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Pharmacology > Upper GI Ch 40 > Flashcards

Upper GI Ch 40 Flashcards

1
Q

HCI = Hydrochloric acid is a substance that

A

<p>aid in the initial digestive process</p>

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2
Q

Problems of the upper GI occurs when

A

<p>Tissue damage and Ulcers</p>

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3
Q

Drugs that neutralize HCL and protect the mucosal singing are called

A

<p>Ant-acids </p>

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4
Q

Drugs that reduce the production of HCL include

A

<p>H2 Antagonist , Proton Pump Inhibitors and Misc. acide reducing agents. </p>

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5
Q

Proton pump inhibitors are particularly important in the treatment of

A

<p>H. Pylori with active duodenal ulcers</p>

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6
Q

GI stimulants facilitate

A

Emptying of the stomach contents into the Small Intestine

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7
Q

GI stimulants are used to treat both

A

<p>Ulcer Treatments and Antiemetics </p>

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8
Q

Action of ant-acids

A
  1. Neutralized/Reduce acid of the stomach and duodenal activity. 2.Acids are reduced by commingling HCL and increasing the PH of stomach acid
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9
Q

Do Ant-Acids coat the stomach

A

NO

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10
Q

Examples of Antacids

A

Aluminum, magaldrate and magnesium

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11
Q

What would I used to treat hyperacidity

A

Ant-acids

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12
Q

Hyperacidity is caused by

A 
Heart burn 
Acid indigestion 
Sour Stomach 
GERD
Peptic Ulcer
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13
Q

Aluminum Cabonate may be used in treating

Non-Antacid action

A

Hyperphosphatemia (Chronic Renal Failure)

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14
Q

Calcium may be used to treat (Non-Ant-acid action)

A

Calcium deficiencies in menopausal osteoporosis

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15
Q

Magnesium may be used to treat (Non Antiacid action)

A

Treating deficiencies or depletions from malnutrition, restricted diet or alcoholism .

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16
Q

What kind of adverse effect does magnesium and sodium containing antacids have

A

Laxative/Diarrhea

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17
Q

What kind of adverse effect does calcium havce

A

Constipations

18
Q

Antacids are contraditcted in patients with

A

Patients with severe abdominal pain and during lactation

19
Q

Sodium containing antacids are contradicted in patients with

A

Cardiovascular problems (Hypertension Heart Failure) Patients on Low Sodium Diets

20
Q

If I have a patients on a low sodium diet what kind of antacid would I NOT give them

A

Sodium containing antacids

21
Q

Calcium containing antaicds are contradicred in patients with

A

Renal Calculi and HyperCalemia

22
Q

I have a patient with renal calculi what kind of Antacid would I not give her

A

Calcium containing antacid

23
Q

Aluminum Cabonate are used cautiously in patients with

Non-Antacid action

A

Upper GI bleeding and Gastric outlet obstruction

24
Q

Magneisum and Aluminium are used cautiously in patients with

A

Decreased Kidney function

25
Q

Calcium containing are used cautiously in paitnes with

A

respritory insuffiency, renal impariment or cardiac disease

26
Q

Drugs that reduce the production of HCL include

A

Histamine H2, Proton Pump Inhibitors, Pepsin inhibitors, prostaglandins and cholinergic blockers

27
Q

Histamine H2 antagonist inhibit

A

the action of histmaine at the H2 recpetor calls of the stomach

28
Q

Inhhibiting the action of histamine at the H2 receptor does what?

A

Reduced the secretaion of gastric acid

29
Q

When ulcers are present in the stomach these are used to allow the ulcerated areas to heal

A

Histamine H2 Antagonist

30
Q

Examples of H2 Antagonists

A

Cimetidine, famotidine and ranitidine

31
Q

Uses of Histamine H2 Antagonists

A
  1. Stress-related uclers 2. Acute upper GI bleeding 3. Heart burn 4. Acid Indegestion 5. Sour Stomach 6. GERD 7. Gastric Duodental Ulcer 8. Gastric Hypersecretory conditions
32
Q

Adverse reactions to Histamine H2 antagonist

A

Dizziness, somnolence, headache, confusion, hallucinations, diarrhea and reversible impotence

33
Q

Histmine is contrdicted in patients with

A

Heptic impairment, severly ill, older or debilitated patients.

34
Q

Cimetidine is used cautiusly in patients with

A

Diabetes

35
Q

Proton pump inhibitors do what?

A

Supress gastric acid secreation

36
Q

Examples of Proton Pump Inhibitor examples

A

Esomeprazole and omeprazole

37
Q

Proton Pumo Inhibitors are used to treat

A

Gastric Duodenal Ulcers (H.Pylori) GERD and erosive esophagitis, pathologic hypersecretory conditions prevention of bleeding in high risk patients using anti platelet durgs

38
Q

Proton Pumo Inhibitor adverse reactions

A

Headache, Nausea, Diarrhea and Abdominal pain

39
Q

Prolonged treatment with Proton Pump Inhibitor may cause a decrease in the bodies ability to absorb

A

Vitamin B12 resulting in Anemia

40
Q

Proton Pump Inhibitors are used cautiously in these patients

A

Older Adults with heptaic impairment

Pharmacology (10 decks)

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