Type 2 Diabetes Flashcards
Pathophysiology of T2DM
Repeated exposure to glucose + insulin —> B cells hyperplasia/hypertrophy —> resistance
Risk factors
- modifiable
- non-modifiable
Presentation
Similar to T1DM (excluding ketogenesis symptoms)
Timing of the day to perform OGTT
Prior to breakfast
HbA1c in pre diabetics
42-47 mmol/mol
Fasting glucose in pre-diabetics
6.1-6.9 mmol/l
OGTT in pre-diabetics
7.8-11 mmol/l
HbA1C in diabetics
> 48 mmol/mol
Random glucose in diabetics
> 11 mmol/l
Fasting glucose in diabetics
> 7 mmol/l
OGTT in diabetics
> 11 mmol/l
Dietary modifications to manage T1DM
- vegetables + oily fish
- low sugar, high fibre diet
How can T2DM be curable
- right lifestyle changes
- management of side effects
HbA1C target for a new T2DM diagnosis
48 mmol/mol
HbA1C in diabetics who moved beyond metformin
53 mmol/mol