Neurotransmitters Flashcards
Prominent in midbrain
Inhibits prolactin secretion
Metabolized by MAO and COMT
Dopamine
Present in high concn in brainstem
Formed from tryptophan
Coverted ro melatonin in pineal gland
Serotonin
Formed from histidine
Present in hypothalamic neurons
Histamine
Most prevalent excitatory NT in brain
Ionotropic receptor subtype includes NMDA
Metabotropic receptors tied to G protein
Glutamate
Inhibitory NT found primarily in SC and bstem
Increases Cl conductance
Glycine
Short-acting inhibitory NT in GI tract, BV, CNS
Synthesized in presynaptic terminals, where NO synthase converts arginine to citrulline and NO
Nitric oxide
Receptor site for BZD and barbiturates
Inc Cl conductance
GABAa
Receptor that increases K conductance
GABAb