Unit 12: Human Reproduction Flashcards
What is Digital Rectal Exam (DRE) for?
to early detect prostate cancer
What is a self exam for?
to early detect breast cancer
What does a self exam reveal?
may reveal new hard spots or lumps in the breast
What is a mammogram? used for?
x-ray of the breast used to detect bumps too small to feel bumps and help distinguish if bump is breast cancerous
What’s the purpose of BRCA1 & BRCA2 gene?
to see if a patient inherited genes that are premutated.
Mutated copies of _____ gene makes it likely to develop ____ cancer?
Mutated copies of **BRCA1 & BRCA2** gene makes it likely to develop **breast** cancer
What is a pap smear for?
to detect cervical cancer
How does a pap smear work?
Swab the mucous (黏黏)of the cervix (mucous contains cells of cervix). cells observed to see if any are cancerous
Why is radiation therapy not needed for grandpa with prostate cancer?
- expensive and painful - doctors know that prostate cancer grow very slowly, most men die from other problems - against strong statistics -> not necessary!
Why is biopsy unnecessary for woman with small hard spots in breast?
- doctors know based on statistics, hard spots are usually not tumorous (if they are, they’re likely not cancerous 2. Woman is upset cause she must wait a month for a biopsy but they were just dense, non cancerous tissue
how do US medical care make profit by overtreating?
- grandpa with prostate cancer recommended radiation therapy
- woman recommended biopsy after having small hard spots on the breast because they’re usually non cancerous dense tissue
What is biopsy?
The removal of a small piece of tissue for examination
What are stem cells?
unspecialized cells that can differentiate into specialized cells
What is the most potent (most powerful) type of stem cell?
Embryonic stem cells - they can become any cell type in the body
What cells are less potent and able to differentiate into a more LIMITED range of cell type?
Adult stem cells
Why are adult cells less potent?
they can only differentiate to a more LIMITED range of cells
What can adult stem cells do in the bone marrow?
differentiate into platelets, red blood cells, and some white blood cells but NO OTHER CELLS
What cells are great value to research and medicine?
Embryonic stem cells
Why are embryonic stem cells important?
they are great value to research and medicine
How can stem cells be used?
to THERAPEUTICALLY treat human disease & correct genetic mutation
How did Stargardt’s Disease get treated with stem cells?
- DIFFERENCIATED skin cells taken from patient
- reprorammed to be stem cells (by iPSC)
- genetically edited to not have mutation and cultured outside the body to be new retinal cells for the mascula
- cells transplanted to patient’s retina to repair mascula and repare sight
What is Stargardt’s Disease?
a type of mascular degernation caused by a mutation that causes mascula cells to degenerate (decline) - lose most of focused sight and color vision
what has been steadily dropping since the mid 20th century?
male fertility
Why has male fertility been declining? correlated with?
correlated with - increase in plastics - variety of synthetic compounds that are hormones (ex: birth control)
Why do plastics decrease male fertility?
plastics shed hormone like chemicals into the body & environment
What is infertility?
The inability to conceive after 1 year of trying