Unit 2 - Drug Class NS: Pain Management

Question 1

Opioid Analgesics Agonist

Action, Uses, Drugs

Answer 1

Action: Act by stimulating the opiate receptors in the CNS. Relieve serve pain without loss of consciousness by blocking pain sensation
Agonist: Binds
Partial Agonist: Binds to a pain receptor but causes weaker response
Antagonist: Binds to a pain receptor but does not reduce pain signals.

Uses: Relieve acute or chronic moderate to severe pain such as accosted with acute injury, post op pain, renal or biliary colic, MI, or cancer.

Drugs: Morphine, Hydromorphone, Codeine

Question 2

Non-Opioid Analgestics

Actions, Uses, Drugs

Answer 2

Action: Disrupting the production of prostaglandin, an important mediator of pain and inflammation

Uses: Commonly used to treat mild and moderate acute and chronic pain.

Drugs: Acetaminophen,

Question 3

Salicylate Agents

Action, Uses, Drugs

Answer 3

Action: Inhibit prostaglandin synthesis
3 pharmacological: analgesic, antipyretic, anti-inflammatory
Inhibiting platelet

Uses: Pain relieving, anti-inflammatory, and antipyretic effections.
Headaches, muscle aches, arthritis
Reduces risk of MI, TIA, Stroke

Drugs: Acetylsalicylic Acid

Question 4

NSAIDS

Actions, Uses, Drugs

Answer 4

Action: Prostaglandin inhibitors. Varying degrees of analgesic, antipyretic, and anti inflammatory activity.
Blocks COX-1 and COX-2

Uses: Used to relieve pain and inflammation of rheumatoid arthritis, osteoarthritis, ankylosis spondylitis, and gout.
Minor aches and pains

Drugs: Aspirin, Ibuprofen, Ketorolac

Question 5

Opioid Analgesics Antagonists

Action, Uses, Drugs

Answer 5

Actions: Binds to opiate receptors and prevent a response

Uses: Overdose

Drugs: Naloxone
IV: Effects begin immediately and lasts 1 hour
IM and SC: begins 2-5 mins after dose, several hours
Half life: 2 hours