UNIT 4: Functions of the larynx and Vagus Nerve Flashcards

1
Q

for breathing the airway must be open at all ____ valves …. which are:

A

3

vestibule, false vocal folds, and true vocal folds

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2
Q

during quiet respiration the true VFs are in what position?

A

intermediate/paramedial position - abducted approx 8mm

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3
Q

during forced respiration the true VFs are in what position?

A

lateral position - w physcial exertion abduction width doubles

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4
Q

swallowing is a ____ function

A

protective - failure to protect lungs during swallowing is life-threatening

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5
Q

what must the larynx prevent during swallowing?

A

the entrance of any substance into the airway, as it would be harmful to the lungs

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6
Q

how do different parts of the larynx prevent substances from entering the airway?

A

true vocal folds adduct

false vocal folds approximate

arytenoid cartilages are drawn toward the epiglottis

larynx is pulled up against the base of the tongue

epiglottis is deflected

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7
Q

sneezing, coughing, lifting, defecating, and childbirth all require…

A

build up of alveolar pressure

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8
Q

following inhalation sufficient pressure is generated by _______ and _______ at level of the larynx (laryngeal closure) …. this is called the ______ ______

A

compression of the thorax

airway resistance

vaslsalva maneurver

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9
Q

the valsalva maneuver increases _____ _____ and can impede _________

A

intrathoracic pressure

venous return of blood to the heart (pressure on inferior vena cava)

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10
Q

during the Valsalva maneuver the _____ becomes a rigid frame so the forces applied for lifting for ex can be translated to the legs…. if the ____ is not fixed, ____ is depressed by the muscle forces intended for lifting ex.

A

thorax

thorax, ribcage

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11
Q

what is a cough, how is it innervated?

A

response of respiratory tissue to an irritant or foreign object

CN X - somatosensory innervation to bronchial mucosa and motor innervation to trachealis muscle

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12
Q

describe how coughing is a violent, broadly-predictable behaviour

A
  • deep inhalation thru widely abducted VFs
  • tensing and tight adduction of VFs, elevation of larynx
  • High Psub (relaxation pressure +m of expiration) blows VFs apart - maximal flow of air thru airway to clear irritant
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13
Q

If patients are coughing – what does this tell us?

A

something is going into their airway to stimulate this, we also know there is some preservation of sensory innervation, if they couldn’t feel it they couldn’t cough – even if swallow isnt working the best

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14
Q

chronic irritation from coughing leads to

A

vocal abuse due to excessive forces generated in coughing

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15
Q

we _____ the larynx for speech - biological functions of the larynx _____

A

borrow

take precedence

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16
Q

how do the VFs create phonation?

A
  • VFs are masses that can be set into vibration
  • VFs intrude into the airway (provides a source of turbulence in the vocal tract)
  • vibration of VFs is achieved by placing and holding VFs in airstream so their physical qualities interact w airflow causing vibration
  • VFs comprised of muscle and epithelial tissue that is capable of being moved when sufficient force is applied
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17
Q

bernoulli effect

A

given a constant volume of flow there will be a dec in pressure perpendicular to the flow and inc in velocity at a point of constriction in the flow

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18
Q

w the bernoulli effect, if the tube constricts the volume is the ____ and the velocity ____

A

same
increases

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19
Q

w the bernouli effect, if the rate of flow ____ at the point of constriction the pressure drops

A

increases

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20
Q

w the bernoulli effect, at the point of constriction the pressure will ____ and the velocity will ___ if volume is held constant

A

drop

increase

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21
Q

how does the bernoulli effect relate to vocal fold vibration

A
  • trachea and larynx are the tube
  • when the glottis is open and VFs are abducted, not sufficient construction
  • adducting VFs produces constriction
  • steady volume of air flow from lungs
  • benoulli –> low pressure bw VFs so they will be sucked toward midline
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22
Q

what is happening at the glottis during the bernoulli effect?

A

inc velocity and dec pressure bw folds - folds suck together when pressure drops

as folds contact, instantaneous pressure above VFs drops, while pressure below VFs inc

transglottal pressure differential inc

folds blow apart, air flow begins again

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23
Q

what is the myoelastic aerodynamic theory of VF vibration?

A

air stream passes bw folds

vibrate as a result of elastic quality of tissue interacting w aerodynamic principles embodied in bernoulli effect

frequency of vibration varies according to VF tension, mass, and elasticity of tissue

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24
Q

how is the valve sys of the VFs used for voiceless consonants?

A

laryngeal valve opened so that air may flow unobstructed into pharynx and oral cavity (where it is manipulated by articulators)

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25
Q

how is the valving of the VFs used for whispering?

A

edges of VFs of membranous glottis are stiffened, positioned apart to prevent vibration

vocal processes of arytenoids are toed in (LCA m)

cartilaginous glottis is separated posteriorly to form glottal chink (whisper triangle)

this glottal adjustment allows for air to flow thru the glottis into oral cavity w/o setting VFs into vibration

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26
Q

phonation can occur when the VFs are brought ______ _____ aka _______

A

brought together medially
aka adduction

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27
Q

phonation is the product of

A

repeated opening and closing of the glottis (i.e. repeated glottal cycles)

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28
Q

phonation is NOT the product of

A

repetitive adductions of the VFs

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29
Q

process of drawing the VFs apart to end phonation is

A

abduction

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30
Q

actual vibration of the VFs is the product of _____ interacting with ____ in the absence of ______

A

airflow
tissue
repetitive muscle contraction

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31
Q

general somatic afferent

A

pain, temp, mechanical stimulation of skin, muscles or joints

32
Q

special somatic afferent

A

vision and hearing

33
Q

general visceral afferent

A

sensation within viscera (ex. abdominal organs)

34
Q

special visceral afferent

A

taste and smell

35
Q

general visceral efferent

A

motor to glands, viscera

36
Q

general somatic efferent

A

motor to skeletal muscle (only CN XII)

37
Q

special visceral efferent (aka branchial motor)

A

muscles of branchial arch origin (larynx, pharynx, soft palate, face, jaw)

38
Q

what are the 5 fibre types in the vagus nerve CN X?

A

special visceral efferent (branchial motor)

general visceral efferent

general visceral afferent

special visceral afferent

general somatic afferent

39
Q

CN X special visceral efferent provides _____ innervation to …..

A

motor innervation to muscles in the pharynx and larynx

40
Q

what are the 3 major functions of CN X special visceral efferent fibers?

A

velopharyngeal port (need this to close or else we’d only have nasal sounds, liquids could also go into nasal cavity)

cross-sectional volume of the pharynx

positioning and tension of VFs

41
Q

for the SVE fibers of CNX the lower motor neuron has cell bodies where? where does the LMN receive info from?

A

nucleus ambiguus in medulla

receives info from motor cortex of both R and L hemispheres (Bilateral innervation)

42
Q

describe the intra-cranial pathway of SVE of CNX

A

axons leave nucleus ambiguus, exit medulla as 8-10 rootlets

all rootlets exit the skull thru jugular foramen to reach muscles of the palate, pharynx, and intrinsic muscles of the larynx

43
Q

describe the extra-cranial pathway of SVE of CN X

A

after emerging from the jugular foramen the vagus gives off…..

pharyngeal nerve, superior laryngeal nerve, recurrent laryngeal nerve

44
Q

pharyngeal nerve (Xph)

A

divides into pharyngeal plexus to supply muscles of soft palate and pharynx

45
Q

superior laryngeal nerve (SLN)

A

descends adjacent to pharynx; divides into internal (afferent) and external (efferent) SLNs; eSLN supplies cricothryoid muscle

46
Q

recurrent laryngeal nerve (RLN)

A

takes diff path on right and left sides of the body

47
Q

describe the two pathways of the recurrent laryngeal nerve - left and right

A

RIGHT: RLN branches from vagus anterior to subclavian artery … hooks under the subclavian artery and ascends posterior to it, in a groover bw trachea and esophagus

LEFT: RLN branches from vagus anterior to aortic arch …. hooks under arch abd ascends thru superior mediastinum to reach groover bw trachea and esophagus

48
Q

describe the intra-cranial pathway of general visceral efferent CN X fibers

A

cell bodies in dorsal motor nucleus (DMNX; gut, lungs, liver, pancreas) and medial nucleus ambiguus (cardiac plexus) in medulla –> fibres exit skull via jugular foramen

49
Q

the intra-cranial pathway of general visceral efferent CNX fibres are influenced by input from….

A

hypothalamus, olfactory sys, reticular formation, nucleus tractus solitarius (NTS)

50
Q

describe the extra-cranial pathway of CN X GVE (for pharynx and larynx/ thorax and abdomen)

A

Pharynx and larynx: axons are distributed to the pharyngeal plexus thru the pharyngeal and SLN branches –> secretomotor activation of glands in pharyngeal and laryngeal mucosa

thorax abdomen: secretomotor activation of glands and smooth muscle (esophagus, lungs, heart, stomach, liver etc)

51
Q

general visceral afferent fibres of CN X receive sensation from the ….

A

pharynx/larynx, trachea (caudal), esophagus, and thoracic and abdominal viscera

52
Q

CNX GVA: sensations from true VFs and below is in the ….

A

RLN

53
Q

CNX GVA: sensations from Larynx above the true VFs (ex. laryngeal vestibule, false VFs) is from the….

A

internal SLN (iSLN)

54
Q

CNX GVA: sensations from pharynx is in the ….

A

Xph

55
Q

CNX GVA also has sensation that drives 2 reflexes

A

gag reflex and cough reflex

56
Q

CN X GVA: describe the extra-cranial pathway of RLN

A

VFs and lower larynx –> cell bodies in inferior vagal ganglion

57
Q

CN X GVA: describe the extra-cranial pathway of iSLN

A

pharynx and upper larynx (above VFs) –> pierces thru the thyrohyoid membrane –> joins w eSLN to fomr SLN; SLN joins w RLN to form vagus –> cell bodies in inferior vagal ganglion

57
Q

CN X GVA: describe the extra-cranial pathway of Pharyngeal nerve

A

soft palate; joins SLN –> cell bodies in inferior vagal ganglion

58
Q

CN X GVA: describe the extra-cranial pathway of sensory fibres of vagus

A

pass into cranium via jugular foramen

59
Q

describe the intra-cranial course of CN X GVA

A

primary neurons synapse w secondary neurons in nucleus tractus solitarius in medulla

some secondary neurons synapse in hypothalamus, reticular formation and DMNX for parasympathetic reflexes (w visceral motor pathway)

60
Q

CN X special visceral afferent receives sensation from…

A

stretch receptors in walls of aortic arch, chemoreceptors in aortic bodies adjacent to aorta

taste receptors from pharynx, epiglottis, and laryngeal aditus

61
Q

describe the extra-cranial course for CN X SVA fibres

A

sensory fibres from heart converge w pharyngeal plexus

gustatory fibres from pharynx, epiglottis, and larynx converge w pharyngeal plexus

cell bodies of primary neurons are in inferior vagal ganglion

axons enter cranium thru jugular foramen

62
Q

describe the CN X SVA intra-cranial course (taste)

A

secondary neuron from NTS to thalamus

tertiary neuron from thalamus to insula

63
Q

CN X general somatic afferent carry what info

A

cutaneous sensations from skin at back of the ear and in the external auditory meatus, external surface of tympanic membrane

64
Q

describe the extra-cranial pathway of CN X GSA

A

primary neuron has cell bodies in superior vagal ganglion

65
Q

describe the intra-cranial pathway of CN X GSA (primary, secondary, tertiary neurons)

A

primary neuron –> axonal fibres travel to the CN V sensory sys

secondary neuron –> cell bodies in nucleus of spinal tract; axons ascend to contralateral thalamus

tertiary neuron –> cell bodies in thalamus axons tracel thru internal capsule to primary somatosensory cortex

66
Q

remember w embryogenic dev: 4th arch is _____ externally, 5th and 6th are _____, and 5th _____ in humans

A

visible
underdeveloped
disappears

67
Q

the Xph and SLN of the vagus comes from which arch?

A

4th

68
Q

the RLN of the vagus comes from which arch?

A

6th

69
Q

muscles of the palate/pharynx, and cricothyroid muscle comes from which arch?

A

4th

70
Q

intrinsic muscles of the larynx comes from which arch?

A

6th

71
Q

what skeletal and vasculature components come from the 4th to 6th arches?

A

skeletal - thyroid, triticial, arytenoids, cricoid, corniculate, cuneiform, epiglottis

vasculature - arch of aorta, pulmonary arteries

72
Q

what are the two things that need to be tested clinically for CN X?

A

velopharyngeal movement

laryngeal function

73
Q

how can you test velopharyngeal movement?

A

“ah” = look for symmetry and range of movement

asymeetry, uvula deviates on movement, swings toward the strong/intact side

gag reflex (sensory is Xph and CN IX; motor is Xph)

74
Q

how can you test laryngeal function?

A

“ah” max phonation time = perceptual judgement of hoarseness, breathiness, pitch breaks

cough (voluntary vs reflexive)