Unit 1.2(bii) - Proteins, Synthesis of membrane compartments Flashcards
Where are lipids synthesised?
Lipids are synthesised in the smooth endoplasmic reticulum (SER) and inserted into its membrane
Where does the synthesis of all proteins begin
Cytosolic ribosomes
What happens to cytosolic proteins?
They are synthesised in cytosolic ribosomes and then remain in the cytosol
What is Post-translational Modification?
Either the addition of a chemical group to a protein or covalent cleavage of the polypeptide.
When does post-translational modification take place?
After translation of the protein
Where does post-translational modification take place?
In the RER, golgi apparatus and target site of protein
What do trans-membrane proteins do?
They carry a signal which halts translation and tells the ribosome to dock with the ER
What happens after the ribosome has docked with the ER
Translation of the protein continues and is then inserted into the membrane of the ER
