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Pharmacology > Unit 7-GU tract > Flashcards

Unit 7-GU tract Flashcards

1
Q

What is most causative agent in UTIs?

A

E coli 85-90% of the time

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2
Q

What are 3 symptoms of UTI?

A

urgency, frequency and dysuria

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3
Q

What are “uncomplicated” UTIs?

A

in premenopausal, sexually active females, not prego and no recent UTI

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4
Q

what are “complicated” UTIs?

A

post menopausal or prego female w/ h/o recent UTI, catheter, or GU defect. OR male

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5
Q

What is first line therapy for UTI?

A

3 day course of Bactrim

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6
Q

What is 2nd line for UTI?

A

flurooquinolones 3 days

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7
Q

How is bacterial vs nonbacterial prostatitis diagnosed?

A

bacterial w/ positive culture. nonbacterial w/ neg culture and positive WBCs.

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8
Q

What is first and second line for prostatitis?

A

1st: fluoroquinolones or bactrim. 2nd-doxycycline, azithromycin up to 12 wks

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9
Q

What are 5Alpha reductase inhibitors? What are the side effects?

A

proscar (finesteride) and Avodart (distasteride). Side effects are decrased libido, impotence

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10
Q

When are 5Alpha reductase inhibitors superior?

A

in larger prostates

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11
Q

What are alpha blockers? what are side effects?

A

terazosin, doxazosin, tamsulosin. decreased bp, fluid retention

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12
Q

what is first, second line to treat BPH?

A

1st: AUA score of 7. Alpha blockers OR 5ARIs

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13
Q

What is 1st and 2nd line tx for ED

A

1st: lifestyle, modify possible causes and start PDE5. 2nd: referral to urology

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14
Q

What do high fat meals potentially do to PDE5s?

A

decrease absorption

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15
Q

What are anticholinergics or anti muscarinics in OAB? when are they contraindicated?

A

oxybutynin etc. Contraindicated in narrow angle glaucoma

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16
Q

What is 1st and 2nd line therapy for OAB?

A

1st: anticholinergic 2nd: second anticholinergic

17
Q

What are symptoms of chlamydia in women?

A

either asymptomatic or c/o discharge, cervicitis, w/ edema and friability, PID

18
Q

What are symptoms of chlamydia in men?

A

epididymitis and ureteritis

19
Q

what is treatment of chlamydia?

A

azithromycin 1gm x1 or doxycyclin 100mg bid for 7 days

20
Q

what is treatment for chlamydia in prego?

A

emycin or amoxil

21
Q

What is treatment for gonorrhea?

A

125mg ceftriaxone of 400mg cefixipine PLUS chlamydia tx

22
Q

What are symptoms of syphilis?

A

ulcer or chancre at infection site (primary) or fever, malaise, sore throat, headache (secondary)

23
Q

what is first line tx for syphilis?

A

PCN. If allergic, doxycycline or tetracycline. if allergic in prego, desensitize et treat w/ PCN

24
Q

What is first line tx for herpes?

A

acyclovir 400mg tid for 7-10 days.

Pharmacology (11 decks)

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