UI Flashcards

1
Q

How does the following drug class cause OAB symptoms?

opiates

A

opiates

less awareness of bladder filling, increased sphincter tone, fecal impactions

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2
Q

How does the following drug class cause OAB symtpoms?

sedatives

A

Sedatives

impaired detrusor contraction

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3
Q

How does the following drug class cause OAB symtpoms?

anti-histamines

A

potential for decreased contractility

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4
Q

How does the following drug class cause OAB symtpoms?

anti-depressants

A

anti-depressants

duloxetine, TCAs

increased sphincter tone, decreased bladder contractility

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5
Q

How does the following drug class cause OAB symtpoms?

anti-psychotics

A

anti-psychotics
clozapine, olansapine, risperidone

CNS stimulation, decreased sphincter tone, decreased contractility

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6
Q

How does the following drug class cause OAB symtpoms?

alpha agonists

A

alpha agonists

meythl-dopa, clonidine

urinary retention, increased sphincter tone

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7
Q

What is the questionnaire measuring and how is it scored?

IIQ- impact of incontinence

A

affect of incontinence on daily habits and emotional status

score 0-100

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8
Q

What is the questionnaire measuring and how is it scored?

UDI urogenital distress inventory

A

which sx are most bothersome?
-frequency/urgency/incomplete emptying
-SUI
-Pain

raw score x 25

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9
Q

What is the questionnaire measuring and how is it scored?

PFDI

A

all pelvic floor dysfunction (urinary, fecal, prolapse)

0-300, raw score x 25

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10
Q

What is the questionnaire measuring and how is it scored?

PISQ

A

sexual impact of pelvic floor disorders

multiplying the number of items by the mean of responses

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11
Q

what is the success rate of bulkamid?
improved vs dry

A

70% improved
40% dry

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12
Q

DDX for UI?

A

structural vs nonstructural:
ectopic ureter, urethral diverticulum, fistula, UUI, MUI, SUI

GU vs non-GU:
dementia, neurologic conditions, UTI, GSM, stool impaction, limited mobility, DM, medications, SIADH

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13
Q

What percentage of patients will stay on an anticholinergic for more than year?

A

50%

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14
Q

What percentage of patients will stay on an anticholinergic for more than year?

A

50-75%

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15
Q

How does desmopressin reduce nocturia?

A

increases vasopressin which decreases urine output

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16
Q

How likely is it that you don’t see DO on UDS in an OAB patient?

17
Q

Pros and cons of TLH with SCP

A

Possibly increased risk of mesh erosion
Higher risk of injury to ureters, bladder or bowel?

Pros:
No need for morcellation
No need for cervical cancer surveillance

18
Q

Name 2 hemostatic agents that do not contain human blood products.

A

Surgicel-Cellulose
Arista-Polysaccharide spheres

19
Q

What is the rate of kinking/injury to the ureter with a USLS procedure?

A

Vaginal 10%
Laparoscopic 0%

20
Q

How do you decide to leave a foley in place after urethral prolapse excision?

A

if the prolapse is large to avoid urethral stricture

21
Q

You suspect urethral diverticulum, but MRI is not available.

What other imaging study can you order?

A

retrograde urethrogram using a trattner catheter to occlude both ends of the urethra and fill the urethra with contrast

OR

VCUG

22
Q

What type of epithelium lines the urethra?

A

proximal 1/3 - transitional epithelium
distal 2/3 - squamous epithelium

23
Q

Name some histologic changes commonly found in urethral diverticulua

A

squamous metaplasia,
adenomatous metaplasia,
cystitis cystica
cystitis glandulari

24
Q

Malignancy types associated with urethral diverticulum

A

Adenocarcinoma > transitional cell > squamous cell

25
most common type of bladder cancer?
>90 % urothelial (transitional cell) carcinoma US and Europe Non-urothelial cancer internationally due to schistosomiasis.
26
hematuria work up and CT is contraindicated. What other imaging coud you do?
MR urogram or renal US
27
Microhematuria work up is negative. what are her next steps
SDM regarding whether or not to test again
28
Gemtesa drug interaction to be worried about.
digoxin. need to monitor levels before, during, and after use
29
how does botox work?
binds to the SNAP-25 protein which prevents the release of ACh at the motor neuro synapse.