Ulcerative lesions Flashcards
What are THREE differences of acute and chronic traumatic lesions?
- Pain vs. not painful (chronic)
- Margins red vs. elevated (chronic)
- Surface covered in yellow exudate vs. indurated (chronic)
Traumatic eosinophilic ulcer:
- Clinical presentation
- Histology
- Chronic ulcer 1-2cm (months, often heals quicker after biopsy)
- Lots of eosinophils and macrophages
How do you identify granulation tissue histologically?
Immature fibroblasts, vascular, lots of inflammation, layer of dead cells on surface.
NOTE: immature fibroblasts have plump nuclei (forming lots of collagen), while mature ones have squished nuclei.
Traumatic eosinophilic ulcers, major aphthous ulcers and malignant (endophytic) lesions all have similar clinical presentation. What is one way to differentiate them? (not histologically)
Apply topical corticosteroid to them. Malignant lesions will not heal after a few days like the others will.
Differentiate between minor, major and herpetiform ulcers.
- Size: minor (5-7mm), major (cms), herpetiform (1-2mm, may coalesce)
- Healing: minor/herpetiform (5-7 days), major (months)
One tip for applying Kenalog orabase?
Dry area before application.
Crohn’s disease in a type of inflammatory Bowel Disease.
What are THREE extraoral features of Crohn’s disease and FOUR oral features?
Extraoral (diarrhoea/constipation, abdominal pain, malabsorption)
Intraoral (fibroepithelial polyps, ulcers, diffuse lip swelling, glossitis)
NOTE: histologically lots of granulomatous inflammation
Anaemia (lack of RBCs) can cause aphthous ulcers and glossitis. What are TWO types of anaemia?
- Iron deficiency
- Pernicious (lack of B12 and folate)
What is Epidemolysis Bullosa?
Genetic condition where desmosomes are broken down leading to loss of epithelium attachment -> ulceration
Behcets Disease:
- Prevalent in who?
- Ulceration where?
- Cause? is it contagious?
- Treatment?
- Males, 20-40yo
- Ulcers in mouth, eyes, genitals
- Unknown, maybe genetic. Not contagious.
- Management of Sx
