Unit 1: S-S systems pgs 17-45 Flashcards
Anatomically: Precuneus
Functionally: ?
S-S Association Cortex
Anatomically: Superior Parietal Lobule
Functionally: ?
S-S Association Cortex
Define sterognosis:
3-D knowledge
recognition/identification of an object held in the hand with eyes closed
What is Graphestheia
Traced figure ID
Anatomically: post-central gyrus
Functionally: ?
1˚ S-S Cortex
Specifically: Face, Upper extremity, Trunk
What is the 1˚ S-S Cortex comprised of?
Face
Upper extremity
Trunk
Lower extremity and perineum/pelvis
Anatomically: posterior paracentral lobule
Functionally: ?
1˚ S-S Cortex
Specifically: Lower extremity and perineum/pelvis
Two main pathways for somatosensory systems:
Spinothalamic tract = anterolateral system
Medial lemniscus system = dorsal/posterior column system
What tract monitors nociceptors, temperature, light/non-discriminative touch
Spinothalamic tract = anterolateral system
What is Agnosia
Without knowledge
‘A’ without
‘Gnosia’ knowledge
What is tactile agnosia
Inability to appreciate tactile info — cannot do 2-point discrimination, texture
What is agraphesthesia
Inability to recognize traced pattern on skin
What is Astereognosis
Inability to recognize an object held in the hand — size, shape, weight, etc
What system monitors: fine/discriminative touch, proprioception info and vibration
Medial lemniscus system = dorsal/posterior column system
What receptors are: unencapsulated free nerve endings, group Adelta (type III) fibers and group C (type IV) fibers, and monitors noxious stimuli (mechanical, thermal or chemical)?
Nociceptors
What receptors are ambiguous, include free nerve endings, group Adelta (type III), group C (type IV) fibers, monitor cool and warm temps (non-noxious range)
Temperature receptors
What receptors include unencapsulated and encapsulated nerve endings, group Adelta (type III), group Abeta (type II) fibers, and monitor tactile info?
Crude touch receptors
What is the kind of pain that is immediate, sharp, well-localized? Aka discriminate pain perception
Fast pain (nociceptors)
What is pain that is slower onset, dull, diffuse? Aka non-discriminate pain perception
Slow pain (nociceptors)
What is an important interneuron that is able to modify nociception pathways?
Lamina II - substantia gelatinosa
terminals of axons that lie next to cells or free in the extracellular space
unencapsulated endings
Which receptors have unencapsulated endings?
- free nerve endings
- Merkel discs/endings
- peritrichial nerve endings
terminals of axons enclosed by a capsule of non-neuronal cells
encapsulated endings
Which receptors have encapsulated endings?
- Pacinian corpuscles
- Meissners corpuscles
- Ruffini corpuscles/
endings - End bulbs (of Krause, Golgi-Mazzoni, etc.)
- neuromuscular spindles
- neurotendinous spindles
axon terminals that are located between cells in many tissues
free nerve endings
Axon terminals associated with special cells that are located in deep layers of the epidermis and primarily found in glabrous skin
Merkel discs/endings
axon terminals that are distributed along the root of a hair follicle
peritrichial nerve endings
single axon terminal with layers of
non-neuronal cells
Pacinian corpuscles
highly branched axon inside a capsule that is long and slender
Meissners corpuscles
single axon inside delicate
capsule
Ruffini corpuscles/ endings
Axon of variable sizes and shapes • often round/ circular • contain single highly-branched axon • often found at muco-cutaneous junctions
End bulbs (of Krause, Golgi-Mazzoni, etc.)
axons located in skeletal muscle
neuromuscular spindles
Axons located in tendons, ligaments
neurotendinous spindles
Receptors in cutaneous areas
- free nerve endings
- peritrichial endings
- Merkel discs/endings
- Ruffini endings
- Meissners corpuscles
- pacinian corpuscles
Where will you find free nerve endings in the cutaneous areas?
found in (deep) epidermis, dermis, subcutaneous tissue and monitor thermal, noxious and tactile stimuli
Where will you find peritrichial endings in the cutaneous areas?
monitor movement of hair (tactile)
Where will you find Merkel discs/endings in the cutaneous areas?
found in deep layers of epidermis (tactile)
Where will you find Ruffini endings in the cutaneous areas?
found in dermis, subcutaneous tissue (tactile - especially stretch)
Where will you find Meissners corpuscles in the cutaneous areas?
found in dermal papillae of mainly glabrous (= hairless) skin; especially fingertips • tactile receptor
Where will you find pacinian corpuscles in the cutaneous areas?
found in dermis, subcutaneous tissue (act as mechanoreceptors, esp. for vibration)
Receptors in joints have what kind of nerve endings?
- free nerve endings
- small pacinian corpuscles
- Ruffini-like endings
- neurotendinous spindles (Golgi tendon organs)
What kind of receptor nerve endings are found in skeletal muscles?
- free nerve endings
- neuromuscular spindles
Where in joints would you find free nerve endings?
in synovial membrane, joint capsule and periarticular CT
Where in joints would you find small pacinian corpuscles?
in periarticular CT around the joint capsule
WHere in joints would you find Ruffini-like endings?
in joint capsular tissue
Where in joints would you find neurotendinous spindles (Golgi tendon organs)?
in articular ligaments
Where in skeletal muscle would you find free nerve endings?
mainly associated with connective tissue
around muscle tissue
Where in skeletal muscles would you find meuromuscular spindles?
distributed mostly in muscle near its junction with tendon and most numerous in muscles that perform highly skilled maneuvers (e.g., hand)
What kind of receptors would you find in tendons?
- free nerve endings
- Golgi tendon organs (GTOs)
What kind of receptors would you find in the viscera?
- free nerve endings
- pacinian corpuscles
The pathway for sensory modalities of discriminative touch, vibration (not exclusive), and proprioception (although the pathway for proprioception is a bit different and will be described separately)
Medial Lemniscus System aka Dorsal/Posterior Column System
Qualities of discriminative touch include
- recognize precise location of a tactile stimulus
- 2-point discrimination - permits recognition of different textures
- graphesthesia- identify a familiar pattern when traced on skin
Qualities of proprioception include:
- information regarding the precise position of a body part (without visual aid), and the range and direction of movement (kinesthesia)
- also permits one to appreciate the shape, size and weight of objects (held in the hand)
Qualities of vibration include:
sensation of an oscillating mechanical stimulus elicited by a tuning fork (128 Hz) set in motion and placed on the body
Primary neurons for the medial lemniscus system are located where?
Dorsal root ganglia
The central processes of primary neurons for the medial lemniscus system enter the ipsilateral ________ and branches into________ and _______ collaterals
dorsal funiculus
ascending
descending
Short ascending and descending collaterals from the central processes of primary neurons for the Medial Lemniscus System synapse _________ and modify __________.
- spinal cord gray matter
- cord mediated activity - i.e., reflexes, sensory and motor activity
Long ascending collaterals from the central processes of primary neurons for fine touch and vibration for the body in the Medial Lemniscus System that enter cord below T6, project through the ipsilateral _______ to synapse in the nucleus gracilis on the ________ surface of the medulla
- fasciculus gracilis
- dorsal/ posterior
In the Medial Lemniscus System (fine touch and vibration for body), fibers that enter the cord above T6 project through the ipsilateral _________ to synapse in the__________ on the dorsal/ posterior surface of the__________.
fasciculus cuneatus
nucleus cuneatus
medulla
Nucleus gracilis and cuneatus are located where?
Medulla
Nucleus gracilis and cuneatus receive information that originated from where?
The ipsilateral lower body and upper body respectively
Fibers for fine touch and vibration of the medial lemniscus tract do what after synapsing on secondary neuron cell bodies in nucleus cuneatus and nucleus gracilis?
They decussate and form a fiber tract called the medial lemniscus that ascends on the contralateral side of the brain stem
The secondary fibers of medial lemniscus tract ascend through the medulla, pons and midbrain to synapse on tertiary neurons (Except for lower body proprioception which have quaternary neurons) in the ________ of the thalamus
ventral posterior lateral (VPL) nucleus
Long ascending collaterals from the central processes of primary neurons for upper body proprioception in the Medial Lemniscus System that enter cord above T6, ascend through the ipsilateral _______ to synapse in the nucelus _______ on the ________ surface of the medulla
Fasciculus cuneatus
Cuneatus
Posterior
Long ascending collaterals from the central processes of primary neurons for lower body proprioception in the Medial Lemniscus System that enter cord below T6, ascend through the ipsilateral _______ to synapse in the nucelus _______.
- Fasciculus gracilis
- Dorsalis (AKA Clarke’s nucleus)
Clarke’s nucleus is located where in the spinal cord grey matter? At what cord segment levels?
- in Lamina VII of the spinal cord gray matter
- in cord segments C8-L3