Exam 3 Antibacterial Drugs Interfere with DNA and RNA synthesis

Question 1

Fluorquinolones interfere with

Answer 1

a DNA enzyme needed for synthesis of DNA

Question 2

Misc Anti-Infectives inhibit

Answer 2

RNA/DNA synthesis

Inhibit cell wall synthesis

Question 3

Examples of Fluoroquinolones

Answer 3

ciprofloxacin
levofloxacin
ofloxacin

Question 4

Examples of Misc Anti-Infectives

Answer 4

metronidazole (Flagyl)

rifaximin (Xifaxan

Question 5

Uses Misc Anti-Infectives

Answer 5

VRE, Serious infections such as C. diff, endocarditis, septicemia

Question 6

Uses Fluoroquinolones

Answer 6

gram-positive and negative bacteria

Question 7

Fluoroquinolones are also used on

Answer 7

Lower respiratory infections, bone/joint infections, UTI’s, skin infections, and STI’s

Question 8

Adverse Reactions Fluoroquinolones

Answer 8

• Nausea
• Diarrhea
• Headache
• Abdominal pain or discomfort
• Dizziness
• Photosensitivity

Question 9

Adverse Reactions Misc Anti-Infectives

Answer 9

Nausea
Vomiting
Rash
Insomia
Nephrotoxicity
Ototoxicity
Chills
Fever

Question 10

Nursing Process Anti Bacterial Medications

Answer 10

Identify signs/symptoms of the infection
Evaluate IM sites for soreness
Evaluate IV sites for inflammation or extravasation
Evaluate for superinfections
Evaluate for s/s of serious reactions
Oto-nephro-neurotoxicty

Question 11

Monitor Blood Levels Peak =

Answer 11

time of maximum effect, commonly measured immediately after the drug has been infused

Question 12

Monitor Blood Levels Trough =

Answer 12

level before the next dose (30 minutes before dose)

Question 13

Monitor CBC =

Answer 13

especially WBC and differential to eval effectiveness (WBC will decrease to normal range)