Unit 1 - Topic 2 - Proteins - Section B - The synthesis and transport of proteins - Part IV - The secretory pathway Flashcards
Where are secreted proteins translated
Secreted proteins are translated in ribosomes
on the RER and enter its lumen
Examples of secreted proteins
Peptide hormones and digestive enzymes
Where do the proteins go and what happens to them after this
The proteins move through the Golgi apparatus and are then packaged into secretory vesicles
These vesicles move to and fuse with the and what does it release
These vesicles move to and fuse with the plasma membrane, releasing the proteins out of the cell
What are many secreted proteins synthesised as
Many secreted proteins are synthesised as inactive precursors and require proteolytic cleavage to produce active proteins
What is proteolytic cleavage and what are digestive enzymes an example of
Another type of post-translational modification. Digestive enzymes are one example of secreted proteins that require proteolytic cleavage to become active.