Acid Base Disorders Flashcards

1
Q

Primary disturbance

Metabolic acidosis

A

Decreased HCO3

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2
Q

Primary disturbance

Metabolic alkalosis

A

Increased HCO3-

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3
Q

Primary disturbance

Repiratory acidosis

A

Increased CO2

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4
Q

Primary disturbance

Respiratory alkalosis

A

Decreased CO2

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5
Q

Respiratory compensation

Metabolic acidosis

A

Hyperventilation

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6
Q

Respiratory compensation

Metabolic alkalosis

A

Hypoventilation

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7
Q

Respiratory compensation

Respiratory alkalosis

A

None

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8
Q

Respiratory compensation

Respiratory acidosis

A

None

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9
Q

Renal compensation

Metabolic acidosis

A

None

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10
Q

Renal compensation

Metabolic alkalosis

A

None

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11
Q

Renal compensation

Respiratory acidosis

A

Increased H excretion

Increased HCO3 reabsorption

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12
Q

Renal compensation

Respiratory alkalosis

A

Decreased renal H excretion

Decreased HCO3 reabsorption

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13
Q

Chronic renal failure

A

Metabolic acidosis
Failure to excrete H as titrable acid and NH4
Increased anoin gap

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14
Q

Salicylate intoxication

A

Metabolic acidosis, by increasing anion gap

Repiratory alkalosis by direct stimulation of medullary respiratory center

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15
Q

Methanol/formaldehyde intoxication

A

Metabolic acidosis
Produces formic acid
Increased anion gap

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16
Q

Ethylene glycol intoxication

A

Metabolic acidosis
Produces glycolic and oxalic acid
Increased anion gap

17
Q

Diarrhea

A

Metabolic acidosis
GI loss of HCO3
Normal anion gap

18
Q

Type 1, 2, 4 RTA

A

Metabolic acidosis
1 failure to excrete titratable acid and NH4, normal AG
2 renal loss of bicarbonate
4 hypoaldosteronism, failure to excrete NH4, hyperkalemia caused by lack of aldosterone inhibits NH3 synthesis, normal anion gap

19
Q

Vomiting

A

Metabolic alkalosis

Loss of gastric H, hypo K, volume contraction, may have increase anion gap due to increased ketoacids in starvation

20
Q

Hyperaldosteronism

A

Metabolic alkalosis

Increased H secretion by distal tubule, increased new HCO3 reabsorption

21
Q

Loop or thiazide diuretics

A

Metabolic alkalosis (volume contraction alkalosis)

22
Q

Airway obstruction

A

Respiratory acidosis

23
Q

ARDS

COPD

A

Respiratory acidosis

24
Q

Opiates, sedatives, anesthetics

A

Respiratory acidosis

Inhibition of medullary respiratory center

25
Q

GBS, Polio, ALS, multiple sclerosis

A

Respiratory acidosis

Weakening of respiratory muscles

26
Q

Pneumonia

A

Respiratory alkalosis

Hypoxemia—>increase ventilatory rate

27
Q

Pulmonary embolus

A

Respiratory alkalosis

Hypoxemia—>ventilatory rate

28
Q

High altitude

A

Respiratory alkalosis

Hypoxemia increases ventilatory rate