Unit 1 Flashcards
Innate immunity
-intrinsic
-always present
-unspecific
-lack immunological memory
-immediate response
Acquired immunity
Specific recognition
Need a prior infection
Improves on repeated exposure
Immunological memory
Stages of specific immunity
Recognition
Activation
Response
Description granulocytes
Large cytoplasmic granules
Polylobed nucleus
Types granulocytes
Neutrophils
Basophils
Eosinophils
Granular leukocytes
Granulocytes
Mast cells
Agranulocytoses
Description agranulocytoses
Small granules
Rounded nucleus
Types agranulocytoses
Monocytes
T cells
B cells
Natural killers
What happens in primary lymphoid organs
Development and maturation of lymphocytes
What happens in secondary lymphoid organs and tissues
Where mature lymphocytes and antigens meet
B lymphocytes mature in
Bone marrow
T lymphocytes mature in
Thymus
What are the secondary lymphoid organs and tissues
Spleen
Lymph nodes
Mucosal Associated lymphoid Tissue MALT
MALT
Mucosal associated lymphoid tissues
What happens in the Spleen
Defense against antigens in blood
What happens in Lymph nodes
Interaction of circulating antigens from tissues with phagocytes
What happens in MALT
Capture of antigens from urinary, gastrointestinal and reproductive tracts
Antigen
Substance that is recognized as foreign and triggers an immune response
Immunogenicity
Ability of a substance to trigger an immune response
Antigenicity
Ability to be specifically recognized by the antibodies generated by the immune response
Antibodies synonym
Immunoglobulin
Antibodies
Substance that binds to and kill a specific antigen
Natural barrier definition
Mechanisms inherited as part of the innate structure
Natural barrier types
Biological
Chemical
Physical
Biological barrier
Microbiota
Flora
Physical barrier
Mucus
Skin
Secretions
Beating cilia
Chemical barrier
Acid pH in vagina and stomach
Lysozyme in tears and saliva
What does the Immune defense start
Once the pathogen has entered the body
2nd line of defense
Innate immunity
3rd line of defense
Acquired immunity
