Types Of Transport, Cell physiology miscellaneous Flashcards
Glucose transport in muscle and adipose
Facilitated diffusion
Na K ATPase
Primary active
Ca ATPase
Ca pump in the sarcoplasmic reticulum
Primary active transport
HKATPase
Primary active transport
Inhibitors of Na K ATPase pump (2)
Cardiac glycosides : ouabain, digitalis
Na glucose in the small intestine
Cotransport ( secondary active)
NaKCl in renal TAL
Cotransport (secondary active)
NaCa and NaH
Countertransport (secondary active)
Blocked by tetrodotoxin and lidocaine, thereby abolishing action potentials
Voltage-sensitive Na channels
Blocked by tetraethylammonium
Voltage gated K channels
Blocks release of Ach from presynaptic terminals
Total blockade of transmission
Botulinum toxin
Competes with Ach for receptors on motor endplate
Decreases size of EPP, maximal doses cause paralysis of respiratory muscles
Curare
Inhibits acetylcholinesterase
Prolongs and enhances action of Ach at muscle end plate
Tx of myasthenia gravis
Neostigmine
Blocks reuptake of choline into presynaptic terminal
Depletes Ach stores from presynaptic terminal
Hemicholinium
Sleep wave
Eyes open
Beta