unit 3 Flashcards
muscle twitch is ___ cycle of contraction and relaxation in a muscle fiber
one
- action potential arrives at the motor endplate ACH is released from motor neuron
- ACH binds to ligand gated NA+ channels in the motor end plate, generating an action potential along the sarcolemma
- action potential propagates along the sarcolemma down t tubules
- action potential causes voltage gated ca2_ channels in the sarcoplasmic reticulum to open
latent period/ lag
- ca2+ diffuses out of SR into sarcoplasm and binds to troponin
- active sites on the actin myofilament are exposed and the myosin heads bind to them
- cross bridge cycling begins and continues as long as ca2+ is in the sarcoplasm
contraction
- ca2+ is pumped from the sarcoplasm into the SR
- Ca2+ levels in the sarcoplasm declines and cross-bridge cycling comes to stop
relaxation
- length of sarcomere at the start of contraction
- frequency of stimuli
- muscle fatigue, temp, hydration
variables that affect twitch strength
- muscle size + fascicle arrangement
- which motor units are contracting
- total number of motor units contraction (recruitment or multiple motor unit summation)
variables affecting the whole muscle
allows only brief contraction
too short
too little overlap, weak contraction
too long
T/f muscles usually do not exceed length that leads to no tension produced:
- limitations on bone movements
- elastic filaments (titin)
- CNS monitors + adjusts muscle tones
- reflexive contraction
T
frequency of stimuli – if new stimuli arrive before the first is over, increase or decrease in tension?
increase
- become hyperpolarized –> muscle fiber less excitable
- accumulate ADP + inorganic phosphate –> slow cross bridge cycling, inhibits calcium release
short term muscle fibers fatigue
- fuel depletion –> less ATP made
- electrolyte loss through sweating
- central fatigue –> central nervous system produces less output to motor neurons
long term muscle fibers fatigue
animal naturally engage in variety of behaviors
natural variability
spinal cord arises form the ___ and ends at the ___ ____
brainstem; conus medullaris
spinal cord ends before the vertebral column (connection to the ____ punctures)
lumbar
Cervical + lumbosacral enlargements include neurons associations with the ___ (require more neurons with the limbs)
limbs
spinal cord has ____ grooves on anterior and posterior surfaces
- anterior median fissure (deep groove)
- posterior median sulcus (shallow groove)
longitudinal
specific bilateral region of skin supplied by a single pair of spinal nerves
dermatomes
areas where u find daily dendrites, cell bodies, an d unmyelinated axons
gray matter
areas where myelinated axons dominate
white matter
large bundle of nerve fibers
funiculus
- meninges
- CSF on subarachnoid space (shock absorption)
- vertebrae (structural protection)
- adipose (fat) in epidural space
structures protecting cord
** epidural space is where the epidural happens in ADIPOSE TISSUE and affects spinals roots and nerves and is different than lumbar punctures which is in the space of spinal fluid
ON EXAM
- protect damaging contacts with verebrae
- provide physical stability and shock absorption
- blood vessels in layers deliver o2 + nutrients to spinal cord
- continuous with cranial meninges
meninges
areas where you find mainly dendrites, cell bodies, and unmyelinated axons
gray matter
areas where myelinated axons dominate
white matter
large bundle of nerve fibers
funiculus
___ horns are only present in the thoracic and lumbar segments
lateral
___ neurons of the lateral horns are associated with autonomic division, innervate viscera
motor
- meninges, CSF in subarachnoid space, vertebrae, adipose (fat) in epidural space
protecting spinal cord
dense irregular connective tissue
dura mater
arachnoid mem = 5-6 layers squamous to cuboidal cells adhering to dura mater + loose cells, collagenous, + elastic fibers spanning to the subarachnoid space
arachnoid mater
delicate membrane of 1-2 layers simple to cuboidal cells = collagen & elastic fibers
pia mater
limit side to side movement of spinal cord
denticulate ligaments
carry sensory signals from the receptors to the CNS
afferent fibers
carry motor signals form the CNS to effectors
efferent fibers
innervate skin, skeletal muscles, bones, joints
Somatic fibers
innervate blood vessels, glands, and viscera
viceral fibers
innervate widespread organs such as muscles, skin, glands, viscera, and blood vessels
general fibers
innervate more localized organs in the head, including the yees, ears, olfactory, taste receptors, and muscles of chewing, swallowing, and facial expression
special fibers
individual axons are surrounded by endoneurium
loose connective tissue
bundles of axons (fascicles)
nerves
bundles of axons (fascicles) surrounding by ___
perineurium
nerve is protected form overstretching , injury by ____ = dense irregular connective tissue
epinerurium
Somatic motor neurons have their cell bodies in the _____ horns, axons go through ____ roots
anterior; anterior
autonomic motor neurons have their cell bodies in ___ horns, axons go through ___ roots
lateral; anterior
sensory neurons have their cell bodies in ___ root ganglia, axons either synapse within interneuron in the ___ horns or pass into ___ matter (ascending or descending tracts)
posterior; posterior; white
_____ branch reenter reentered the vertebral canal and innervates the meninges, vertebrae, and spinal ligaments
meningeal
smaller ____ ___ serve the back
posterior rami