Unit 2: 5 - Musculoskeletal Neoplasia Flashcards
What is a primary bone tumor?
Arises from bone itself
What is a secondary bone tumor?
It is metastatic to the bone
What is the most common primary bone tumor in dogs?
Osteosarcoma (85%)
What age dogs get osteosarcoma?
There is a subset of juveniles that get it (18-24 months)
But the majority are 7-10 years old
What breeds predominantly have osteosarcoma?
Large and giant breeds;
It is rare in cats
What is the prevalence of osteosarcoma in the appendicular, axial, and extraskeletal locations in the dog?
Appendicular (75%) > Axial (25%) > Extraskeletal
What specific locations is osteosarcoma most commonly found in in dogs?
Distal radius and proximal humerus
Where on the bone does osteosarcoma prefer in dogs?
Metaphysis
What does it mean when we say that osteosarcoma is monostotic?
It is limited to one bone
Generally, we can say that osteosarcoma in dogs likes to be _____ from the elbow and _____ the knee.
away, towards
Other than the distal radius and proximal humerus, what are 2 other locations where osteosarcoma can be found in dogs?
Distal femur, proximal tibia
T/F: Osteosarc is highly metastatic in dogs.
True
>90% of osteosarc metastasis is to the _____ in dogs.
lungs
Osteosarc is the most _____ bone neoplasm in cats, but it is still _____ overall.
common, rare
What is the prevalence of appendicular vs. axial osteosarc in cats?
Appendicular (50-60%) > Axial (40-45%)
What is the metastatic rate of osteosarc in cats?
10%
What is the prognosis for osteosarc in cats?
Prolonged survival with amputation alone (>64 months)
Which location in cats has a worse prognosis for osteosarc?
axial
What is the most common location for a chondrosarcome?
tibia
What are 2 differentials for secondary bone neoplasia?
- Multiple myeloma
- Carcinomas
What neoplasms are polyostotic and what does this mean?
Joint neoplasms;
Can be involved with more than 1 bone
What are the 3 common joint neoplasms?
- Synovial cell sarcoma
- Histiocytic sarcoma
- Synovial myxoma
Where do synovial cell sarcomas like to grow and what breeds are prone to these?
Elbow and stifle;
Golden Retrievers
What is the metastatic rate for histiocytic sarcomas?
What breeds are prone to getting them?
High;
Rottweilers, Bernese Mountain Dogs