Unit 2: Normal Human Microbial Flora Flashcards
Human Microbiome
Oral microbiome
Urigenital microbiome
Skin microbiome
Digestive tract microbiome
A collection of different microbes in an environmental system
Microbiome
types of organisms present in a specific environmental habitat
Microbiota
Some sites that provide favorable
conditions for microbial growth:
Anoxic and Oxic
obligately anaerobic bacteria
Anoxic
different kinds of microorganisms
Oxic
first line of defense against microbial pathogens
assist in digestion
toxin degradation
maturation of the immune system
Normal microbiota
SHIFTS IN THE NORMAL MICROBIOTA MAY CAUSE DISEASE.
_____ and _____ are not considered members of the normal microbial flora.
VIRUSES and PARASITES
Gastrointestinal microbiota
Helicobacter
Proteobacteria
Bacteroidetes
Actinobacteria
Fusobacteria
Firmicutes
_____ greatly colonizes the
stomach.
Helicobacter pylori
______,
______, and _____
dominate gastric
fluid samples.
Firmicutes, Bacteroidetes,
and Actinobacteria
_____ and _____ are more
abundant in gastric mucosal samples.
Firmicutes and Proteobacteria
_____ promotes the
growth of obligate
ANOXIA
anaerobes = ______
and _____
Clostridium and Bacteroides species
Bacteria = _____ of the weight of fecal matter
1/3
_____ contains microbial nutrients, but it is not a good microbial growth medium.
Saliva
_____ and ______ near teeth and gums create favorable conditions for extensive local microbial growth
Food particles and cell debris
habitat for species that grow as biofilms, e.g. Dental plaque
Oral cavity
Abundant bacterial genera in oral cavity
Streptococcus, Haemophilus,
Veillonella, Actinomyces, and Fusobacterium
Minor representation of Methanogenic Archaea and Yeast
Oral microbes
microbes bathed with secretions from the mucous membranes
Upper respiratory tract
Potential pathogens of upper respiratory tract:
- part of the normal microbiota in the
nasopharynx of healthy individuals
- do not normally develop disease
Staphylococcus aureus and Streptococcus pneumoniae
No resident microbiota
Lower Respiratory Tract
Pathogenic microbes (bacteria or viruses) = _____
Pneumonia