Unit 4 - Ch 11 - Mendelian Genetics Flashcards
Alleles definition
Alternate forms of a gene found on gene loci of homologous chromosomes
There are usually two alleles per trait (diploid)
Dominant alleles vs. Recessive alleles
Dominant
- expressed if present
- represented with capitol letters
Recessive
- expressed only if there’s no dominant alleles present
- represented with lower case letters
Genotype
Genetic makeup of an organism. Formed at conception, spread throughout cells of the body by mitotic cell division
Homozygous Dominant
Genotype where both alleles are dominant at gene locus (TT)
Example of pure breeding
Homozygous Recessive
Genotype where both alleles are recessive at a locus (tt)
Example of pure breeding
Heterozygous
Genotype where there is one dominant and one recessive at a gene locus (Tt)
= hybrid
Carrier of recessive traits
Phenotype
The expression of the genotype in an organism - often outwardly visible
Dominant phenotype
Expressed in homozygous dominant and heterzygous genotypes
Recessive phenotype
Expressed only in homozygous recessive genotypes
Mendel’s findings when breeding pea plants multiple generations ( P, F1, F2 )
- P - Parental
- crossed pure breeding pea plants with different expressions of the same trait - F1 - First filial
- showed all dominant phenotypes - F2 - Second filial
- produced by inbreeding F1 plants
- dominant and recessive phenotypes present, dominant was more common
Law of Segregation
Traits are determined by 2 factors (alleles) separating during gamete formation
- Mendel’s First Law
Formula for gamete formation
2(nth power) = # of different kinds of gametes
where n = # of heterozygous loci
Examples
TT = 2(0 power) = 1 unique gamete (T)
tt = 2(0 power) = 1 unique gamete (t)
Tt = 2(1st power) = 2 unique gametes (1/2 T and 1/2 t)
Phenotypic Ratio
(# dom. phenotypes) : (# rec. phenotypes)
= 3:1, 0:1, 1:0
Genotypic Ratio
HD : # Het. : #HR
= TtxTt = 3:1 phenotypic ratio, 1:2:1 genotypic ratio
Monohybrid Cross
The inheritance of two different alleles of a single locus
P gen: black f (BB) x brown m (bb)
F1 gen: will all be heterozygous (Bb), all black
F2 gen: Bb x Bb = 1//4 BB, 2/4 Bb, 1/4 bb
phenotypic ratio= 3:1
genotypic ratio= 1:2:1