Unit 9-Neuro Flashcards

1
Q

What are types of primary headaches

A

migraine, tension-type headache, cluster headache

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2
Q

What are main causes of secondary headaches

A

head or neck trauma; cranial or cervical vascular disorder; substance or its withdrawal; infection, sinuses

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3
Q

What headache characteristics would warrant worry?

A

onset after 50 y/o, sudden onset, accelerated pattern, fever and stiff neck, neuro changes

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4
Q

What are symptoms of tension headache?

A

dull pain radiating bilaterally from forehead to occiput in band like fashion-radiates into neck and trapezius-NOT present on awakening, rarely debilitating

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5
Q

What are symptoms of migraine headache?

A

nausea, photophobia, more women than men

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6
Q

What are symptoms of cluster headaches?

A

more in men, hypothalmic disorder is possible, occurs at specific times in sleep-wake cycle. Unilateral, stabbing in one eye, 15-180 min, 1-8 times daily

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7
Q

What can cause chronic daily headaches?

A

treating more than 2 headaches per week

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8
Q

How long do you need to withhold pain meds to treat MOH?

A

1-2 weeks

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9
Q

Who needs prophylaxis for tension headaches?

A

those who have more than 2 TTHs per week

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10
Q

What is first line treatment for TTH?

A

ASA and APAP

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11
Q

What is second line treatment for TTH?

A

NSAIDS, caffeine containing meds

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12
Q

What is third line treatment for TTH?

A

butalbital compounds

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13
Q

Where are migraines thought to originate?

A

trigeminovascular system of cerebrum

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14
Q

What is first line treatment for Migraine?

A

NSAIDS

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15
Q

What is 2nd line treatment for Migraine?

A

Caffiiene

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16
Q

What is third line treatment for migraine?

A

triptans

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17
Q

What 5HT/triptan has longest half-life?

A

frovatriptam (Frova)

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18
Q

What 5HT/triptan is oldest and fastest acting?

A

sumatriptam (Imitrex)

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19
Q

What are common prophylactic meds for migraine?

A

beta blockers-propranolol and timolol; TCAs nortriptyline; ca channel blockers; NSAIDS

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20
Q

When should peds patients receive prophylactic treatment for migraine?

A

last 1-3 hours or >1 day

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21
Q

Differentiate generalized seizures from partial seizures

A

Partial seizures begin in localized area of brain and may cause no change in consciousness Generalized seizures involve both hemispheres of the brain and result in early loss of consciousness

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22
Q

What is the standard definition of status epilepticus?

A

Seizure activity persisting for more than 30 min or 2 or more sequential seizures without recovery between them

23
Q

When is drug therapy initiated in seizures?

A

After diagnosis is confirmed and pt has 2 or more seizures OR if pt has one or more risk factors for recurrent seizures

24
Q

What are risk factors for recurrent seizures?

A

EEG, structural lesion, partial seizures, family history

25
Q

What is first line treatment for seizures?

A

monotherapy based on type of seizure

26
Q

What is oldest AED?

A

phenytoin/Dilantin

27
Q

What is normal dosing of Dilantin?

A

5-6mg/kg/d in adults, 5-12 mg/kg/d peds

28
Q

What are adverse effects of dilantin?

A

gingival hyperplasia, hirsuitism, SLE, Hypotension

29
Q

What are special considerations with fosfophenytoin

A

use <5 days, after or during neuro surgery. 75mg=50mg phenytoin

30
Q

What meds are used in partial seizures

A

carbemazepine and oxcarbamazepine

31
Q

In what patients is valproic acid contraindicated

A

severe liver disease

32
Q

What is the first choice for absence seizures?

A

zarontin

33
Q

What are causes of major depressive disorder?

A

postpartum, SAD, dysthymia

34
Q

Why are SSRIs favorable in treating depression?

A

increased tolerability, decreased lethality

35
Q

what are potential side effects of SSRIs?

A

anxiety, insomnia, sexual dysfunction

36
Q

What are SNRIs?

A

effexor, cymbalta, Pristiq

37
Q

What is first line treatment for depression?

A

SSRIs

38
Q

What is second line treatment for depression?

A

other SSRI, SNRI

39
Q

What age group is prozac approved for?

A

ages 8 and up

40
Q

In treating anxiety, who is best treated by benzos?

A

Those with acute exogenous anxiety to time-limited stressor

41
Q

What med is used to treat benzo overdose?

A

mazicon

42
Q

What is the drug of choice for anxiety?

A

SSRIs

43
Q

What is first, second, and third line therapy for Generalized Anxiety Disorder?

A

SSRIs, Buspar, Benzos

44
Q

What is first, second, and third line therapy for panic disorder?

A

SSRI, TCA, MAOI

45
Q

what is first second line fro OCD?

A

SSRI, alternative SSRI

46
Q

What benzos are approved in peds?

A

diazepam, alprazolam

47
Q

What defines chronic insomnia?

A

> 3wks

48
Q

How do oral contraceptives affect benzos?

A

they decrease clearance of benzos

49
Q

What is half life of benzo receptor agonists?

A

5 hours

50
Q

What is first line for insomnia?

A

non-benzos

51
Q

What is second line for insomnia?

A

benzos

52
Q

What is third line for insomnia?

A

barbs, antidepressents

53
Q

what is first second and third line treatment for ADHD?

A

stimulants, non-stimulants/ antidepressant, bupropion

54
Q

What is first line treatment for alzheimers?

A

cholinestrase (aricept, cognex)