Unit 1 - Intro to Physiology Flashcards

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1
Q

The wall of the alveolus (air sac) in the lung is composed of which type of epithelium?

A

simple squamous epithelium

This single layer of squamous cells is ideal for the diffusion of gases in the lungs.

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2
Q

The proximal tubule of the nephron in the kidney is composed of which type of epithelium?

A

simple cuboidal epithelium

Simple cuboidal cells line the kidney tubules (nephrons) so that secretion and absorption can take place.

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3
Q

The epithelium of the esophagus is composed of which type of epithelial tissue?

A

stratified squamous epithelium

This epithelium protects underlying tissues from the wear and tear of constant swallowing in the esophagus.

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4
Q

Which part of the neuron (a specialized nerve cell) receives signals from other cells and is also the main metabolic region of the neuron?

A

soma

The soma or cell body receives inputs (signals) from other cells and sends the information to the axon. But unlike a dendrite, it is also the main metabolic and nutritional center of the cell.

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5
Q

Which of the three muscle cell types has multiple nuclei?

A

skeletal

Skeletal muscle cells are elongated and many can be quite long; therefore, they have multiple nuclei.

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6
Q

Which muscle cell type has visible striations but is not under voluntary control?

A

cardiac

Cardiac cells, like skeletal cells, have visible striations but are not under voluntary control.

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7
Q

What is excitable tissue?

A

Excitable tissue is made of cells that can alter their membrane potentials in response to a stimuli and generate action potentials. Excitable cells include neurons, muscle cells, and beta cells of the pancreas.

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8
Q

Which form of cell-to-cell communication uses the direct transfer of electrical and chemical signals?

A

Gap-junction signaling

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9
Q

What is the name for a competing ligand that binds to a receptor and causes the same response as the primary ligand?

A

agonist

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10
Q

Neurons that lie entirely within the CNS are called?

A

interneurons

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11
Q

Which glial cells have extensions that contact blood vessels in the brain?

A

astrocytes

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12
Q

A collection of neuronal soma in the PNS (outside the CNS) is called a _______ and within the CNS is called a _______.

A

ganglion (pl. ganglia); nucleus

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13
Q

Concentration gradients exist across the cell membrane. Specifically, there are more ________ inside and more ________ outside the cell membrane.

A

K+ ions; Na+ ions

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14
Q

The plasma membrane of a neuron is more permeable to _________.

A

Potassium (K+) ions

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15
Q

Resting membrane potential being negative (-70 mV) depends on what factors?

A

-the greater number of potassium leak channels
-the greater permeability of the plasma membrane to K+ ions
-the concentration gradient for Na+ ions

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16
Q

A neuron under the influence of a neurotransmitter that opens K+ ion
channels will ______________.

A

be less likely to fire an action potential

17
Q

An action potential starts at the trigger zone of efferent neurons & interneurons. This is the _______ and _______.

A

the axon hillock; initial segment

18
Q

In myelinated axons, action potential occurs at the ________ and they propagate ________.

A

nodes of Ranvier; rapidly

19
Q

Action potential propagation in myelinated axons is known as
________.

A

saltatory conduction

20
Q

This type of tissue provides structural support and barriers.

A

connective tissue

21
Q

How do neurons transmit electrical impulses?

A

via energy stored as an electrochemical gradient

22
Q

Initiating ions to enter a cell is accomplished through the binding of ____________ to __________ ___________ that open _____ ___________.

A

neurotransmitters; membrane receptors;
ion channels

23
Q

How does the membrane potential return to the resting level?

A

K+ ions leave the cell (falling phase of action potential)

24
Q

Why can’t an action potential be generated during the absolute refractory period?

A

The Na+ channel is in an inactive state

The membrane must depolarize before the Na+ channel can return to its normal resting state

25
Q

Why does it take a suprathreshold stimulus to generate an action potential during the relative refractory period after hyperpolarization?

A

K+ channels are still open, so more Na+ is needed to reach threshold stimulus

26
Q

Why is the refractory period important?

A

It sets the direction for the flow of current, prevents temporal summation and prevents the action potential from going backwards.

27
Q

What determines how fast an action potential can travel along a neuron?

A

-diameter of the axon
-resistance of the axon membrane to ion leakage out of the cell (insulating the axon using myelin sheath reduces ion flow out of cell and speeds conduction)