Unit 6 Multiple Sclerosis Flashcards

1
Q

What are 4 primary motor impairments associated with MS?

A
  • decreased sensation
  • weakness
  • spasticity
  • intention tremor and ataxia
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2
Q

List 4 secondary symptoms?

A
  • contractures
  • UTI
  • skin breakdown –> ulcers
  • balance
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3
Q

Describe the most common type of MS?

A
  • Relapsing Remitting (RRMS)
  • attacks or exacerbations and remissions
  • about 85% of people
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4
Q

What is MS?

A
  • degenerative disease of the CNS
  • myelin sheath is “attacked”
  • commonly diagnosed between 15 and 40 years of age
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5
Q

Why do the symptoms vary so much among different people?

A
  • depends where in the brain is affected
  • not everyone has similar symptoms
  • individuals can present differently from one day to the next
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6
Q

What are possible psychological symptoms?

A
  • depression
  • dementia
  • psychosis (not very common)
  • seizures (not very common)
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7
Q

What is the cause of MS?

A
  • multi-factorial (depending on several factors or causes)
  • autoimmune system dysfunction
  • genetic predisposition
  • environment: early exposure to viruses
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8
Q

What are the 3 tests that are done to confirm the diagnosis of MS?

A
  • MRI
  • CSF: presence of proteins
  • Evoked potentials: look how fast the nerves are firing
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9
Q

What are the different types of MS?

A
  • Relapsing Remitting (RRMS)
  • attacks or exacerbations and remissions
  • about 85% of people
  • Secondary Progressive (SPMS)
  • Periods of relapses and remissions become less distinct over time
  • Primary Progressive (PPMS)
  • slow progression without remissions
  • about 10% of people
  • Progressive-Relapsing (PRMS)
  • Periods of attacks without remissions
  • Steadily worsening from beginning
  • Rarest form
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10
Q

What is the acute pathophysiology of MS?

A
  • degeneration of oligodendrocytes
  • ->demylination of white matter
  • ->inflammatory response

*Note: axon sparred

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11
Q

What happened in the later stage of pathophysiology of MS?

A
  • infiltration of macrophages
  • ->plagues (scar tissues)
  • axon damaged
  • ->atrophy of white matter
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12
Q

What are the implications for rehabilitation clinicians for OT?

A
  • Coordination ex.
  • AT device
  • Positioning
  • Mobility (w/c)
  • joint protection
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13
Q

What are the implications for rehabilitation clinicians for PT?

A
  • ROM
  • strengthening
  • stretching
  • gait training
  • balance
  • endurance
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14
Q

What are the clinical presentations of MS?

A
  • Symptoms increase with extreme temperature (very hot, very cold)
  • As it progresses, there are lasting and cumulative effects of the exacerbations (worsening)
  • Initial symptoms may include: fatigue, sensory and visual impairments (blurred vision or double vision)
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15
Q

What are the medical management for MS?

A
  • Symptomatic drug therapy
  • For example, to reduce spasticity or pain
  • Medications to slow progression
  • Immunosuppressive therapy to: decrease frequencies of relapses
  • slow progression
  • MS is complex and variable
  • interdisciplinary approach important
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