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OKAPS Flashcards- Cornea

1
Q

What disease is associated with Cogan’s syndrome

A

PAN

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2
Q

IK and deafness

A

syphillis

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3
Q

Where are accessory lacrimal glands

A

Wolfring- tarsus, Krause- conjunctival fornices

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4
Q

Enlarged corneal nerves

A

KCN, refsums’s NF, PPMD, Fuch’s Reiss Bucklers

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5
Q

Findings in Terrien’s marginal degeneration

A

high ATR astigmatism in opposite angle of thinning

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6
Q

Findings of Ehlers Danose

A

KCN, blue sclera, high myopia

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7
Q

Which mucopolysaccharidoses are assocaitd with corneal clouding?

A

All but hunter’s and sanfilipinos

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8
Q

Causes of corneal verticillatea

A

amiodarone, antimalariesals, tamoxifen, fabry’s disease

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9
Q

cause of Fabry’s disease

A

deficiency of alpha galactosidase

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10
Q

Histopathology of Salzman’s

A

replacement of bowman’s with hyaline

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11
Q

PUK+positive HbsAg

A

PAN

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12
Q

Ocular features of PAN

A

PUK, necrotizing scleritis, secondary Sjorgen’s

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13
Q

Noninflammatory slowly progressive thinning of peripheral cornea begins superiorly has associated vascular pannus

A

Terrien’s

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14
Q

Systemic features of keratconus

A

Down’s, atopy, marfan’s ehlers danose, MVP

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15
Q

Which anti-Epstein Barr virus antibody does not peak during first 6-8 weeks?

A

EBNA

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16
Q

Corneal clouding in infants

A

S infectious Trauma - Ulcer-Metabolic Peter’s Dystrophy

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17
Q

HLA-DR3, tearing, small corneal epithelial lesions

A

Thygeson’s

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18
Q

Causes of IK

A

syphillis, herpes, TB, leprosy, rubeola, EBC, chlamaydia, onchocerca

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19
Q

systemic association with SLK

A

Thyroid

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20
Q

shiledl shaped anterior subcaspular or PSC opacaities

A

atopic

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21
Q

staining pattern of RGP lens overwear

A

3 and 9 o’clock

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22
Q

where does glucose for corneal epithelium come from

A

aqueous humor

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23
Q

which antiviral produces preauricular lymphadenopathy

A

idoxurine

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24
Q

hyperkeratotic lesions of palms, elbows,

A

tyrosinemia type II

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25
Q

very short person photophobic with polychromatic conjunctival and corneal crystrals

A

cystinosis

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26
Q

rx for cystinosis

A

cysteamine

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27
Q

difference between neonatal and adult inclusion conjuncitivitis

A

follicular response rare in kids

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28
Q

difference in papillae between atopic, vernal and GPC

A

atopic- papillae in inferior palpebral, VC, GPC in superior tarsus.

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29
Q

avg corneal diameter adult

A

12.5x11.5, vert by horizontal

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30
Q

acg corneal diameter kid

A

9.5x10.5

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31
Q

power of cornea

A

49 front, -6 back

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32
Q

Descemet’s membrane

A

fetal banded anterior, adult nonbanded, thickens with age

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33
Q

assocations with atopic conjunctivitis

A

KCN, PSC (Maltese cross), HSV keratitis

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34
Q

ddx chronic follicular conjuncitivitis

A

chlymadia, mediacmentosa, HSV, Lyme, parinaud’s, atopic

35
Q

Adenovirus with pharynconjunctival fever

A

3,4,5,7. 8,19,37 with epidemic

36
Q

unilateral follicular conjuncitivitis, penumonitis

A

Newcastle’s occurs in pouletry handlers

37
Q

HPV viruses associated with CIN

A

16, 18, actinic exposure

38
Q

rare variant of squamous cell with malignant goblet cells

A

Mucoepidermoid, stains with mucicarmine, alcian blue

39
Q

Seen in halifax, North carolina, bilateral dyskeratotic lesions

A

benign heriditary intraepithelial dyskeratotis AD

40
Q

lacrimal and parotid gland swelling and KCS due to sacroid, TB, lymphoma, leukemia

A

Mikulicz’s syndrome

41
Q

Cogan’s syndrome

A

IK with Menier’s like vestibular dysfunciton, 80% progress to deafness without steroids

42
Q

ddx of keratitis with vestibuloauditory symptoms

A

syphilis, PAN, Wegner’s sarcoid, SO, VKH, cerebellpontine angle tumor.

43
Q

bilateral, goldben brown deposits

A

spheroidgal degeneration

44
Q

corneal mucopolysaccharidoses with retinopathy only

A

Hunter’s, sanfilipo’s

45
Q

Mucopolysaccardigoses with no corneal clouding or retinopathy

46
Q

Mucopolysaccharidoses inheritance

A

AR except Hunter’s, most have corneal clouding, retinopathy, and optic atrophy

47
Q

Sphingolipidoses inheritance

A

AR except Fabry’s X linked, most affect retina except fabry’s

48
Q

alpha galactosidae deficiency

A

Fabry’s disease

49
Q

Findings of fabry’s disease

A

corneal verticillata, cataracts, vascular anomalities of heart kidney, brain

50
Q

ddx of corneal verticillata

A

amiodarone, chlooroquine, indomethjacin, pheothiazine

51
Q

HDL deficinecy, relapsing polyneuropathy, deep stromal opacities

A

Tangier’s disease (AR)

52
Q

diffuse clouding, denser in periphery

A

fish eye disease

53
Q

arcus

A

Hyperlipoporteinemia types 2,3,4

54
Q

findings of cystinosis

A

sal and pepper fundus, no visual symptoms, polyuria, retardation, cystine crystals in conj, cornea, iris, lens retina

55
Q

rx of cystinosis

A

cysteamine

56
Q

refractile branching linear opacities, triad of painfu hyperkertotic skin lesions, keratitis, and mental retaration

A

Tyrosinemia type II ®

57
Q

young kid with reccurrent HSV keratitis

A

tyrosinemia type II

58
Q

corneal melt only in cornea, spreads circumferentially

A

Mooren’s ulcer

59
Q

what hypersensitivity, and what associations with Mooren’s

A

type II, with hep C, crohn’s

60
Q

painless progressive bilateral stromal thinning starts superiorly

A

Terrien’s

61
Q

causes of PUK

A

RA, Wegner’s relapsing polychondrisis, PAN, SLE, slceralderma behcet’s

62
Q

organisms which can penetrate cornea

A

gonorrhea, cornebacterium, shigella, H aegyptis listeria

63
Q

HSV resides in what ganglion

64
Q

immune ring in cornea

A

type III hypersensitivity

65
Q

differences between HSV AND HZV dendritie

A

HZV- no terminal bulbs

66
Q

fungi

A

septate- fusarium aspergillus, cuvulaea, nonseptate- mucor

67
Q

dimorphic fungi

A

histo, blasto, cocci

68
Q

book answer for rx for aspergiillus

A

clotrimazole

69
Q

recurrence of acanthomeba after PK

70
Q

rx for microsporida keratitis

A

fumagillin

71
Q

antigens for eBV

A

EBNA, VCA-IgM last for life. Others peak at 6-12 weeks.

72
Q

KCN histology

A

breaks in bowman’s

73
Q

associations of eratoglobus

A

connective tissue disorderes, LCA,

74
Q

pathology of Map, dot fingerprint

A

epithelial redublication

75
Q

Anterior corneal dystrophies

A

map,dot, fingerprint, messman’s, gelatinous, resibuckler’s thiel behke

76
Q

AR corneal dystrophies

A

macular, gelatinous

77
Q

difference between reiss buckler’s thiel benhke

A

reiss- curly filaments on EM, thiel- saw toothed epithelium

78
Q

yellow crystals below bowman’s hyperolipidemia

A

central crystaline schnder’s

79
Q

dystrophy where vision not affected

A

fleck, tiny wreath like opacitiy

80
Q

nonprogresive, vision not affected, tiles in the floor

A

central cloudy of francois, similar to crocodile shagreen

81
Q

brown mclean syndrome

A

peripheral corneal decompensation in aphakicpatients central cornea clear

82
Q

MEN 1

A

pituitary, parathyroid and pancreas

83
Q

MEN 2

A

mdullary thrydoid, peho, parathyroid, can get GI neuromas

OKAPs (10 decks)

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