Unit 1: Control of the Cell Cycle Flashcards
The control of the cell cycle can be studied using model organisms such as?
Yeast
When does the G1 checkpoint take place?
At the end of G1 before S phase
When does the G2 checkpoint take place?
At the end of G2 before the start of the M-phase
When does the M checkpoint take place?
Before the beginning of anaphase
What is checked for at the G1 checkpoint?
Cell size and environmental conditions
What is checked for at the G2 checkpoint?
Correct replication of DNA
What is checked for at the M checkpoint?
Chromosomes correct attachment to spindle fibres
Cells need an adequate nutrient supply to proliferate, plus what else?
Serum
Serum needed for cell proliferation contains a protein causes what to happen?
It stimulates the cells to continue through the cell cycle
Extracellular signal molecules with the ability to stimulate the cell to continue the cell cycle are called?
Mitogens
Mitogens are?
Extracellular signal molecules with the ability to stimulate the cell to continue the cell cycle
In the absence of Mitogens what happens to the cell cycle?
Cells in the cycle enter the G0 phase
What happens in the G0 phase of the cell cycle?
Cells don’t divide
For how long do the cells remain in the G0 phase of the cell cycle?
They can remain here forever or re-enter the cell cycle when appropriate.
Give two examples of cells than can proliferate continuously
Stem cells and Tumour cells
