Unit 2 - Ch 7 - Metabolism Flashcards
Types of metabolism
Catabolic and anabolic
Catabolism
3 and examples
-break down large molecules into smaller ones
- releases energy (exergonic)
- produces raw materials for anabolism
= hydrolysis, cellular respiration
Anabolism
2 and examples
-synthesize large molecules from small ones
- requires energy (endergonic)
= condensation, photosynthesis
ATP - Adenosine Triphosphate
- Adenine
- nitrogenous base
- also found in DNA and RNA - Ribose
- pentose sugar (5C)
Adenine+Ribose=Adenosine
- Phosphate Groups
- 3 phosphate groups
- stores and releases energy
How is ATP cycled in our cells?
Hydrolysis of ATP - ATP+H2O>>>ADP+Pi+Energy (i subscript = inorganic) - exergonic - ADP = adenosine diphosphate
Phosphorylation
- adding a phosphate group to a molecule
- ADP+Pi+Energy»>ATP
- endergonic
Exergonic reaction provide energy for endergonic
ATP is constantly cycled in our cells (100 lbs daily at rest)
What are the forms of oxidation? Is it exergonic or endergonic?
releases energy - exergonic
Forms
- Gain of O2 - historical basis
- Loss of e-
- Loss of H (1 proton & 1 e-)
(2 and 3 are common biological forms of oxidation)
Examples of oxidation
Wood, NAD & FAD
- Wood Combustion/Decomposition
Cellulose + O2»_space;> CO2 + H2O + Energy
- combustion requires activation energy making the reaction faster
- exergonic
- NADH»_space;> NAD+ + H+ + 2 e- + energy
- exergonic - FADH2»_space;> FAD + 2H+ + 2 e- + energy
- exergonic
Reduction forms?
Exergonic or endergonic?
endergonic - opposite of oxidation
Forms
- Loss of O2
- Gain of e-
- Gain of H (1 proton & 1 e-)
(2 and 3 are common biologically)
Examples of reduction of NAD & FAD
- NAD+ + H+ + 2 e- + energy»_space;> NADH
- FAD + 2H+ + 2 e- + energy»_space;> FADH2
right side: greater potential energy
coupled reactions
energy requiring reactions are linked (coupled) with energy releasing reactions
Examples of coupled reactions
- oxidation provides energy for reduction
- exergonic provides energy for endergonic
- ATP hydrolysis provided energy for phosphorylation
Coenzymes
- involved in oxidation / reduction reactions in organisms
- also cofactors for conjugated enzymes
A. NAD - nicotinamide adenine dinucleotide (requires niacin)
B. FAD - flavin adenine dinucleotide (requires riboflavin)
Metabolic Pathways. Importance and examples
Importance
- Allow Warm chemistry - vs. hot
- Precise regulation can occur - via enzyme regulation
Examples
1. Cellular respiration 2. Photosynthesis