abdominal pain and during lactation
Sodium containing antacids are contradicted in patients with
Cardiovascular problems (Hypertension Heart Failure) Patients on Low Sodium Diets
If I have a patients on a low sodium diet what kind of antacid would I NOT give them
Sodium containing antacids
Calcium containing antaicds are contradicred in patients with
Renal Calculi and HyperCalemia
I have a patient with renal calculi what kind of Antacid would I not give her
Calcium containing antacid
Aluminum Cabonate are used cautiously in patients with
Non-Antacid action
Upper GI bleeding and Gastric outlet obstruction
Magneisum and Aluminium are used cautiously in patients with
Decreased Kidney function
Calcium containing are used cautiously in paitnes with
respritory insuffiency, renal impariment or cardiac disease
Drugs that reduce the production of HCL include
Histamine H2, Proton Pump Inhibitors, Pepsin inhibitors, prostaglandins and cholinergic blockers
Histamine H2 antagonist inhibit
the action of histmaine at the H2 recpetor calls of the stomach
Inhhibiting the action of histamine at the H2 receptor does what?
Reduced the secretaion of gastric acid
When ulcers are present in the stomach these are used to allow the ulcerated areas to heal
Histamine H2 Antagonist
Examples of H2 Antagonists
Cimetidine, famotidine and ranitidine
Uses of Histamine H2 Antagonists
- Stress-related uclers 2. Acute upper GI bleeding 3. Heart burn 4. Acid Indegestion 5. Sour Stomach 6. GERD 7. Gastric Duodental Ulcer 8. Gastric Hypersecretory conditions
Adverse reactions to Histamine H2 antagonist
Dizziness, somnolence, headache, confusion, hallucinations, diarrhea and reversible impotence
Histmine is contrdicted in patients with
Heptic impairment, severly ill, older or debilitated patients.
Cimetidine is used cautiusly in patients with
Diabetes
Proton pump inhibitors do what?
Supress gastric acid secreation
Examples of Proton Pump Inhibitor examples
Esomeprazole and omeprazole
Proton Pumo Inhibitors are used to treat
Gastric Duodenal Ulcers (H.Pylori) GERD and erosive esophagitis, pathologic hypersecretory conditions prevention of bleeding in high risk patients using anti platelet durgs
Proton Pumo Inhibitor adverse reactions
Headache, Nausea, Diarrhea and Abdominal pain
Prolonged treatment with Proton Pump Inhibitor may cause a decrease in the bodies ability to absorb
Vitamin B12 resulting in Anemia
Proton Pump Inhibitors are used cautiously in these patients
Older Adults with heptaic impairment