GI Hormones Flashcards
Homology (family)
Gastrin
Gastrin-CCK
Homology (family)
CCK
Gastrin-CCK
Homology (family)
Secretin
Secretin-glucagon
Homology (family)
GIP
Secretin-glucagon
Site of secretion
Gastrin
G cells of stomach antrum
Parietal cellsi
Site of secretion
CCK
I cells of duodenum and jejunum
Site of secretion
Secretin
S cells of duodenum
Site of secretion
GIP
Duodenum and jejunum
Stimulus for secretion (3)
Gastrin
Small peptides and amino acids
Distention of stomach
Vagus (via Gastrin releasing peptide)
Inhibitor of gastrin
H+ in stomach
Somatostatin
Stimulus of secretion (2)
CCK
Small peptides and AA
Fatty acids
Stimulus of secretion
Secretin
H+ in duodenum
Fatty acids in duodenum
Stimulus of secretion
GIP
Fatty acids, AA
Oral glucose
Action
Gastrin
Increase gastric acid secretion
Growth of mucosa
Action
CCK
Contraction of gallbladder and relaxation of sphincter of oddi
Increased pancreatic enzyme and bicarbonate secretion
Growth of exocrine pancreas /gallbladder
Inhibits gastric emptying
Action
Secretin
Increased pancreatic bicarbonate secretion
Increased biliary biarbonate secretion
Decrease gastric H secretion
Action
GIP
Increase insulin secretion
Decrease gastric acid secretion
2 hormones that inhibit gastric acid secretion
Secretin
GIP
Hormone that inhibits gastric emptying
CCK
Hormones that increase pancreatic bicarbonate secretion
CCK
Secretin
Stimulates growth of exocrine pancreas
CCK
Insulin secretion
GIP
