EXAM 3 pain management nonopiod Flashcards

1
Q

Drugs used to relieve pain without possibility of causing physical dependency

A

Nonopiod Analgesics

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2
Q

analgesic

A

pain relieving

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3
Q

antipyretic

A

decrease body temperature

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4
Q

anti-inflammatory

A

decrease inflammation

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5
Q

nonopiod analgesics:

A
  • salicylates
  • non salicylate
  • non steroidal anti-inflammatory drugs (NSAIDS)
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6
Q

examples of salicylates

A
  • aspirin (acetylsalicylic acid or ASA)

- Bayer, Ecotrin, Anacin

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7
Q

aspirin woman became the new anti-power:

A
  • Anti-inflammatory
  • Anti-pain
  • Anti-pyretic
  • Anti-platelet aggregation
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8
Q

when taking aspirin, watch for

A
  • bleeding tendencies
  • tinnitus
  • stomach pain
  • thrombocytopenia
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9
Q

salicylates action

A

-Analgesic and anti-inflammatory action due to inhibition of prostaglandins
(Lower Temp by dilating peripheral blood vessels = cools body)

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10
Q

ASA as anticoagulant

A

–Inhibits aggregation of platelets
(Important for MI and stroke patients)
–Prolong bleeding time =risk for bleeding

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11
Q

Salicylates allergic reactions

A

hives, bronchospasm and anaphylaxis

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12
Q

Salicylism

A

toxicity from repeated admin of large doses (reversible with dose reduction)

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13
Q

S&S of salicylism:

A
  • Tinnitus, Impaired Hearing
  • Mental confusion, lassitude
  • Sweating, tachycardia
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14
Q

salicylates contraindications:

A
  • known hypersensitivity to Salicylates or NSAIDS

- bleeding disorders or tendencies

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15
Q

Children and Teens with flu or chickenpox should not salicylate take due to association with -

A
Reyes Syndrome (life threatening)
-> Vomiting, lethargy, progressing to coma
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16
Q

antacids may ___ the effect of Salicylates

A

decrease

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17
Q

Aspirin may ____ risk of bleeding during _____ administration

A

increase; heparin

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18
Q

Admin with NSAIDS may ____ NSAID blood levels

A

increase

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19
Q

NonSalicylates

A

-Acetaminophen (Tylenol)

choice for treating children w fever/flulike symptoms

20
Q

Actions of NonSalicylates

A
  • Analgesic
  • Antipyretic
  • No Anti-Inflammatory actions
21
Q

Adverse reactions of NonSalicylates

A
  • few when taken as directed
  • urticaria
  • pancytopenia
  • JAUNDICE, hepatotoxicity, hepatic failure
22
Q

Tylenol overdose:

acute

23
Q

Tylenol overdose: fatal

24
Q

increase risk of tylenol overdose with-

A

chronic alcoholics

25
tylenol overdose
liver cells die, cannot detoxify drug
26
s&s of tylenol toxicity
- N/V - Jaundice, Liver tenderness - Hypotension - Confusion - Acute Hepatic and Renal Failure
27
Caution w tylenol
- Chronic Alcoholics - Avoid concurrent use with Salicylates or NSAIDS - Cautious use in pregnancy - Cautious use in older adults
28
NSAIDS
Inhibit prostaglandin synthesis by inhibiting an enzyme that triggers pain and inflammation.
29
NSAIDS does not belong to
steroid group of drugs
30
actions of NSAIDS
- Anti-inflammatory - Antipyretic - Analgesic
31
EXAMPLES OF NSAIDS:
- Ibuprofen (Motrin, Advil) - Indocin - Toradol - Naproxen (Naprosyn) - Feldene - Celebrex, Vioxx
32
USES of NSAIDS
- mild-mod pain - RA - Osteoarthritis - Dysmenorrhea (painful periods)
33
NSAID adverse reactions GI tract
- A/N/V/D/C - Epigastric pain, indigestion - Abdominal distress, bloating - Intestinal ulceration - jaundice
34
NSAID adverse reactions CNS
- Dizziness, vertigo, lightheadedness - Headache, anxiety - Insomnia, depression, confusion - Psychic disturbances
35
NSAID adverse reactions cardiovascular
- CHF - Decrease or in crease in BP - Arrhythmias
36
NSAID adverse reactions renal
- Hematuria, polyuria, dysuria, oliguria - Cystitis - Elevated BUN - Acute renal failure
37
NSAID adverse reactions special senses
- Visual disturbances - Blurred vision, diplopia, photophobia - Tinnitus, taste changes,
38
NSAID adverse reactions hematologic
- Luekopenia - Pancytopenia - Thrombocytopenia - Neutropenia
39
NSAID adverse reactions skin
- Rash, irritation - Erythema - Exfoliative dermatitis - Ecchymosis
40
NSAID adverse reactions metabolic/endocrine
- Weight increase or decrease - Hyper/hypoglycemia - Flushing, sweating - Menstrual disorders, vag bleeding
41
Contraindication to NSAIDS
- known hypersensitivity - allergies to ASA - 3RD trimester of pregnancy and lactation
42
precautions of NSAIDS
- Bleeding disorders - Renal disease - CV disease - Hepatic disease - Elderly (increased risk of ulcer formation in patients over 65)
43
-Give with food, milk or full glass of water To prevent gastric upset -Avoid salicylates 1 week before major or minor surgery (To prevent post-op bleeding) -Avoid salicylates after surgery (use Tylenol or NSAID) until healing complete
salicylates
44
- With full glass of water - With meals or empty stomach - Acetylcysteine (Mucomyst) is an antidote for acetaminophen (Tylenol) overdose
NonSalicylates
45
- With food, milk or antacids | - Several weeks may be necessary on drug to receive full therapeutic response
NSAIDS