Okaps flashcards - glaucoma

(27 cards)

1
Q

Name 2 RGC cells

A

M cells: large diameter axons, dim light. P cells: small diameter axons, color and fine detail

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2
Q

Blood flow to four layers of optic nerve

A

NFL: CRA, prelaminar: sort posterior, laminar: posteiror ciliary, retrolaminar: branches of meningeal and CRA

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3
Q

composition of vitreous

A

99% protein free, very high vit C, calcium is half of plasma, lactate in aquous is higher

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4
Q

where in the TM is resistance the greatest?

A

juxtracanalicular meshwork

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5
Q

cause of ACG in pt who underwent scleral buckle

A

anterior rotation of ciliary body

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6
Q

what drug when added to betaxol procduce and ocular hypotensive effect equivalent to timolol

A

dipivefrin

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7
Q

function of longitudinal and circular fibers

A

long: insert into scleral spur, affect outflow, circular: affect acomodation.

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8
Q

helmotz theory of accomodation

A

contraction of long pulls lens forward, shallowing AC. Contraction of circular relaes zonules, lens more spherical, more focusing power. Relaxation of circular fibers tightens zonules, streches lens, makes I tthinner

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9
Q

production of aqueous

A

by active secretion, Na/K pump and carbonic anhydrase

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10
Q

how to measure aquous humor

A

fluorophotometry, AC volume 250 ul, PC 60 ul

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11
Q

compositionof aquous

A

acidic 7.2, 15x more ascorbate, low protein, lower CA, phos, otherwise similar

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12
Q

outflow pathway

A

uveoscleral meshwork, corneal scleral, juxtacnalicular, schlemms collector channels, veins, SOV, cavernous inus

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13
Q

effect of cycloplegics on uvealscleral outflow

A

increases

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14
Q

ddx of blood in sclem’s cnal

A

elevated episcleral venous pressure, nevus of ota, NF, congenital ectropion uvae

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15
Q

IOP changes with

A

higer lying down than siting, lower after exercise.

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16
Q

extent of visual field

A

60 nasally, 75 omferopr; 100 temporally

17
Q

goldman test size

A

I-V each increment doubles diameter, quadroulds area

18
Q

goldman light filter

A

1-4 incrememnts to 5 db, a-e 1 db.

19
Q

chromosome of pigmentary glaucoma

20
Q

krunkenberg’s spindle

A

melanin phagocytized by corneal endothelium

21
Q

causes of elevated episcleral venous pressure

A

CCF, sturge weber, NF, orbital mass, TED

23
Q

plateau iris

A

deep central AC, shallow peripheral

24
Q

mechanism of malignant glaucoma

A

entire AC shallow, has PI

25
Q

RF for aqeuous misdirection

A

uveitis, angle closure, nanophthalmis, post op

26
rx for malignant glaucoma
cycloplegia, pulls lens iris diaphragm posteriorly, aqueous suppressents.
27
mechanism of MMC
intercaltes with DNA 100x more potent thant 5FU
28
mechanism of 5FU
affects S phase,