Okaps flashcards - glaucoma

1
Q

Name 2 RGC cells

A

M cells: large diameter axons, dim light. P cells: small diameter axons, color and fine detail

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2
Q

Blood flow to four layers of optic nerve

A

NFL: CRA, prelaminar: sort posterior, laminar: posteiror ciliary, retrolaminar: branches of meningeal and CRA

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3
Q

composition of vitreous

A

99% protein free, very high vit C, calcium is half of plasma, lactate in aquous is higher

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4
Q

where in the TM is resistance the greatest?

A

juxtracanalicular meshwork

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5
Q

cause of ACG in pt who underwent scleral buckle

A

anterior rotation of ciliary body

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6
Q

what drug when added to betaxol procduce and ocular hypotensive effect equivalent to timolol

A

dipivefrin

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7
Q

function of longitudinal and circular fibers

A

long: insert into scleral spur, affect outflow, circular: affect acomodation.

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8
Q

helmotz theory of accomodation

A

contraction of long pulls lens forward, shallowing AC. Contraction of circular relaes zonules, lens more spherical, more focusing power. Relaxation of circular fibers tightens zonules, streches lens, makes I tthinner

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9
Q

production of aqueous

A

by active secretion, Na/K pump and carbonic anhydrase

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10
Q

how to measure aquous humor

A

fluorophotometry, AC volume 250 ul, PC 60 ul

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11
Q

compositionof aquous

A

acidic 7.2, 15x more ascorbate, low protein, lower CA, phos, otherwise similar

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12
Q

outflow pathway

A

uveoscleral meshwork, corneal scleral, juxtacnalicular, schlemms collector channels, veins, SOV, cavernous inus

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13
Q

effect of cycloplegics on uvealscleral outflow

A

increases

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14
Q

ddx of blood in sclem’s cnal

A

elevated episcleral venous pressure, nevus of ota, NF, congenital ectropion uvae

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15
Q

IOP changes with

A

higer lying down than siting, lower after exercise.

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16
Q

extent of visual field

A

60 nasally, 75 omferopr; 100 temporally

17
Q

goldman test size

A

I-V each increment doubles diameter, quadroulds area

18
Q

goldman light filter

A

1-4 incrememnts to 5 db, a-e 1 db.

19
Q

chromosome of pigmentary glaucoma

A

15

20
Q

krunkenberg’s spindle

A

melanin phagocytized by corneal endothelium

21
Q

causes of elevated episcleral venous pressure

A

CCF, sturge weber, NF, orbital mass, TED

23
Q

plateau iris

A

deep central AC, shallow peripheral

24
Q

mechanism of malignant glaucoma

A

entire AC shallow, has PI

25
Q

RF for aqeuous misdirection

A

uveitis, angle closure, nanophthalmis, post op

26
Q

rx for malignant glaucoma

A

cycloplegia, pulls lens iris diaphragm posteriorly, aqueous suppressents.

27
Q

mechanism of MMC

A

intercaltes with DNA 100x more potent thant 5FU

28
Q

mechanism of 5FU

A

affects S phase,