GI Hormones Flashcards

1
Q

Homology (family)

Gastrin

A

Gastrin-CCK

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2
Q

Homology (family)

CCK

A

Gastrin-CCK

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3
Q

Homology (family)

Secretin

A

Secretin-glucagon

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4
Q

Homology (family)

GIP

A

Secretin-glucagon

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5
Q

Site of secretion

Gastrin

A

G cells of stomach antrum

Parietal cellsi

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6
Q

Site of secretion

CCK

A

I cells of duodenum and jejunum

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7
Q

Site of secretion

Secretin

A

S cells of duodenum

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8
Q

Site of secretion

GIP

A

Duodenum and jejunum

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9
Q

Stimulus for secretion (3)

Gastrin

A

Small peptides and amino acids
Distention of stomach
Vagus (via Gastrin releasing peptide)

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10
Q

Inhibitor of gastrin

A

H+ in stomach

Somatostatin

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11
Q

Stimulus of secretion (2)

CCK

A

Small peptides and AA

Fatty acids

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12
Q

Stimulus of secretion

Secretin

A

H+ in duodenum

Fatty acids in duodenum

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13
Q

Stimulus of secretion

GIP

A

Fatty acids, AA

Oral glucose

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14
Q

Action

Gastrin

A

Increase gastric acid secretion

Growth of mucosa

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15
Q

Action

CCK

A

Contraction of gallbladder and relaxation of sphincter of oddi
Increased pancreatic enzyme and bicarbonate secretion
Growth of exocrine pancreas /gallbladder

Inhibits gastric emptying

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16
Q

Action

Secretin

A

Increased pancreatic bicarbonate secretion
Increased biliary biarbonate secretion

Decrease gastric H secretion

17
Q

Action

GIP

A

Increase insulin secretion

Decrease gastric acid secretion

18
Q

2 hormones that inhibit gastric acid secretion

A

Secretin

GIP

19
Q

Hormone that inhibits gastric emptying

A

CCK

20
Q

Hormones that increase pancreatic bicarbonate secretion

A

CCK

Secretin

21
Q

Stimulates growth of exocrine pancreas

A

CCK

22
Q

Insulin secretion

A

GIP