UNIT 2 IMMUNE SYSTEM Flashcards

1
Q

What are the 3 phases that happens when there is an infection local+systemic) ? 3

A
  1. Vascular
  2. cellular
  3. phagosytosis
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2
Q

in vascular phase what happens?

A
  • vasodilation
  • changes permeability endothelium
  • exudate = pus
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3
Q

what is an Edema?

A

-swelling of soft tissues as a result of excess fluid accumulation

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4
Q

what is exudate?

A
  • bigger molecules
  • due to tremors
  • hp> op plasma goes into interstitial space
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5
Q

what is transudate ?

A
  • EDEMA containing small mols

- hp

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6
Q

what is?

  1. serous exudate =
  2. purulent exudate =
A
  1. plasma, proteins few leukos, transparent

2. Purulent exudate - a lot leukos, green + bacteria

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7
Q

which chemical mediators are vasodilators?

A
  1. PG1+2

2. histamine (usually allergies)

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8
Q

what is arachoic acid made of?

A

LT + PG (+PG2txa2)

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9
Q

what does Txa2 do?

A

promotes aggregation of platelets

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10
Q

what do cytokines do?

A

in inflammation + immunity - IL-1 + 6

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11
Q

antiinflammatory drugs?

steroids

A

STEROIDS

  • blocks both pg +lt
    1. cortisol, cortisone, presione
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12
Q

antiinflammatory drugs NSAIDS?

A

blocks only pg

1. paracetamol, ibuprofin and aspirin

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13
Q

NSAIDS characteristics?

A
  1. antiinflam
  2. anti analgesic =pain
  3. antipyretic =fever
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14
Q

aspirin is what?

A

ANTIPLATLETS

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15
Q

What is cyanosis?

A

blue colour = blood loss

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16
Q

chemical name for paracetamol?

A

ACETAMINOPHEN

17
Q

chemical name for aspirin?

A

acetylsalic acid

18
Q

what does pyrogen do ?

A

bacteria, acts on thermoregulatory center , makes you feel 40deg really 37, = shiver = vasoconstriction to match brain

19
Q

what is toxoplasma?

A

parasite in blood from CATS, uncooked meat, contam water

20
Q

what is HLA?

A

histocompatiblity leukoctye antigen

  • all cells have same hla
  • important in transplantation
  • some cells have special Hla (diabetes)