Untitled spreadsheet - uveitis Flashcards
what is heerfordt’s yndrome
AAU, facial palsy, parotid enlargement
which form of IB does iritis commonly occur
10% in UC, 5% in Crohn’s
MOA of mtx
folate analog inhibits dihydrofolate rucatase
safest drug to treta toxo in pregnancy
clinda
urine calcium or serum calcium elevated in sarcoid
urine calcium
organisms for diffuse inilateral dusn
bayliascaris
HLA associated with POHS
B7
Hep B surface antigen is positive in what percent of patients with classic PAN
10-50%
HZO kind of iris atrophy
sectoral
HLA associated with serpiginous
B7
demographic of serpingenous
young healthy adults with no systemic findings. Vitirits in 30%.
which anesthetics increase IOP?
ketamine
most anesthsia’s effect on IOP
kiwers
importantce of echothiophate when planning surgery
increaes outflow of aqueous humor, decreases efficacy of pseudocholinease, therfoe affects metaboism of succinyl choline.
toxicity of chloramphenicol
aplastic anemia, optic atrophy, gray syndrome
MOA of rifampin
inhibityis bacterial RNA synethesis.
strength of steroid
dex, methyl, pred, hydro, cortisone
how do acetate and sodium phosphate differ
phosphate: water soluble, ocular absorption limited, acetate water insoluble
organisms associated with Reiter’s
chlyamydia, ureaplasm, yeresina, shigella, salmonella
pathology of Fuch’s heterochromic iridicyclitis
plasma cells in cb
wardenberg’s syndrome
iris heterchormia, telecanthus, whiteforelock, congenital deafness
hypersentivitiy of phacoanaphylactic endophthamitis
type III
intermediate uveitisi in MS
usually bilateral, band keratopathy
CME in VKH?
no
ARN
vitiritis, usually in posteiror pole
PORN
minimal inflammation, peripheral spots.
3 signs of rubella
hearing loss, salt and pepteper retinopathy, cataract or glacuoma.
4 findings of measles
pigmentary retinopathy, conjuncitivtis, retinal edema, vacularf attenuation, koplik’s spots
findings of SSPE
fatal measles, macular or perimacular chorioretinitis, bone specules, personality behavior changes.
association with pneumocystis
associated with inhaled pentamidine
two worms associated with DUSN
dogworm: ancylostoma canium, racoon nematomde : Bayliscaris procynois
rx for onchocerciasis:
ivermectih, surmain, DEC
malabosportion, uveitis, vasculitis
whipple’s disease
what causes whipple’s disease
G+ bacillus, actinomycetes, PAS positive macrophages
what kind of organisms is P. acnes
anaerboci G_ rod
young F=M, bilateral, flu
APMPPE
findings of APMPPE
multiple plaques, early hypo with late hyper. Associated with cerebral vasculitis
F>M, unilateral, small soft spots, shimmering photopsias
MEWDs
rx for apmppe
none
FA for MEWDS
early hyper wreath configuration, ERG shows reduced a wave
rx for birdshot
steroids +IMT
20-50, young myopic women, multiple spots, fill early stain latea
MCP
healthy myopic woman with acute scotomas, photopsiasm no vitirits, FA early hyper late staining
PIC
what is lofgren’s syndrome
hilar lymphadenophaty, erythema nodusm, AAU, arthalgia
Mikulicz’s syndrome
lacrimal and parotid swelling due to saccoid, tb, lymphoma/leukemia
what is heerfordt’s sndrome
fever, partodi gland enlagement AU, facial nerve palsy.
HLA association for VKH
DR4
4 stages of VKH
prodormal, syndrome, chronic, recurrent
panuveitis that spares choriocapillaris
SO
IOL for JRA?
No
most common JRA with uveitis
RF-, ANA+ pauciarticular, 90% female
which one affects 90% males?
pauciarticular late onset, RF, ANA negtive, HLAB-27 +
what is characteristic of still’s disease
60% male, RF -, ANA-,
sex of polyarticular
85% girls, uveitis rare, 75% RF negative
what is the difference between pauciarticular type I and type II
type I: girls, 60% ANA positrive, type II 90% boys, 75% HLA-B27 positive.
ddx for posterior uveitis in kids
toxo, lyme, POHS, HSV,
which organism in toxo causes inflammation
tachyzoite
Which disorders associated with th1 response?
So, Vkh. Birdshot
What is the th1 pathway?
Il-8 tnf activated macrophage.
what are kyrieleis’ plaques
white spots along arterioles
cause of toxocariasis
2nd stage larval form of dog hookworm toxocara canis, through contaminated soil
What is th2 pathway?
Il-4. Il-(,10- eosinophils, atopic disease
trio of toxocara
endophthamisi, localized,g ranuloma, or peripheral granuloma, high eosinophils